Results 61 to 70 of about 3,829,242 (325)

Prodromal Lewy Body Disorder Features in REM Sleep Behavior Disorder With Biomarker‐Defined Synucleinopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid eye movement sleep behavior disorder (iRBD) is a prodromal state for Lewy body disorders and exhibits biological heterogeneity that may influence clinical expression and progression. We examined clinical features in individuals with iRBD and biomarker‐defined synucleinopathy.
Daniel Weintraub, Michele K. York, Roseanne Dobkin, Anuprita R. Nair, Ryan Kurth, David‐Erick Lafontant, Chelsea Caspell‐Garcia, Roy N. Alcalay, Ethan G. Brown, Lana M. Chahine, Christopher Coffey, Tatiana Foroud, Douglas Galasko, Karl Kieburtz, Kenneth Marek, Kalpana Merchant, Brit Mollenhauer, Kathleen L. Poston, Andrew Siderowf, Cristina Simonet, Tanya Simuni, Caroline M. Tanner, Thomas F. Tropea, Aleksandar Videnovic, The Parkinson's Progression Markers Initiative   +24 more
wiley   +1 more source

Measuring Earwax Cortisol Concentration using a non-stressful sampling method

Heliyon, 2020
Background: “Short-term” samples are not the most appropriate for reflecting chronic cortisol concentration. Although hair is used for reflecting the systemic level of this hormone, its use as a “long-term” measure appears clinically problematic.
Andres Herane-Vives, Lorena Ortega, Rodrigo Sandoval, Allan H. Young, Anthony Cleare, Susana Espinoza, Alexander Hayes, Jan Benöhr   +7 more
doaj   +1 more source

World Federation of Societies of Biological Psychiatry (WFSBP) consensus statement on candidate biomarkers for anorexia nervosa

World Journal of Biological Psychiatry
Objectives This World Federation of Societies of Biological Psychiatry (WFSBP) consensus paper aims to summarise and evaluate the published study results on objectively measurable biological markers associated with anorexia nervosa (AN).
H. Himmerich, J. Keeler, Joseph A. King, S. Ehrlich, Lisa-Katrin Kaufmann, C. Bulik, S. Cohen-Woods, Tracey D Wade, Howard Steiger, Linda Booij, P. Monteleone, G. Cascino, A. Monteleone, Ulrich Cuntz, Ulrich Voderholzer, S. A. Tessema, Y. Lewis, Magnus Sjögren, Johannes Hebebrand, Jochen Seitz, M. Tyszkiewicz-Nwafor, O. Karpenko, H. Mutwalli, S. Fetissov, Isabelle Mack, N. Dhopatkar, Sabrina Moerkl, Carol Kan, M. M. Uribe, Kazuhiro Yoshiuchi, Nadine Abuobeid, Dimitrios Kapogiannis, Daniel Stein, S. Bektas, Daniel J Müller, P. Gorwood, P. Duriez, Chloé Tezenas du Montcel, E. Paszyńska, Susan L. McElroy, W. D. Wranik, F. Fernández-Aranda, Philip S Mehler, H. Papežová, R. Roubalova, P. Prochazkova, Rebecca Morris, Piotr Lewczuk, C. Hiemke, Michael Berk, A. Karwautz, J. Treasure, S. Kasper   +52 more
semanticscholar   +1 more source

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source

Deep brain stimulation in major depression: Plastic changes of 5-hydroxytryptamine neurons [PDF]

, 2015
Refers to: Antidepressant-like Effects of Cortical Deep Brain Stimulation Coincide With Pro-neuroplastic Adaptations of Serotonin Systems. Biological Psychiatry 76(3): 203-212 (2014)Referred to by: Erratum.
Artigas, Francesc
core   +1 more source

Evaluation of the effect of insulin sensitivity-enhancing lifestyle- and dietary-related adjuncts on antidepressant treatment response: A systematic review and meta-analysis

Heliyon, 2020
Background: Depression is associated with insulin resistance (IR). However, the potential beneficial effect, on antidepressant treatment response, of adjunctive therapy with insulin sensitivity-enhancing lifestyle and dietary interventions (exercise ...
Olaitan J. Jeremiah, Gráinne Cousins, Fiona Boland, Brian P. Kirby, Benedict K. Ryan   +4 more
doaj   +1 more source

Impact of Plasma p‐tau181 on Cognition, Motor Phenotypes, and Disease Course in ALS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Phosphorylated tau181 (p‐tau181), an Alzheimer's disease biomarker, was recently evaluated in amyotrophic lateral sclerosis (ALS). We investigated plasma p‐tau181 in 202 ALS/ALS‐FTD patients and 94 healthy controls, assessing cognitive performance, motor function, and longitudinal dynamics.
Elisabeth Kasper, Annaliis Lehto, Nina Nordmann, Oliver Peters, Julian Hellmann, Josef Priller, Eike Jakob Spruth, Gabor C. Petzold, Ina Vogt, Patrick Weydt, Sarah Bernsen, Elisabeth Dinter, Björn Falkenburger, René Günther, Emrah Düzel, Wenzel Glanz, Matthis Synofzik, Lukas Beichert, Annika Spottke, Michael Wagner, Frederic Brosseron, Matthias C. Schmid, Anja Schneider, Stefan Teipel, Johannes Prudlo, Andreas Hermann   +25 more
wiley   +1 more source

