Results 31 to 40 of about 2,999,960 (264)

Lipid oxidation in foods and its implications on proteins

open access: yesFrontiers in Nutrition, 2023
Lipids in foods are sensitive to various environmental conditions. Under light or high temperatures, free radicals could be formed due to lipid oxidation, leading to the formation of unstable food system.
Lianxin Geng   +3 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Optimization of Extraction Process of Polysaccharides from Hovenia dulcis Fruit Pedicels and Its Antioxidant Activity

open access: yesShipin gongye ke-ji, 2023
The aim of this study was to obtain polysaccharides from Hovenia dulcis fruit pedicels, and further evaluate its ability to scavenge free radicals and inhibit the oxidation of biological macromolecules (proteins, lipids, DNA).
Xudong LIU   +6 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Development of Pillared Clays for Wet Hydrogen Peroxide Oxidation of Phenol and Its Application in the Posttreatment of Coffee Wastewater

open access: yesInternational Journal of Photoenergy, 2012
This paper focuses on the use of pillared clays as catalysts for the Fenton-like advanced oxidation, specifically wet hydrogen peroxide catalytic oxidation (WHPCO).
Nancy R. Sanabria   +2 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Supplementation of Japanese Quail (Coturnix coturnix japonica) Breeders with Tagetes erecta Flower Extract and Vitamin E Improves the Oxidative Status of Embryos and Chicks

open access: yesPoultry, 2023
The effects of Tagetes erecta flower extract (TFE) and increasing levels of vitamin E (VE) in the diet of Japanese quail breeders on progeny performance and oxidative status were studied.
Lenilson Fonseca Roza   +8 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Advanced catalytic oxidation coupled to biological systems to treat pesticide-contaminated water: A review on technological trends and future challenges

open access: yesWater Science and Technology, 2022
This article had the one and only objective of consolidating the couplings of advanced oxidation processes and biological systems in the decontamination of wastewater with pesticide content reported in the Scopus and Web of Science databases, through a ...
Joseph Soto-Verjel   +2 more
doaj   +1 more source

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