Irreducible coupling between physical and biological phenomena: overview of on-line and off-line physical measurements during high cell density cultures of yarrowia lipolytica [PDF]
During cell cultures in bioreactor, micro-organism physiology closely interacts with physico-chemical parameters (gas and feed flow rates, mixing, temperature, pH, pressure).
Anne-Archard, Dominique +3 more
core
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Biological Modification of Arrhythmogenic Substrates by Cell-Free Therapeutics. [PDF]
Lin YN +2 more
europepmc +1 more source
Biotechnological modification and functionalisation of polyester surfaces [PDF]
Synthetic fibers form an important part of the textile industry, the production of polyester alone surpassing that of cotton. A disadvantage of synthetic fibers is their low hydrophilicity. Polyester fibers are particularly hydrophobic.
Kiekens, Paul +2 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The treatment of internal hemorrhage remains challenging due to the current limited antibacterial capability, hemostatic efficacy, and biocompatibility of hemostatic materials.
Lu Liu +5 more
doaj +1 more source
Biological modification of pentosans in wheat B starch wastewater and preparation of a composite film. [PDF]
Li P, Zhao F, Wei X, Tao X, Ding F.
europepmc +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Dendrimer‐Based Nanodrugs for Chemodynamic Therapy of Tumors
To realize precise tumor treatment, chemodynamic therapy (CDT) that utilizes metal element to trigger Fenton or Fenton‐like reaction to generate cytotoxic hydroxyl radicals in tumor region has been widely investigated.
Caiyun Zhang +3 more
doaj +1 more source

