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Structural Modification and Biological Activity of Polysaccharides

Molecules, 2023
Natural polysaccharides are macromolecular substances with a wide range of biological activities. The structural modification of polysaccharides by chemical means can enhance their biological activity.
Ting Zhao, Min Yang, Lina Ma, Xinglong Liu, Qiteng Ding, Guodong Chai, Yang Lu, Hewei Wei, Shuai Zhang, Chuanbo Ding   +9 more
doaj   +6 more sources

Chemical Modification of Polysaccharides: A Review of Synthetic Approaches, Biological Activity and the Structure–Activity Relationship

Molecules, 2023
Natural polysaccharides are macromolecular substances with great potential owing to their wide biological activity and low toxicity. However, not all polysaccharides have significant pharmacodynamic activity; hence, appropriate chemical modification ...
Tianbo Liu, Qianqian Ren, Shuang Wang, Jianing Gao, Congcong Shen, Shengyu Zhang, Yanhong Wang, Feng Guan   +7 more
doaj   +4 more sources

The biogenesis, biological functions and modification of Circular RNAs

Experimental and Molecular Pathology, 2023
Circular RNAs are covalently closed and non-coding in eukaryotes, which have tissue- specific and temporal-specific expression patterns whose biogenesis is regulated by transcription and splicing. Most circular RNAs are localized in the cytoplasm.
Sen, Liu, Xiang Yu, Guo, Qing Juan, Shang, Peng, Gao   +3 more
exaly   +3 more sources

Microbial Inhibition of Fusarium Pathogens and Biological Modification of Trichothecenes in Cereal Grains [PDF]

Toxins, 2017
Urszula Wachowska, Danuta Packa, Marian Wiwart   +2 more
exaly   +2 more sources

Distribution and regulatory roles of oxidized 5-methylcytosines in DNA and RNA of the basidiomycete fungi Laccaria bicolor and Coprinopsis cinerea

Open Biology, 2022
The formation of three oxidative DNA 5-methylcytosine (5mC) modifications (oxi-mCs)—5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC) and 5-carboxylcytosine (5caC)—by the TET/JBP family of dioxygenases prompted intensive studies of their functional ...
Janina Ličytė, Kotryna Kvederavičiūtė, Audronė Rukšėnaitė, Eglė Godliauskaitė, Povilas Gibas, Vita Tomkutė, Gražina Petraitytė, Viktoras Masevičius, Saulius Klimašauskas, Edita Kriukienė   +9 more
doaj   +1 more source

Multiomics Analysis of Neuroblastoma Cells Reveals a Diversity of Malignant Transformations

Frontiers in Cell and Developmental Biology, 2021
Neuroblastoma (NB) is a pediatric cancer of the developing sympathetic nervous system that exhibits significant variation in the stage of differentiation and cell composition of tumors.
Milda Narmontė, Povilas Gibas, Kristina Daniūnaitė, Kristina Daniūnaitė, Juozas Gordevičius, Edita Kriukienė   +5 more
doaj   +1 more source

Functionalised nanopores: chemical and biological modifications

Chemical Science, 2022
The convergence of chemistry, biology, and solid-state approaches enables the construction hybrid nanopores with enhanced single-molecule applications.
Dominic F. Cairns-Gibson, Scott L. Cockroft   +1 more
openaire   +4 more sources

Structural, Physicochemical, and Functional Properties of Wheat Bran Insoluble Dietary Fiber Modified With Probiotic Fermentation

Frontiers in Nutrition, 2022
Insoluble dietary fiber (IDF) were isolated from wheat bran (WB) after microbial fermentation with single or mixed strain [Lactobacillus plantarum, Lactobacillus acidophilus, Bacillus subtilis or mixed lactic acid bacteria (L.
Ai-Mei Liao, Jie Zhang, Zhen-Lin Yang, Ji-Hong Huang, Ji-Hong Huang, Ji-Hong Huang, Long Pan, Yin-Chen Hou, Yin-Chen Hou, Xiao-Xiao Li, Peng-Hui Zhao, Yu-Qi Dong, Zhe-Yuan Hu, Ming Hui, Ming Hui   +14 more
doaj   +1 more source

Perspectives on lecithin from egg yolk: Extraction, physicochemical properties, modification, and applications

Frontiers in Nutrition, 2023
Egg yolk lecithin has physiological activities as an antioxidant, antibacterial, anti-inflammatory, and neurologic, cardiovascular, and cerebrovascular protectant.
Feng Zhao, Rongji Li, Yun Liu, Haiyan Chen, Haiyan Chen   +4 more
doaj   +1 more source

Sono‐Activatable Semiconducting Polymer Nanoreshapers Multiply Remodel Tumor Microenvironment for Potent Immunotherapy of Orthotopic Pancreatic Cancer

Advanced Science, 2023
Due to the complicated tumor microenvironment that compromises the efficacies of various therapies, the effective treatment of pancreatic cancer remains a big challenge.
Meng Li, Yue Liu, Yijing Zhang, Ningyue Yu, Jingchao Li   +4 more
doaj   +1 more source