Results 11 to 20 of about 1,240,733 (309)

Emergence of a novel recombinant of CV-A5 in HFMD epidemics in Xiangyang, China

BMC Medical Genomics, 2021
Background Hand, foot and mouth disease (HFMD) is caused by a variety of enterovirus serotypes and the etiological spectrum worldwide has changed since a large scale of outbreaks occurred in 1997.
Yuting Yu, Zhiyu Luo, Weiping Jin, Jianyi Mai, Shasha Qian, Jia Lu, Zhenni Wei, Shengli Meng, Zejun Wang, Xuhua Guan, Yeqing Tong, Shuo Shen   +11 more
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Alum/CpG Adjuvanted Inactivated COVID-19 Vaccine with Protective Efficacy against SARS-CoV-2 and Variants

Vaccines, 2022
Since the beginning of the COVID-19 pandemic, numerous variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have emerged, including five variants of concern (VOC) strains listed by the WHO: Alpha, Beta, Gamma, Delta and Omicron ...
Yuntao Zhang, Xiaotong Zheng, Wang Sheng, Hongyang Liang, Yuxiu Zhao, Xiujuan Zhu, Rong Yang, Yadan Zhang, Xiaofei Dong, Weidong Li, Fei Pei, Ling Ding, Zhen Chang, Li Deng, Guangying Yuan, Zhaona Yang, Di Zhu, Xiaoming Yang, Hui Wang   +18 more
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Selection of sterilizing-grade filter for preparation of human coagulation factor Ⅷ/ von Willebrand factor complex

Zhongguo shuxue zazhi, 2023
Objective To screen the sterilizing-grade filters applicable for production of human coagulation factor Ⅷ/von Willebrand factor complex(FⅧ/VWF)and study the sterilization filtration process.
Quanjuan GUO, An ZHOU, Wenjie LIU, Yike XU, Wenqiang SHI, Chen CHEN, Changyong JIAN   +6 more
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Study on the change of neutralizing antibody level in plasma donors after a third shot of inactivated novel coronavirus vaccine

Zhongguo shuxue zazhi, 2023
Objective To investigate the trend of neutralizing antibody level in plasma donors who received the 3rd shot of inactivated novel coronavirus vaccine.
Wenjuan GE, An ZHOU, Junying SHEN, Xiaoqing LI, Jie MA, Mengzhao ZHU, Changyong JIAN   +6 more
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Virological Characteristics of Five SARS-CoV-2 Variants, Including Beta, Delta and Omicron BA.1, BA.2, BA.5

Viruses, 2023
SARS-CoV-2 variants of concern (VOCs) show increasing transmissibility and infectivity and induce substantial injuries to human health and the ecology. Therefore, it is vital to understand the related features for controlling infection.
Yan Zeng, Fei Xia, Changfu Guo, Chunxia Hu, Yuwei Li, Xiang Wang, Qin Wu, Zhuo Chen, Jia Lu, Zejun Wang   +9 more
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Development and Preliminary Application of a Droplet Digital PCR Assay for Quantifying the Oncolytic Herpes Simplex Virus Type 1 in the Clinical-Grade Production

Viruses, 2023
Oncolytic herpes simplex virus (oHSV) is a type of virus that selectively targets and kills cancer cells, leaving normal cells unharmed. Accurate viral titer is of great importance for the production and application of oHSV products. Droplet digital PCR (
Miaomiao Guo, Li Deng, Hongyang Liang, Yuyao Du, Wenrui Gao, Na Tian, Ying Bi, Jinghua Li, Tiancong Ma, Yuntao Zhang, Hui Wang   +10 more
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Identification of a Conserved, Linear Epitope on VP3 of Enterovirus A Species Recognized by a Broad-Spectrum Monoclonal Antibody

Viruses, 2023
Outbreaks of hand, foot and mouth disease (HFMD) have occurred frequently in the Asian-Pacific region over the last two decades, caused mainly by the serotypes in Enterovirus A species.
Lie Fu, Xiao-Yu Zhang, Wei-Ping Jin, Chen Wang, Sha-Sha Qian, Meng-Jun Wang, Wen-Hui Wang, Sheng-Li Meng, Jing Guo, Ze-Jun Wang, Xiao-Qi Chen, Shuo Shen   +11 more
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Comparative Study on MNVT of OPV Type I and III Reference Products in Different Periods

Diseases, 2023
Widespread vaccination using the oral live attenuated polio vaccine (OPV) and Sabin strain inactivated vaccine (sIPV) have greatly reduced the incidence of polio worldwide.
Xiyan Wang, Ruirui Ren, Bo Ma, Jing Xie, Yan Ma, Hong Luo, Yu Guo, Ling Ding, Liang Zhang, Mengyuan Zhang, Tianlang Wang, Zhichao Shuang, Xiujuan Zhu   +12 more
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Validation of the detection method for residual human coagulation factor Ⅺ in human prothrombin complex

Zhongguo shuxue zazhi, 2023
Objective To establish an enzyme-linked immunosorbent assay (ELISA) method for the determination of residual human coagulation factor Ⅺ in human prothrombin complex and validate the method.
Yong LIU, Yurong YU, Long YANG, Zexiu LI, Yao ZHANG, Jing DENG, Dan LI, Yunhua CHEN, Xuemei ZHAO   +8 more
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Safety and immunogenicity of a quadrivalent influenza vaccine in adults aged 60 years or above: a phase III randomized controlled clinical study

Human Vaccines & Immunotherapeutics, 2022
To control seasonal influenza epidemics in elders, a quadrivalent, inactivated, split-virion influenza vaccine (IIV4) comprising A and B lineages is produced for young individuals and adults aged ≥60 years.
Renfeng Fan, Xiaoyuan Huang, Xuanxuan Nian, Zhiqiang Ou, Jian Zhou, Jiayou Zhang, Peiyu Zeng, Wei Zhao, Jinglong Deng, Wei Chen, Shaomin Chen, Kai Duan, Yingshi Chen, Xinguo Li, Jikai Zhang, Xiaoming Yang   +15 more
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