Results 81 to 90 of about 3,829,242 (325)

Identifying biological markers for improved precision medicine in psychiatry

Molecular Psychiatry, 2019
Mental disorders represent an increasing personal and financial burden and yet treatment development has stagnated in recent decades. Current disease classifications do not reflect psychobiological mechanisms of psychopathology, nor the complex interplay
E. Quinlan, T. Banaschewski, G. Barker, A. Bokde, U. Bromberg, C. Büchel, S. Desrivières, H. Flor, V. Frouin, H. Garavan, A. Heinz, R. Brühl, J. Martinot, M. Paillère Martinot, F. Nees, D. Orfanos, T. Paus, L. Poustka, S. Hohmann, M. Smolka, J. Fröhner, H. Walter, R. Whelan, G. Schumann   +23 more
semanticscholar   +1 more source

Histopathological Evidence of Neurodegenerative Pathology in Epilepsy: A Systematic Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Epilepsy affects > 50 million people worldwide and is associated with a disproportionate burden of cognitive impairment. Emerging evidence suggests that neurodegenerative proteinopathies, particularly hyperphosphorylated tau (p‐tau) and amyloid‐β (Aβ), may contribute to cognitive dysfunction in people with epilepsy (PWE), even in the absence ...
Syeda Amrah Hashmi, Aleksander Luniewski, Vanessa Smith, Matthew McCord, Jaideep Kapur, Mark Quigg, Catherine Joshua, Ifrah Zawar   +7 more
wiley   +1 more source

ENIGMA-Relatives - Brain Volumes in First-Degree Relatives of Schizophrenia and Bipolar Patients [PDF]

, 2017
72nd Annual Scientific Convention and Meeting of the Society-of-Biological-Psychiatry (SOBP) -- MAY 18-20, 2017 -- San Diego, CASoc Biol ...
Bramon, Elvira, Schofield, Peter, Gonul, Ali Saffet, Janice Fullerton, Roberts, Gloria, Lei Wang, Oliver Gruber, Di Giorgio, Annabella, Paul Thompson, Hilleke Hulshoff Pol, Tomas Hajek, Hajek, Tomas, Wiepke Cahn, Sonja de Zwarte, René Kahn, Alpert, Kathryn, Thompson, Paul, Glahn, David, Anja Richter, Theo van Erp, de Zwarte, Sonja, Pol, Hilleke Hulshoff, Neeltje van Haren, Gloria Roberts, Fatma Simsek, David Glahn, Hillegers, Manon, Xavier Caseras, Murray, Robin, Philip Mitchell, Alda, Martin, Bonvino, Aurora, Scott Fears, Turner, Jessica, Peter Schofield, Annabella Di Giorgio, Mehmet Cagdas Eker, Robin Murray, Ali Saffet Gonul, Kathryn Alpert, Rachel Brouwer, Martin Alda, null group ENIGMA-Relatives Group, Ole Andreassen, Mitchell, Philip, Andreassen, Ole, Brouwer, Rachel, Carrie Bearden, Eker, Mehmet Cagdas, Simsek, Fatma, Bearden, Carrie, van Erp, Theo, Elvira Bramon, Kahn, Rene, Cahn, Wiepke, Fullerton, Janice, Kane, Fergus, Fears, Scott, Gruber, Oliver, Manon Hillegers, Fergus Kane, Bertolino, Alessandro, Richter, Anja, Alessandro Bertolino, van Haren, Neeltje, Caseras, Xavier, Wang, Lei, Jessica Turner, Aurora Bonvino   +68 more
core   +1 more source

Stage‐Dependent β‐Synuclein Links MRI and Cognitive Decline in Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Synaptic degeneration drives cognitive decline in Alzheimer's disease (AD), but synaptic biomarkers are scarce. Brain‐enriched β‐synuclein emerged as a synaptic damage marker. We investigated its diagnostic, prognostic, and structural correlates across the AD continuum.
Ulaş Ay, Merve Alaylioglu, Erdi Sahin, Sanem Sultan Yoruk Oner, Gulce Iskan, Gulce Cosku Yilmaz Cakan, Gozde Kizilates‐Evin, Emre Hari, Elif Kurt, Erdinc Dursun, Basar Bilgic, Hasmet Hanagasi, Hakan Gurvit, Tamer Demiralp, Duygu Gezen‐Ak, Bedia Samanci   +15 more
wiley   +1 more source

