Results 121 to 130 of about 3,239,321 (318)
Book Review: Biological Psychiatry: Principles of Neuropsychopharmacology [PDF]
Meir Steiner
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Over the past three decades, non-invasive brain stimulation (NIBS) techniques have gained worldwide attention and demonstrated therapeutic potential in various medical fields, particularly psychiatry. The emergence of these novel techniques has led to an
Marine Mondino+52 more
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By integrating synaptic vesicle glycoprotein 2A PET imaging and transcriptomics, this study identifies Rho‐associated protein kinase 2 (ROCK2) as a critical regulator of synaptic network dysfunction in temporal lobe epilepsy. Pharmacological ROCK2 inhibition restores synaptic density and enhances mitophagy, thereby reducing seizures and neuronal damage.
Ling Xiao+14 more
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A brief summary of the articles appearing in this issue of Biological Psychiatry [PDF]
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Back to Basics: The Importance of Measurement Properties in Biological Psychiatry. [PDF]
Moriarity DP, Alloy LB.
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Strategies for Gene and Protein Expression Studies in Neuropsychopharmacology and Biological Psychiatry [PDF]
Husseini K. Manji
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This study identifies a functional noncoding variant, rs112651172 (C/G), that drives allele‐specific expression of PAXIP1‐AS1 in monozygotic twin pairs discordant for schizophrenia and bipolar disorder. The risk G allele enhances CEBPB binding, leading to lncRNA upregulation, CNTNAP3 derepression, and synaptic and behavioral deficits in mice.
Chaoying Ni+14 more
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Small animal imaging presents an opportunity for improving translational research in biological psychiatry. [PDF]
Chakravarty MM, Guma E.
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Proceedings of the 23rd Annual Meeting of the Japanese Society of Biological Psychiatry, 11‐13 April 2001, Nagasaki, Japan [PDF]
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A cost‐effective strategy is developed analyzing sub‐threshold GWAS loci (5 × 10−8 < P ≤ 10−6), identifying 180 risk loci and 304 high‐confidence genes through combined GWAS/subGWAS analysis. This approach reveals dendrite development and morphogenesis (DDM) as a novel SCZ pathway.
Rui Chen+15 more
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