Results 21 to 30 of about 1,240,733 (309)

Repeat-Dose Toxicity of Candidate Omicron COVID-19 Vaccine in Sprague-Dawley Rats

open access: yesCOVID, 2022
Due to a large number of mutations in the spike protein and immune escape, the Omicron variant (B.1.1.529) has become a predominant variant of concern (VOC) strain.
Yuxiu Zhao   +18 more
doaj   +1 more source

Study on thedistribution of high titer neutralizing antibody against human cytomegalovirus in plasma donors

open access: yesZhongguo shuxue zazhi, 2022
Objective To investigate the distribution of plasma donors with high titer neutralizing antibodies against human cytomegalovirus (HCMV) in the general plasma donor population. Methods 920 plasma samples of Taibang were tested in April 2014 to investigate
Junying SHEN   +5 more
doaj   +1 more source

Comparison of Physical and Biochemical Characterizations of SARS-CoV-2 Inactivated by Different Treatments

open access: yesViruses, 2022
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused huge social and economic distress. Given its rapid spread and the lack of specific treatment options, SARS-CoV-2 needs to be inactivated according to strict biosafety measures during
Shouzhi Yu   +12 more
doaj   +1 more source

Advances in Next-Generation Coronavirus Vaccines in Response to Future Virus Evolution

open access: yesVaccines, 2022
Coronavirus disease (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread to more than 230 countries and territories worldwide since its outbreak in late 2019. In less than three years, infection by SARS-CoV-2 has
Lili Li   +8 more
doaj   +1 more source

Correction: Yu et al. Comparison of Physical and Biochemical Characterizations of SARS-CoV-2 Inactivated by Different Treatments. Viruses 2022, 14, 1938

open access: yesViruses, 2023
In the original publication [...]
Shouzhi Yu   +12 more
doaj   +1 more source

Biological Activities of Natural Products [PDF]

open access: yesMolecules, 2020
Natural products and their biological activities are currently a subject of great interest in the pharmaceutical, health food, and cosmetics industries, and numbers of scientific studies in this field are increasing rapidly [...]
Halina Maria Ekiert, Agnieszka Szopa
openaire   +3 more sources

Integrated Multi-Omic Characterization of the Detachment Process of Adherent Vero Cells with Animal-Based and Animal-Origin-Free Enzymes

open access: yesCells, 2022
Cell detachment techniques using animal-derived enzymes are necessary for the production of biopharmaceuticals that are made with the help of adherent cell cultures, although the majority of protein therapeutics (>USD 100 billion of income per year) are ...
Shouzhi Yu   +10 more
doaj   +1 more source

Reporter Coxsackievirus A5 Expressing iLOV Fluorescent Protein or Luciferase Used for Rapid Neutralizing Assay in Cells and Living Imaging in Mice

open access: yesViruses, 2023
Coxsackievirus A5 (CV-A5) is a re-emerging enterovirus that causes hand, foot, and mouth disease in children under five years of age. CV-A5-M14-611 is a mouse-adapted strain that can infect orally and lead to the death of 14-day-old mice.
Wei-Ping Jin   +7 more
doaj   +1 more source

An mRNA-based broad-spectrum vaccine candidate confers cross-protection against heterosubtypic influenza A viruses

open access: yesEmerging Microbes and Infections, 2023
Influenza virus is a prominent cause of respiratory illness in humans. Current influenza vaccines offer strain-specific immunity, while provide limited protection against drifted strains.
Feifei Xiong   +7 more
doaj   +1 more source

Research Advances on the Stability of mRNA Vaccines

open access: yesViruses, 2023
Compared to other vaccines, the inherent properties of messenger RNA (mRNA) vaccines and their interaction with lipid nanoparticles make them considerably unstable throughout their life cycles, impacting their effectiveness and global accessibility.
Feiran Cheng   +7 more
doaj   +1 more source

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