Sex‐Stratified Association of Regional Dopamine Transporter Binding With Disease Progression in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe, Keizo Sugaya, Kentaro Hayashi, Keiko Hino, Yasuhiro Nakata, Kota Bokuda, Toshio Shimizu, Kazushi Takahashi   +7 more
wiley   +1 more source

Genome-wide association study of major depressive disorder: new results, meta-analysis, and lessons learned [PDF]

, 2010
Major depressive disorder (MDD) is a common complex disorder with a partly genetic etiology. We conducted a genome-wide association study of the MDD2000+ sample (2431 cases, 3673 screened controls and >1 M imputed single-nucleotide polymorphisms (SNPs)).
D I Boomsma, Maclean, A. W., Sullivan, P.F., Sullivan, P F, G Willemsen, de Geus, E.J.C., D J Statham, Willemsen, G.; id_orcid, Gordon, SD, Penninx, BWJH, Smit, J H, Medland, S E, Maclean, A.W., S E Medland, Penninx, B. W. J. H., van den Oord, E J C G, Montgomery, G W, Pergadia, M L, Byrne, E.M., Heath, A.C., Martin, N.G., MacIntyre, Donald; id_orcid, Hickie, I.B., Statham, D.J., C M Middeldorp, E M Byrne, B W J H Penninx, Nyholt, D.R., J J Hottenga, J H Smit, A K Henders, Blackwood, D.H., Liu, J. Z., N G Martin, A W Maclean, Lewis, C.M., Montgomery, G. W., McGuffin, P, S D Gordon, McEvoy, B.P., MacIntyre, D J, McGhee, K A, P A F Madden, MacIntyre, D J; id_orcid, Pergadia, M. L., van den Oord, E.J., McEvoy, B P, Gordon, S.D., Martin, N. G., D H R Blackwood, P F Sullivan, De Geus, E. J. C., Montgomery, G.W., Hottenga, J.J., Hickie, I. B., McGhee, K.A., Medland, S. E., C M Lewis, J Z Liu, Gordon, S D, Smit, J. H., Boomsma, D. I., Hottenga, J. J., Smit, J.H., Middeldorp, C.M., Ripke, S., M L Pergadia, Hickie, I B, de Geus, E.J., Wray, NR, Van Den Oord, E. J. C. G., Wray, N. R., Blackwood, DHR, de Geus, E J C, Penninx, B.W., B P McEvoy, McGhee, K. A., Middeldorp, C. M., Byrne, E. M., McEvoy, B. P., Macgregor, S, E J C G van den Oord, Statham, D J, Heath, A C, Lewis, C. M., van den Oord, E.J.C.G., I B Hickie, Willemsen, G., Pergadia, M.L., Medland, S.E., Sullivan, P. F., Penninx, B.W.J.H., Heath, A. C., Maclean, AW, Nyholt, D. R., N R Wray, S Macgregor, MacIntyre, DJ, Boomsma, D.I., G W Montgomery, Lewis, C M, Henders, A K, Madden, P. A. F., Madden, P.A.F., Henders, A.K., Hottenga, J J, McGuffin, P., Boomsma, D I, Madden, P.A., de Geus, E.J.C.; id_orcid, Oord, E.J.C.G. van den, Henders, A. K., Wray, N R, Madden, P A F, E J C de Geus, Pergadia, ML, D R Nyholt, Maclean, A W, Ripke, S, A C Heath, Ripke, Stephan, MacIntyre, D. J., Geus, E.J.C. de, Blackwood, D. H. R., Statham, D. J., Penninx, B W J H, Macgregor, S., Gordon, S. D., McGhee, KA, D J MacIntyre, Nyholt, D R, Wray, N.R., Middeldorp, C M, Liu, J Z, S Ripke, K A McGhee, P McGuffin, Nyholt, DR, Willemsen, G, Boomsma, D.I.; id_orcid, Lewis, C. M.; id_orcid, Martin, N G, Blackwood, D H R, Liu, J.Z., Byrne, E M, MacIntyre, D.J.   +145 more
core   +1 more source

Mental Health Biobanks—A Systematic Review on the Prevalence, Creation, and Implementation of Mental Health Biobanks Globally

Psychiatry International, 2023
Biobanks are collections of human biological materials (biospecimens) alongside personal health information that are stored for scientific research.
Nitika S. Govind, Kerri M. Gillespie, Grace Branjerdporn   +2 more
doaj   +1 more source