Results 31 to 40 of about 196,073 (265)
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Biological evolution and statistical physics [PDF]
This review is an introduction to theoretical models and mathematical calculations for biological evolution, aimed at physicists. The methods in the field are naturally very similar to those used in statistical physics, although the majority of publications appeared in biology journals. The review has three parts, which can be read independently.
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Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
PHYSICAL AND BIOLOGICAL OBSERVATIONS ON HERPESVIRUS [PDF]
Smith, KendallO. (Baylor University College of Medicine, Houston, Texas). Physical and biological observations on herpesvirus. J. Bacteriol.86:999–1009. 1963.—The development of herpesvirus in human lung fibroblasts was studied by plaque assays and physical particle counts. Approximately 200 infectious units and 60,000 particles were produced by single
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The Biological Frontier of Physics [PDF]
Problems at the interface between biology and physics offer unique opportunities for physicists to make quantitative contributions to biology. Equally important, they enrich the discipline of physics by challenging its practitioners to think in new ways.
Rob Phillips, Stephen R. Quake
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Biophysical approaches for studying viral entry
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
Biological Evolution and Statistical Physics [PDF]
Molecular information and evolution.- Statistical significance and extremal ensemble of gapped local hybrid alignment.- On the design of optimization criteria for multiple sequence alignment.- Red queen dynamics and the evolution of translational redundancy and degeneracy.- A testable genotype-phenotype map: modeling evolution of RNA molecules ...
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Cours of physics in the modular learning programs for students
This paper describes one of the implementation methods of modular learning on the Faculty of Medicine. The general approach to the design of modular learning programs is provided. The «Metabolism» modular unit exemplifies teaching methodology.
Y S Arhangelskaya, L A Kosir
doaj
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source

