Results 171 to 180 of about 30,881 (256)

Neurofilament light chain as in vitro and clinical biomarker of vincristine‐induced peripheral neuropathy

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Vincristine‐induced peripheral neuropathy (VIPN) is a common side effect in children and adolescents treated with vincristine. Assessing VIPN, especially in young children, is challenging due to a lack of sensitive tools. This limits our understanding of the nature and risk factors of VIPN. This study aimed to investigate neurofilament light chain
Peter Erik Lotko Pontoppidan   +8 more
wiley   +1 more source

A phase 1 study to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of PF‐07261271 in healthy participants

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim There is an unmet need for more effective therapies in inflammatory bowel disease (IBD). A single drug that blocks multiple distinct pathogenic pathways may offer therapeutic benefit superior to current monotherapies. PF‐07261271, a bispecific antibody targeting both the p40 subunit of interleukin‐12/23 and tumour necrosis factor‐like cytokine 1A ...
Srividya Neelakantan   +11 more
wiley   +1 more source

Redox chemistry of early Earth and the origin of life. [PDF]

open access: yesCommun Chem
Moldogazieva NT   +3 more
europepmc   +1 more source

The hidden potential of archaea in carbon and nitrogen cycling in agricultural soils: a review. [PDF]

open access: yesFront Microbiol
Speek BM   +5 more
europepmc   +1 more source

Counting cases, conserving species: addressing highly pathogenic avian influenza in wildlife

open access: yesBiological Reviews, EarlyView.
ABSTRACT Highly pathogenic avian influenza (HPAI) has become a critical threat to wildlife, shifting from a seasonal epizootic to a persistent, year‐round panzootic with global consequences. Here, we summarise the origin, evolutionary mechanisms, and expanding host range of the current H5N1 virus (clade 2.3.4.4b) and assess its impact on wildlife. Over
Ulrich Knief   +4 more
wiley   +1 more source

Porous Carbon Materials for Carbon Dioxide Capture

open access: yesCarbon Energy, EarlyView.
This work aims to address the current status and challenges associated with the regulation of pore structures, as well as the influence of pore structures on CO2 capture. Systematic quantitative analysis of structure–property relationships, combined with machine learning approaches, can effectively evaluate the contributions of structural ...
Zhifu Liu   +6 more
wiley   +1 more source

Redefining the Nitrogen Cycle Through Electronic Configuration Driven Electrocatalysis for Low Carbon Energy

open access: yesCarbon Energy, EarlyView.
This review reveals how electronic configuration engineering governs the entire electrocatalytic nitrogen cycle, providing structure‐informed insights into reaction selectivity, catalytic durability, and sustainable nitrogen utilization across energy and environmental systems. ABSTRACT The global nitrogen cycle is essential to food production, chemical
Jiamu Feng   +7 more
wiley   +1 more source

Light and dark conditions control the nitrous oxide uptake and emission dynamics in a subarctic, nutrient-poor permafrost peatland. [PDF]

open access: yesCommun Earth Environ
Triches NY   +13 more
europepmc   +1 more source

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