Results 61 to 70 of about 795,248 (355)

The World Journal of Biological Psychiatry [PDF]

The World Journal of Biological Psychiatry, 2009
Dear Colleagues, It is my great pleasure to present to you the World Journal of Biological Psychiatry, vol 11, issue 2, section 2.As one of the leading journals in the field, the World Journal of B...
openaire   +5 more sources

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

The computational psychiatry of reward: Broken brains or misguided minds?

Frontiers in Psychology, 2015
Research into the biological basis of emotional and motivational disorders is in danger of riding roughshod over a patient-centred psychiatry and falling into the dualist errors of the past, i.e. by treating mind and brain as conceptually distinct.
Michael eMoutoussis, Giles eStory, Ray eDolan, Ray eDolan   +3 more
doaj   +1 more source

Break-up and Recovery of Harmony between Direct and Indirect Pathways in The Basal Ganglia; Huntington's Disease and Treatment [PDF]

arXiv, 2023
The basal ganglia (BG) in the brain exhibit diverse functions for motor, cognition, and emotion. Such BG functions could be made via competitive harmony between the two competing pathways, direct pathway (DP) (facilitating movement) and indirect pathway (IP) (suppressing movement).
arxiv  

Expanding the Reach of Biological Psychiatry with Biological Psychiatry: Cognitive Neuroscience and Neuroimaging [PDF]

Biological Psychiatry, 2015
Over the past decade, the application of the tools and constructs of cognitive neuroscience to psychopathology research has evolved from a specialized niche area in the field to the dominant approach in clinical neuroscience. The development and widespread availability of magnetic resonance imaging and positron emission tomography scanners and other ...
openaire   +2 more sources

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Multivariate analyses of molecular genetic associations between childhood psychopathology and adult mood disorders and related traits

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, Volume 192, Issue 1-2, Page 3-12, January-March 2023., 2023
Abstract Ubiquitous associations have been detected between different types of childhood psychopathology and polygenic risk scores based on adult psychiatric disorders and related adult outcomes, indicating that genetic factors partly explain the association between childhood psychopathology and adult outcomes. However, these analyses in general do not
Wonuola A. Akingbuwa, Anke R. Hammerschlag, Andrea G. Allegrini, Hannah Sallis, Ralf Kuja‐Halkola, Kaili Rimfeld, Paul Lichtenstein, Sebastian Lundstrom, Marcus R. Munafò, Robert Plomin, Michel G. Nivard, Meike Bartels, Christel M. Middeldorp   +12 more
wiley   +1 more source

Fundamental concepts of phenomenology and descriptive psychopathology

Open Journal of Psychiatry and Allied Sciences, 2017
For a better understanding of what psychiatry is all about, the importance and stronghold of phenomenology and descriptive psychopathology in psychiatry has never been overstated. Biological psychiatry has accumulated enough evidences of mental illnesses
Debajit Gogoi
doaj   +1 more source

Computational Psychiatry in Borderline Personality Disorder [PDF]

Current Behavioral Neuroscience Reports, March 2017, Vol 4, Issue 1, pp31-40, 2017
Purpose of review: We review the literature on the use and potential use of computational psychiatry methods in Borderline Personality Disorder. Recent findings: Computational approaches have been used in psychiatry to increase our understanding of the molecular, circuit, and behavioral basis of mental illness.
arxiv   +1 more source

A study of psychiatrists’ concepts of mental illness [PDF]

, 2008
Background: There are multiple models of mental illness that inform professional and lay understanding. Few studies have formally investigated psychiatrists' attitudes.
Bowker, Brown, Clare, Cooper, Cutting, E. Antonova, Foucault, G. S. Owen, Gellner, Ghaemi, Good, Horwitz, Kleinman, Lewis, M. Broome, Meyer, Q. Deeley, R. Harland, R. Murray, S. Landau, Sandler, Thornicroft, Tyrer   +22 more
core   +4 more sources