Mucocutaneous Disease Activity and Damage Accrual in Systemic Lupus Erythematosus: Analyses From the Asia‐Pacific Lupus Collaboration Longitudinal Cohort Study

Arthritis Care &Research, EarlyView.
Objective This research article aims to describe the prevalence, associations, and health‐related quality of life (HRQoL) impact of mucocutaneous features of systemic lupus erythematosus (SLE). Methods Data from the Asia‐Pacific Lupus Collaboration cohort were analyzed (2013–2021).
Amanda M. Saracino, Yanjie Hao, Dylan Hansen, Yi‐Hsing Chen, Alberta Hoi, Vera Golder, Jiacai Cho, Aisha Lateef, Worawit Louthrenoo, Laniyati Hamijoyo, Shue Fen Luo, Yeong‐Jian Jan Wu, Sandra Navarra, Leonid Zamora, Chak Sing Lau, Shirley Chan, Zhanguo Li, Hai‐hong Yao, Sargunan Sockalingam, B. M. D. B. Basnayake, Yasuhiro Katsumata, Masayoshi Harigai, Zhuoli Zhang, Jun Kikuchi, Yuko Kaneko, Tsutomu Takeuchi, Madelynn Chan, Sang‐Cheol Bae, Fiona Goldblatt, Sean O'Neill, Geraldine Hassett, Kristine Ng, Nicola Tugnet, Mark Sapsford, Yih Jia Poh, Michael Tee, Cherica Tee, Naoaki Ohkubo, Yoshiya Tanaka, Rangi Kandane‐Rathnayake, Eric Morand, Shereen Oon, Mandana Nikpour   +42 more
wiley   +1 more source

The time of prenatal stress exposure differentially alter behaviors in male and female offspring [PDF]

, 2011
The 10th World Congress of Biological Psychiatry (WFSBP 2011), Prague, Czech Republic, 29 May-2 June ...
Chen, M, McAlonan, G, Ao, L, Rudd, JA, Lu, G, Jiu, T, Li, Q   +6 more
core  

Effect of psilocybin on marble burying in ICR mice: role of 5-HT1A receptors and implications for the treatment of obsessive-compulsive disorder

Translational Psychiatry, 2023
Preliminary clinical findings, supported by preclinical studies employing behavioral paradigms such as marble burying, suggest that psilocybin may be effective in treating obsessive-compulsive disorder.
Sandeep Singh, Alexander Botvinnik, Orr Shahar, Gilly Wolf, Corel Yakobi, Michal Saban, Adham Salama, Amit Lotan, Bernard Lerer, Tzuri Lifschytz   +9 more
doaj   +1 more source

A Geometrically Transient Platform for Bioelectronic Implants

Advanced Materials, EarlyView.
Minimally invasive bioelectronic implants often compromise performance for smaller sizes. To resolve this optimization dilemma, a wireless bioelectronic implant with a transient geometry is introduced (MiFi). The origami‐inspired device miniaturizes up to sixfold for syringe insertion and autonomously unfolds post‐implantation.
Selin Olenik, John D. Goodwin, Atharv Naik, Philip Coatsworth, Ioi Chit Cheung, Farbod Amirghasemi, Anies Sohi, Ehsan Abedi, Tayeb Tadlaoui, Maral P. S. Mousavi, Andriy S. Kozlov, Victoria Salem, Andrew S. Cowburn, Firat Guder   +13 more
wiley   +1 more source

Time of prenatal stress challenge determines gender differences in expression of interleukin 18 in the ventral hippocampus of rats [PDF]

, 2011
The 10th World Congress of Biological Psychiatry (WFSBP 2011), Prague, Czech Republic, 29 May-2 June ...
Chen, M, Ng, TB, McAlonan, G, Wong, JH, Ao, L, Rudd, JA, Lu, G, Jiu, T, Li, Q   +8 more
core  

A Primer on Integral Theory and Its Application to Mental Health Care

Global Advances in Health and Medicine, 2020
Contemporary psychiatry has become increasingly focused on biological treatments. Many critics claim that the current paradigm of psychiatry has failed to address the escalating mental health-care needs of our communities and may even be contributing to ...
James D Duffy MD, FANPA, FAAHPM, DABMA
doaj   +1 more source