CYP2C19 polymorphisms and outcomes of Escitalopram treatment in Brazilians with major depression
Heliyon, 2020 Escitalopram (ESC), a selective serotonin reuptake inhibitor indicated for the treatment of depression and anxiety disorders, is primarily metabolized by cytochrome P450 (CYP) 2C19, which is a highly polymorphic enzyme known to cause inter-individual ...
Rodrigo Bernini de Brito +1 more
doaj +1 more source
The many roads to psychosis: recent advances in understanding risk and mechanisms. [PDF]
, 2018 Schizophrenia is a chronic and severe mental illness which frequently leads to substantial lifelong disability. The past five years have seen major progress in our understanding of the complex genetic architecture of this disorder.
Bearden, Carrie E, Forsyth, Jennifer K
core
Anorexia nervosa and reproduction: connecting brain to gonads [PDF]
, 2020 Anorexia nervosa (AN) is a psychiatric disorder that predominantly affects young women and is characterized by low caloric intake and a major dissatisfaction with one’s body image.
Ciobanu, Corina +3 more
core +2 more sources
Concepts of mental disorders in the United Kingdom : Similarities and differences between the lay public and psychiatrists [PDF]
, 2019 BACKGROUND: The lay public often conceptualise mental disorders in a different way to mental health professionals, and this can negatively impact on outcomes when in treatment.
Ben Butlin +13 more
core +2 more sources
A Primer on Integral Theory and Its Application to Mental Health Care
Global Advances in Health and Medicine, 2020 Contemporary psychiatry has become increasingly focused on biological treatments. Many critics claim that the current paradigm of psychiatry has failed to address the escalating mental health-care needs of our communities and may even be contributing to ...
James D Duffy MD, FANPA, FAAHPM, DABMA
doaj +1 more source
, 2011 The Jefferson Journal Award has been established to honor the best paper submitted during each calendar year to the Jefferson Journal of Psychiatry: A Resident Publication.
core +1 more source
Clinical and Translational NeuroscienceOn behalf of the SFCNS, Swiss Federation of Clinical Neuro-Societies, we are pleased to present the Abstracts of the 6th SFCNS Congress, which will be held in Lausanne, Switzerland, 29–31 October 2025.
Swiss Federation of Clinical Neuro-Societies (SFCNS)
doaj +1 more source
Transcriptomic signatures of neuronal differentiation and their association with risk genes for autism spectrum and related neuropsychiatric disorders. [PDF]
, 2016 Genes for autism spectrum disorders (ASDs) are also implicated in fragile X syndrome (FXS), intellectual disabilities (ID) or schizophrenia (SCZ), and converge on neuronal function and differentiation. The SH-SY5Y neuroblastoma cell line, the most widely
Chiocchetti, AG +10 more
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Phenomenological Psychopathology and Psychiatric Classification [PDF]
, 2019 In this chapter, I provide an overview of phenomenological approaches to psychiatric classification. My aim is to encourage and facilitate philosophical debate over the best ways to classify psychiatric disorders.
Fernandez, Anthony Vincent
core
DNA methylation at the DAT promoter and risk for psychopathology. Intergenerational transmission between school-age youths and their parents in a community sample [PDF]
, 2018 Background: The effect of gene polymorphisms and promoter methylation, associated with maladaptive developmental outcomes, vary depending on environmental factors (e.g., parental psychopathology).
Claudio D’Addario +9 more
core +2 more sources