Results 61 to 70 of about 3,178,330 (288)

Safety and Efficacy of GLP‐1 Receptor Agonists in Adults With Epilepsy, Obesity, and Type 2 Diabetes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Managing obesity in patients with epilepsy is complicated by the weight‐gaining properties of essential antiseizure medications (ASMs) such as valproate and pregabalin. We evaluated the safety and efficacy of initiating glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) in this population.
Hyoshin Son, Inyoung Hwang, Sang Won Lee, Yun Kim   +3 more
wiley   +1 more source

Cortical Timing Biomarkers of Psychomotor Dysfunction in Depressive Disorder: A Cross-Validated Study

Psychiatry International
Background: Major Depressive Disorder (MDD) is increasingly recognized as involving psychomotor slowing and impaired cortical timing. Objective vibrotactile assessments can quantify sensory and cognitive integration, potentially identifying mechanistic ...
Mayra Evelise dos Santos, Kariny Realino Ferreira, Sérgio Fonseca, Gabriela Lopes Gama, Michelle Almeida Barbosa, Alexandre Carvalho Barbosa   +5 more
doaj   +1 more source

Indianizing psychiatry – A critique

Indian Journal of Psychiatry, 2018
The issue of culture in Indian psychiatry has endured increasing neglect with the burgeoning biological paradigm. This viewpoint debates and demystifies the connotation of “culture” in mainstream psychiatry.
Anindya Das, Urvashi Rautela
doaj   +1 more source

Subjective Cognitive Concerns and Cognitive Trajectories in Parkinson's Disease: Biomarker Impact

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the relationship of subjective cognitive concerns (SCC) with biomarkers of Alzheimer's disease (AD), neurodegeneration, and Parkinson's disease (PD) and domain‐specific cognitive trajectories among cognitively unimpaired persons with de novo PD. Method Cognitively unimpaired participants with SCC (n = 294) and without SCC (
Francesca V. Lopez, Fareshte Erani, Katherine J. Bangen, David G. Coughlin, Douglas Galasko, Kelsey R. Thomas   +5 more
wiley   +1 more source

An ode to the silver jubilee conference of Indian Association for Social Psychiatry: Too long a time to reach here? Or too short perhaps?

Indian Journal of Social Psychiatry, 2018
Standing on the vantage point of the Silver Jubilee National Conference of the Indian Association for Social Psychiatry, what have we learned, achieved, accomplished? We held a large number of conferences, have made a number of collaborations.
Vijoy K Varma
doaj   +1 more source

ENIGMA-Relatives - Brain Volumes in First-Degree Relatives of Schizophrenia and Bipolar Patients

, 2017
72nd Annual Scientific Convention and Meeting of the Society-of-Biological-Psychiatry (SOBP) -- MAY 18-20, 2017 -- San Diego, CASoc Biol ...
Bramon, Elvira, Schofield, Peter, Gonul, Ali Saffet, Janice Fullerton, Roberts, Gloria, Lei Wang, Oliver Gruber, Di Giorgio, Annabella, Paul Thompson, Hilleke Hulshoff Pol, Tomas Hajek, Hajek, Tomas, Wiepke Cahn, Sonja de Zwarte, René Kahn, Alpert, Kathryn, Thompson, Paul, Glahn, David, Anja Richter, Theo van Erp, de Zwarte, Sonja, Pol, Hilleke Hulshoff, Neeltje van Haren, Gloria Roberts, Fatma Simsek, David Glahn, Hillegers, Manon, Xavier Caseras, Murray, Robin, Philip Mitchell, Alda, Martin, Bonvino, Aurora, Scott Fears, Turner, Jessica, Peter Schofield, Annabella Di Giorgio, Mehmet Cagdas Eker, Robin Murray, Ali Saffet Gonul, Kathryn Alpert, Rachel Brouwer, Martin Alda, null group ENIGMA-Relatives Group, Ole Andreassen, Mitchell, Philip, Andreassen, Ole, Brouwer, Rachel, Carrie Bearden, Eker, Mehmet Cagdas, Simsek, Fatma, Bearden, Carrie, van Erp, Theo, Elvira Bramon, Kahn, Rene, Cahn, Wiepke, Fullerton, Janice, Kane, Fergus, Fears, Scott, Gruber, Oliver, Manon Hillegers, Fergus Kane, Bertolino, Alessandro, Richter, Anja, Alessandro Bertolino, van Haren, Neeltje, Caseras, Xavier, Wang, Lei, Jessica Turner, Aurora Bonvino   +68 more
core   +1 more source

