Results 1 to 10 of about 635,426 (265)
Mapping parameter spaces of biological switches.
PLoS Computational Biology, 2021 Since the seminal 1961 paper of Monod and Jacob, mathematical models of biomolecular circuits have guided our understanding of cell regulation. Model-based exploration of the functional capabilities of any given circuit requires systematic mapping of ...
Rocky Diegmiller +7 more
doaj +4 more sources
UNified FramewOrk for reguLatory Dynamics (UNFOLD): Dissecting robustness, plasticity, evolvability and canalisation of biological function. [PDF]
PLoS Computational BiologyA unique balance of seemingly contradictory properties like robustness and plasticity, or evolvability and functional canalisation, characterises biological systems. To understand the basis of these properties, we investigate gene regulation, which is at
Debomita Chakraborty +2 more
doaj +2 more sources
Children, 2021 Background: Many pediatric studies describe the association between biological parameters (BP) and severity of sickle cell disease (SCD) using different methods to collect or to analyze BP.
Julie Sommet +7 more
doaj +1 more source
Известия ТИНРО, 2023 Data on juvenile pink salmon from the continental coast of the Okhotsk Sea obtained in 1960s–2010s are summarized. The timing and dynamics of their downstream migration are considered in terms of biological parameters and nutrition.
S. L. Marchenko
doaj +1 more source
Turkish Journal of Agriculture: Food Science and Technology, 2023 The Brown marmorated stink bug (BMSB) [Halyomorpha halys (Hemiptera: Pentatomidae)] is a polyphagous pest causing significant damage to approximately 300 crops, such as nuts, vegetables, and ornamentals.
İsmail Oğuz Özdemir +2 more
doaj +1 more source
State of stocks of pacific salmons in the basin of Avacha Bay (southeastern Kamchatka) in 1985–2019
Известия ТИНРО, 2020 State of pacific salmon stocks is considered for the basins of the Avacha and Paratunka Rivers in 1985–2019. Significant decline of the stocks is noted that is associated with anthropogenic impact growth. Total number of producers for five salmon species
G. V. Zaporozhets, O. M. Zaporozhets
doaj +1 more source
Известия ТИНРО, 2021 Morphological signs (32 plastic and 7 meristic) and biological parameters (size, weight, age and sexual structure, fecundity) are considered for weather loaches of gen.
E. V. Ostrovskaya, A. P. Kasatkina
doaj +1 more source
Approaches to Parameter Estimation from Model Neurons and Biological Neurons
Algorithms, 2022 Model optimization in neuroscience has focused on inferring intracellular parameters from time series observations of the membrane voltage and calcium concentrations.
Alain Nogaret
doaj +1 more source
Automating parameter selection to avoid implausible biological pathway models
npj Systems Biology and Applications, 2021 A common way to integrate and analyze large amounts of biological “omic” data is through pathway reconstruction: using condition-specific omic data to create a subnetwork of a generic background network that represents some process or cellular state.
Chris S. Magnano, Anthony Gitter
doaj +1 more source
Utility of constraints reflecting system stability on analyses for biological models.
PLoS Computational Biology, 2022 Simulating complex biological models consisting of multiple ordinary differential equations can aid in the prediction of the pharmacological/biological responses; however, they are often hampered by the availability of reliable kinetic parameters. In the
Yoshiaki Kariya +4 more
doaj +1 more source