Results 151 to 160 of about 73,850,713 (262)

Advancing Regulatory Adoption of New Approach Methodologies. [PDF]

open access: yesClin Pharmacol Ther
Florian J   +7 more
europepmc   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Referees for Volume 37, n. 1 of the Acta Scientiarium. Biological Sciences, 2015

open access: yes, 2015
The Editorial Board of Acta Scientiarum. Biological Sciences would like to thank the referees listed below for their critical appreciation of articles submitted for Volume 37, n. 1 (2015).
Biological Sciences, Acta Scientiarum.; Referees
core  

Pyridinium and related azinium salts in organic synthesis and medicinal chemistry. [PDF]

open access: yesRSC Adv
Mohammadi Mehr E   +6 more
europepmc   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

open access: yesFEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti   +5 more
wiley   +1 more source

The High Dispersion of Phenolic Concentration in the Seeds, Skins and Wines of <i>Vitis vinifera</i> L. Cultivars Limits Comparative Analysis and Varietal Categorization Under Heterogeneous Conditions. [PDF]

open access: yesAntioxidants (Basel)
López-Solís R   +8 more
europepmc   +1 more source

Using cell‐free RNA to identify B‐ and T‐cell clonality for diagnosis and monitoring of B‐ and T‐cell neoplasms

open access: yesFEBS Open Bio, EarlyView.
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar   +11 more
wiley   +1 more source

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