Results 121 to 130 of about 467,262 (288)

Handbook of Biological Psychiatry: Part III Brain Mechanisms and Abnormal Behaviour-Genetics and Neuroendocrinology [PDF]

, 1981
J. F. Gibbons
openalex   +1 more source

NADH‐Reductive Stress Induced by Dihydrolipoamide Dehydrogenase Activation Contributes to Cuproptosis

Advanced Science, EarlyView.
This study demonstrates a cuproptosis mechanism involving nicotinamide adenine dinucleotide (NADH)‐reductive stress in neural cells. Copper activates dihydrolipoamide dehydrogenase under mitochondrial pH, accumulating NADH. Copper also induces mitochondrial permeability transition pore opening, facilitating NADH translocation to the cytosol and ...
Si‐Yi Zhang, Xing‐Hua Ren, Cheng‐Hong Zhang, Zhan‐You Wang   +3 more
wiley   +1 more source

Migrasomes in Ischemic Stroke: Molecular Landscape and Pathophysiological Impact

Advanced Science, EarlyView.
Multi‐omics profiling of stroke patients exposes systemic molecular fingerprints of immune activation, oxidative stress and metabolic collapse. Complement and coagulation cascade, and cholesterol metabolism emerge as shared functional hallmarks of plasma migrasomes in stroke patients and migrasomes isolated from experimental stroke mice.
Huifen Zhou, Yingying Zhang, Peng Zhou, Haofang Wan, Lingling Li, Bin Xu, Yuping Wan, Yingming Song, Yi Kang, Hongbo Zhang, Min Shi, Qun Hou, Jiehong Yang, Chen Ding, Wei Fu, Buchang Zhao, Haitong Wan   +16 more
wiley   +1 more source

The Aversive Brain System of Teleosts: Implications for Neuroscience and Biological Psychiatry

, 2018
Rhayra Xavier do Carmo Silva, Mônica Gomes Lima, Caio Maximino   +2 more
openalex   +2 more sources

Laparoscopic and Endoscopic Cooperative Surgery for Gastric Cancer as an Alternative Treatment in Elderly Patients: A Prospective Observational Study

Annals of Gastroenterological Surgery, EarlyView.
In a prospective study of 20 elderly gastric cancer patients who declined gastrectomy, laparoscopic and endoscopic cooperative surgery (LECS) was technically safe and preserved postoperative function. However, as oncological curability cannot be assured in advanced cases, careful selection and informed consent are essential.
Marie Washio, Keishi Yamashita, Takuya Wada, Mikiko Sakuraya, Hiroki Harada, Tadashi Higuchi, Koshi Kumagai, Yasushi Orihashi, Chika Kusano, Naoki Hiki   +9 more
wiley   +1 more source

Messaging in Biological Psychiatry: Misrepresentations, Their Causes, and Potential Consequences. [PDF]

Harv Rev Psychiatry, 2020
Dumas-Mallet E, Gonon F.
europepmc   +1 more source

Delivering a family‐based child mental health promotion program among two resettled refugee communities during the COVID‐19 pandemic: Lessons learned in a hybrid type II implementation‐effectiveness randomized controlled trial

American Journal of Community Psychology, EarlyView.
Abstract Background Resettled refugee families face elevated mental health risks, compounded by structural and cultural barriers. The Family Strengthening Intervention for Resettlement (FSIR), co‐developed with resettled refugee communities, aims to improve family functioning and child mental health.
Euijin Jung, Candace Black, Matias Placencio‐Castro, Lila Chamlagai, Rilwan Osman, Morgan Hoffman, William Beardslee, Theresa S. Betancourt   +7 more
wiley   +1 more source

A community‐driven approach to address substance use and create a Great Plains American Indian addiction and recovery research agenda

American Journal of Community Psychology, EarlyView.
Abstract Substance use, specifically opioid and methamphetamine use, is of increasing concern among American Indian (AI) populations in the Great Plains. This community‐driven participatory study investigated the impacts of substance use and community‐defined needs in treating addiction.
Brynn Luger, Anna Kihlström, Brinda Sivaramakrishnan, Allison Kelliher, Frankie Kropp, Carmen Rosa, T. John Winhusen, Donald Warne, the CTN0129 participating Tribal communities   +8 more
wiley   +1 more source

Appraisal of Gene Expression‐Based Classifiers for Neuropsychiatric Disorders: A Meta‐Regression

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT A substantial body of research examines the potential of gene‐expression‐based biomarkers for diagnosing and selecting treatments for neuropsychiatric disorders, yet no clear consensus has been reached regarding the influence of controllable factors such as study design and model selection on the performance of gene‐expression‐based ...
Ali Razavi, Brittany Arensman, Eric J. Barnett, Leo A. Lee, Stephen V. Faraone, Stephen J. Glatt, Jonathan L. Hess   +6 more
wiley   +1 more source

Towards precision psychiatry: Metabolomics identifies three biological subtypes of depression.

PLOS Digital Health
Depression is clinically and biologically heterogeneous, mandating classification strategies for personalized medicine. This study explored depression subtypes using metabolomics data from the UK Biobank and validated the subtypes in the Whitehall II ...
Simeng Ma, Zhaowen Nie, Mengyuan Zhang, Junhua Mei, Enqi Zhou, Zhiyi Hu, Honggang Lv, Qian Gong, Gaohua Wang, Huiling Wang, Bo Du, Jun Yang, Zhongchun Liu   +12 more
doaj   +1 more source