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Chitosan: Structural modification, biological activity and application
International Journal of Biological Macromolecules, 2020Many by-products that are harmful to the environment and human health are generated during food processing. However, these wastes are often potential resources with high-added value. For example, crustacean waste contains large amounts of chitin. Chitin is one of the most abundant polysaccharides in natural macromolecules, and is a typical component of
Changhu Xue, Xiangzhao Mao
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Biological Effects of Modifications of the Englerin A Glycolate
ACS Medicinal Chemistry Letters, 2022Modifications at the glycolate moiety of englerin A were made to explore variations at the most sensitive site on the molecule for activity in the NCI 60 screen, wherein englerin A is highly potent and selective for renal cancer cells. Replacement of the glycolate by other functionalities as well as esterification of the glycolate hydroxyl yielded ...
Sarath P. D. Seenadera +10 more
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Traditional Chinese Medicine (TCM) has been used to treat diseases in China for thousands of years. TCM compositions are complex, using as their various sources plants, animals, fungi, and minerals.
Yun Chen, Fangke Yao, Ke Ming
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Modification and biological role of histone
Hereditas (Beijing), 2012Histone is one of critical components of chromatin, which amino acid residues at the N-terminus can be covalently modified. Histone modification (HM) can change the chromatin conformation and induce transcription or gene silencing. Not only can HM control gene expression, but also participate in cell division, cell apoptosis and memory formation by ...
Wei WANG, Zhi-Qi MENG, Fang-Xiong SHI
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Physical and biological modification of carbonic sorbents
Clinical Materials, 1992Activated carbons are usually considered as non-specific sorbents. However, their specificity and effectiveness may be increased by physical and biological modifications. This paper gives our approach and discusses the results of some related recent studies.
V. G. Nikolaev +4 more
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MODIFICATION OF BIOLOGIC RESPONSE IN EXPERIMENTAL HYPERSENSITIVITY
Journal of the American Medical Association, 1949Recently there has been wider acceptance of the view that a particular group of diseases and certain reactions to therapeutic agents occur on the basis of an acquired hypersensitivity. There is evidence that rheumatic fever, glomerulonephritis, serum sickness and periarteritis nodosa belong in this category,1and some have added to this group acute ...
G J, DAMMIN, S C, BUKANTZ
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Protein modification and its biological role
International Journal of Biochemistry, 1985The modifications present on a polypeptide play an important role in determining its eventual fate. Modifications, particularly proteolysis, are important in the generation of biological activity. Modifications are used to "target" particular polypeptides to specific cellular locations.
B R, Moore, S J, Free
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Chemical Modifications and Biological Activities of Polysaccharides
Current Drug Targets, 2016The chemical modifications of polysaccharides involve the use of chemical methods to modify some special structures or functional groups of polysaccharides on the main chains or side chains. The chemical methods include sulfation, phosphorylation, acetylation, carboxymethylation etc.
Gangliang, Huang +2 more
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Chemical Modifications of Pyridoxine for Biological Applications: An Overview
Current Topics in Medicinal Chemistry, 2023Abstract: Pyridoxine and its derivatives, pyridoxamine, and pyridoxal have been recognized for more than 70 years and are known for regulating cellular biology and metabolism. During the past few decades, the anti-oxidant and anti-inflammatory properties of pyridoxine and its vitamers were explored.
Rajashree, Pawar +3 more
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Biological modification of oil composition
Journal of the American Oil Chemists' Society, 1985AbstractProspects for modification of palm oil composition through oil palm breeding, tissue culture and enzyme‐catalyzed transesterification are reviewed. Present emphasis in oil modification is toward greater unsaturation. The greatest prospect for this area lies in the interspecific hybridization ofE. oleifera andE. guineensis.
B. K. Tan +3 more
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