Cerebrospinal Fluid Over Plasma Links Analytes to Cognitive Decline in Older Adults at Risk for Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To identify inflammatory analytes in cerebrospinal fluid (CSF) and plasma associated with cognitive decline in cognitively normal (CN) older adults at risk for Alzheimer's disease (AD). Methods In a longitudinal study of 118 CN older adults (65–80 years, 54% APOE ε4, 26% preclinical AD), 1331 CSF and 1501 plasma analytes were ...
Jagan A. Pillai, Audrey Zhu, Chunxuan Ma, Ming Wang, Yifan Yang, Lynn M. Bekris, Maria Khrestian, Frank P. DiFilippo, Mikhail Nasrallah, Aaron Burberry, James B. Leverenz, Yuan Hou, Feixiong Cheng, Stephen M. Rao   +13 more
wiley   +1 more source

The Association of Amyloid‐β and Tau With Synaptic Dysfunction in Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the relative contributions of amyloid and tau to synaptic dysfunction in Alzheimer's disease (AD). Methods We included 109 cognitively unimpaired and impaired individuals from the Geneva Memory Center with available CSF synaptic biomarkers (neurogranin, SNAP‐25, GAP‐43). Participants were stratified according to amyloid (A)
Fausto Roveta, Augusto J. Mendes, Valentina Garibotto, Cecilia Boccalini, Aurelien Lathuiliere, Innocenzo Rainero, Elisa Rubino, Henrik Zetterberg, Nicholas J. Ashton, Federica Ribaldi, Giovanni B. Frisoni, for the Alzheimer's Disease Neuroimaging Initiative   +11 more
wiley   +1 more source

Clinical Variability and Genotype Driven Outcomes in an International Cohort of 14 Pediatric FIG4 Patients

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Biallelic FIG4 variants classically cause distinct conditions characterized by peripheral neuropathy (Charcot‐Marie‐Tooth disease type 4J) or skeletal dysplasia (Yunis‐Varón syndrome). However, central nervous system involvement is increasingly recognized. The prevalence and specific characteristics of movement disorders within FIG4‐
Andrea Gangfuß, Vykuntaraju K. Gowda, Daniel Natera‐de Benito, Pinki Munot, Maria Vanegas, Alejandra Darling, Constanze Reutlinger, Laura Carrera‐Garcia, Gilbert Wunderlich, Heike Kölbel, Burkhard Stüve, David Muhmann, Lucía Monfort Belenguer, Diana‐Gabriela Barca, Viveka Santhosh Reddy C, Varunvenkat M. Srinivasan, Cristina Molina Anguita, Heinz Jungbluth, Hormos Salimi Dafsari, Thomas Rossor, Johann Böhm, Ulrike Schara‐Schmidt, Andreas Roos   +22 more
wiley   +1 more source

Associations Between Biomarkers of Alzheimer's Disease and Sleep in Cognitively Unimpaired Older Adults

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Sleep disturbances have been implicated as a risk factor for developing Alzheimer's disease (AD), but evidence linking plasma AD biomarkers to sleep in cognitively unimpaired individuals remains limited. The present study examined associations between evening, morning, and overnight changes in plasma AD biomarkers and measures of ...
Cornelia Sauter, Hans Dorn, Julian Hellmann‐Regen, Ana Bueno‐Lopez, Verena van Ginneken, Heidi Danker‐Hopfe   +5 more
wiley   +1 more source