Results 11 to 20 of about 2,638,691 (365)

Enhancing Inactivated Yellow Fever 17D Vaccine-Induced Immune Responses in Balb/C Mice Using Alum/CpG

open access: yesVaccines, 2023
There are some concerns about the safety of live attenuated yellow fever vaccines (YF–live), particularly viscerotropic adverse events, which have a high mortality rate.
Yadan Zhang   +15 more
doaj   +1 more source

Physiological search for quantum biological effects based on the Wigner-Yanase connection between coherence and uncertainty [PDF]

open access: yesAdvanced Quantum Technologies, 2300292 (2023), 2023
A fundamental concept of quantum physics, the Wigner Yanase information, is here used as a measure of quantum coherence in spin-dependent radical-pair reactions pertaining to biological magnetic sensing. This measure is connected to the uncertainty of the reaction yields, and further, to the statistics of a cellular receptor-ligand system used to ...
arxiv   +1 more source

Comparative multiomics analysis of cell physiological state after culture in a basket bioreactor

open access: yesScientific Reports, 2022
Bioreactors are one of the most important, basic pieces of equipment in the biopharmaceutical industry. Understanding the effects of mechanical damage and other factors on the physiological state of cells during cell matrix culture is the basis for ...
Shouzhi Yu   +6 more
doaj   +1 more source

Thermodynamic uncertainty relation to assess biological processes [PDF]

open access: yesJ. Chem. Phys. 154, 130901 (2021), 2021
We review the trade-offs between speed, fluctuations, and thermodynamic cost involved with biological processes in nonequilibrium states, and discuss how optimal these processes are in light of the universal bound set by the thermodynamic uncertainty relation (TUR).
arxiv   +1 more source

Development and Preliminary Application of a Droplet Digital PCR Assay for Quantifying the Oncolytic Herpes Simplex Virus Type 1 in the Clinical-Grade Production

open access: yesViruses, 2023
Oncolytic herpes simplex virus (oHSV) is a type of virus that selectively targets and kills cancer cells, leaving normal cells unharmed. Accurate viral titer is of great importance for the production and application of oHSV products. Droplet digital PCR (
Miaomiao Guo   +10 more
doaj   +1 more source

Emergence of a novel recombinant of CV-A5 in HFMD epidemics in Xiangyang, China

open access: yesBMC Medical Genomics, 2021
Background Hand, foot and mouth disease (HFMD) is caused by a variety of enterovirus serotypes and the etiological spectrum worldwide has changed since a large scale of outbreaks occurred in 1997.
Yuting Yu   +11 more
doaj   +1 more source

Comparative Study on MNVT of OPV Type I and III Reference Products in Different Periods

open access: yesDiseases, 2023
Widespread vaccination using the oral live attenuated polio vaccine (OPV) and Sabin strain inactivated vaccine (sIPV) have greatly reduced the incidence of polio worldwide.
Xiyan Wang   +12 more
doaj   +1 more source

Biological medicinal products: reference and biosimilar products – selected issues [PDF]

open access: yes, 2021
Biological therapies are being used in many chronic conditions. Development of biosimilar medicines gives chances for wider access to biological treatment.
Kobuszewski, Bartosz
core   +2 more sources

Selection of sterilizing-grade filter for preparation of human coagulation factor Ⅷ/ von Willebrand factor complex

open access: yesZhongguo shuxue zazhi, 2023
Objective To screen the sterilizing-grade filters applicable for production of human coagulation factor Ⅷ/von Willebrand factor complex(FⅧ/VWF)and study the sterilization filtration process.
Quanjuan GUO   +6 more
doaj   +1 more source

Alum/CpG Adjuvanted Inactivated COVID-19 Vaccine with Protective Efficacy against SARS-CoV-2 and Variants

open access: yesVaccines, 2022
Since the beginning of the COVID-19 pandemic, numerous variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have emerged, including five variants of concern (VOC) strains listed by the WHO: Alpha, Beta, Gamma, Delta and Omicron ...
Yuntao Zhang   +18 more
doaj   +1 more source

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