Results 121 to 130 of about 3,684,448 (359)

Electrosynthesis of Bioactive Chemicals, From Ions to Pharmaceuticals

Advanced Functional Materials, EarlyView.
This review discusses recent advances in electrosynthesis for biomedical and pharmaceutical applications. It covers key electrochemical materials enabling precise delivery of ions and small molecules for cellular modulation and disease treatment, alongside catalytic systems for pharmaceutical synthesis.
Gwangbin Lee, Sojin Kim, Myeongeun Lee, Kyoungsuk Jin, Jimin Park   +4 more
wiley   +1 more source

The many roads to psychosis: recent advances in understanding risk and mechanisms. [PDF]

, 2018
Schizophrenia is a chronic and severe mental illness which frequently leads to substantial lifelong disability. The past five years have seen major progress in our understanding of the complex genetic architecture of this disorder.
Bearden, Carrie E, Forsyth, Jennifer K
core  

Atypical neural responses to vocal anger in attention-deficit/hyperactivity disorder [PDF]

, 2014
Background Deficits in facial emotion processing, reported in attention-deficit/hyperactivity disorder (ADHD), have been linked to both early perceptual and later attentional components of event-related potentials (ERPs).
Banaschewski, Banaschewski, Banse, Barry, Biederman, Blackburn, Bostanov, Broyd, Bruckmann, Chronaki, Chronaki, Corbett, Corwin, Cullum, D'Agati, Dennis, Dien, Eimer, Fairchild, Goodman, Hogan, Ibáñez, Iredale, Jaaskelainen, Johnston, Johnstone, Johnstone, Johnstone, Konrad, Korpilahti, Kosslyn, Köchel, Köchel, Loiselle, Maurage, Mueller, Nelson, Norvilitis, Oades, Olincy, Pang, Pinheiro, Pinheiro, Putman, Sander, Schirmer, Semlitsch, Shaffer, Shapiro, Shaw, Sonuga-Barke, Stringaris, Toivonen, Uekermann, Wechsler, Williams, Woldorff, Woodman, Wunderlich, Zambelli   +59 more
core   +2 more sources

Astrocyte‐Guided Maturation of Neural Constructs in a Modular Biosynthetic Hydrogel for Biohybrid Neurotechnologies

Advanced Functional Materials, EarlyView.
A modular biosynthetic PVA–gelatin hydrogel crosslinked via visible‐light thiol‐ene chemistry is engineered as a coating for neural electrodes. Optimizing matrix composition and mechanical properties enables the hydrogel to support astrocytic populations that guide neural differentiation and functional maturation.
Martina Genta, Sofia Peressotti, Roberto Portillo‐Lara, Josef Goding, Rylie Green   +4 more
wiley   +1 more source

Concepts of mental disorders in the United Kingdom : Similarities and differences between the lay public and psychiatrists [PDF]

, 2019
BACKGROUND: The lay public often conceptualise mental disorders in a different way to mental health professionals, and this can negatively impact on outcomes when in treatment.
Ben Butlin, Cooper R., Dunn S., Field A., Furnham A., Jorm A. F., Keith Laws, Matthew D Broome, McCrone P., Rebecca Read, Shivani Sharma, Sullivan P. F., Tabachnick B. G., Vossler A.   +13 more
core   +2 more sources

The World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for the Biological Treatment of Bipolar Disorders: Update 2012 on the long-term treatment of bipolar disorder

World Journal of Biological Psychiatry, 2013
Objectives. These guidelines are based on a first edition that was published in 2004, and have been edited and updated with the available scientific evidence up to October 2012.
H. Grunze, E. Vieta, G. Goodwin, C. Bowden, R. Licht, H. Möller, S. Kasper   +6 more
semanticscholar   +1 more source

From In‐Silico Optimized Microfabrication to Experimental Validation: Engineering a Tridimensional Epi‐Intraneural Interface

Advanced Functional Materials, EarlyView.
An epi‐intraneural interface is developed through in silico optimization and a novel tridimensional microfabrication pipeline. The device integrates penetrating and epineural contacts on a flexible substrate. Mechanical, electrochemical, and in vivo testing in rat and pig reveal robust implantation, low‐threshold activation, and site‐dependent ...
Federico Ciotti, Andrea Cimolato, Noemi Gozzi, Pietro Palopoli, Luca Brugnoli, Natalija Katic Secerovic, Rebecca Gallivan, Alexander Shokurov, Carlo Menon, Johannes Weichart, Ignacio Delgado‐Martinez, Weiguo Song, Stavros Zanos, Xavier Navarro, Stanisa Raspopovic   +14 more
wiley   +1 more source

DNA methylation at the DAT promoter and risk for psychopathology. Intergenerational transmission between school-age youths and their parents in a community sample [PDF]

, 2018
Background: The effect of gene polymorphisms and promoter methylation, associated with maladaptive developmental outcomes, vary depending on environmental factors (e.g., parental psychopathology).
Claudio D’Addario, Claudio D’Addario, Eleonora Marzilli, Esterina Pascale, Giulia Ballarotto, Luca Cerniglia, Renata Tambelli, Silvia Cimino, Walter Adriani, Walter Adriani   +9 more
core   +2 more sources

Cortical Response to Acute Implantation of the Utah Optrode Array in Macaque Cortex

Advanced Healthcare Materials, EarlyView.
Delivering light deep into the brain over a large volume while causing minimal tissue damage is a major challenge for non‐human primate optogenetics. This study evaluates Utah Optrode Array designs in vivo, revealing how changes in shank geometry, surface texture, and insertion parameters minimize acute damage—offering a path toward high‐precision ...
Adrián Villamarin‐Ortiz, Christopher F. Reiche, Frederick Federer, Andrew M. Clark, John D. Rolston, Cristina Soto‐Sánchez, Eduardo Fernandez, Steve Blair, Alessandra Angelucci   +8 more
wiley   +1 more source

45 years German Society of Biological Psychiatry (DGBP). [PDF]

J Neural Transm (Vienna), 2023
Riederer P, Kircher T, Juckel G, Domschke K, Schneider A, Deckert J, Falkai P.   +6 more
europepmc   +1 more source