Development of small fluorescent probes for the analysis of autophagy kinetics
Summary: Autophagy is a dynamic process that degrades subcellular constituents, and its activity is measured by autophagic flux. The tandem proteins RFP-GFP-LC3 and GFP-LC3-RFP-LC3ΔG, which enable the visualization of autophagic vacuoles of different ...
Hajime Tajima Sakurai+9 more
doaj +1 more source
Automated design of gene circuits with optimal mushroom-bifurcation behavior
Summary: Recent advances in synthetic biology are enabling exciting technologies, including the next generation of biosensors, the rational design of cell memory, modulated synthetic cell differentiation, and generic multifunctional biocircuits.
Irene Otero-Muras+3 more
doaj +1 more source
The BioImage Archive - building a home for life-sciences microscopy data
Despite the huge impact of data resources in genomics and structural biology, until now there has been no central archive for biological data for all imaging modalities. The BioImage Archive is a new data resource at the European Bioinformatics Institute
Matthew Hartley+5 more
semanticscholar +1 more source
A new approach to teaching feedback [PDF]
The Control and Dynamical Systems (CDS) Department at the California Institute of Technology (Caltech) has revised its entry-level curriculum in dynamics, feedback, and control with the goals of updating the subject matter to include modern tools and ...
Cremean, Lars B.+3 more
core +1 more source
Fluorescein Derivatives as Fluorescent Probes for pH Monitoring along Recent Biological Applications
Potential of hydrogen (pH) is one of the most relevant parameters characterizing aqueous solutions. In biology, pH is intrinsically linked to cellular life since all metabolic pathways are implicated into ionic flows.
Florent Le Guern+4 more
semanticscholar +1 more source
Translating New Synthetic Biology Advances for Biosensing Into the Earth and Environmental Sciences
The rapid diversification of synthetic biology tools holds promise in making some classically hard-to-solve environmental problems tractable. Here we review longstanding problems in the Earth and environmental sciences that could be addressed using ...
Ilenne Del Valle+5 more
semanticscholar +1 more source
BioMet Toolbox 2.0: genome-wide analysis of metabolism and omics data [PDF]
Analysis of large data sets using computational and mathematical tools have become a central part of biological sciences. Large amounts of data are being generated each year from different biological research fields leading to a constant development of ...
Garcia-Albornoz, Manuel+5 more
core +1 more source
Appraisal of ozone as biologically active molecule and experimental tool in biomedical sciences
Ozone (O3) (CAS 10028-15-6) is a major air industrial pollutant and is well known for its very strong oxidative actions which affords the molecule its useful antimicrobial and deodorizing properties, but also its potential toxic effects. Knowledge of the activity and safety of ozone is important if its potential for use as a biologically active agent ...
Mokoena, Mmalebuso L.+3 more
openaire +5 more sources
Evolutionary Algorithms in a Bacterial Consortium of Synthetic Bacteria
At present, synthetic biology applications are based on the programming of synthetic bacteria with custom-designed genetic circuits through the application of a top-down strategy. These genetic circuits are the programs that implement a certain algorithm,
Sara Lledó Villaescusa+1 more
doaj +1 more source
PSYCHOLOGICAL AND PEDAGOGICAL INSTRUMENTS FOR THE TEACHER OF NATURE DISCIPLINES IN HIGHER MEDICAL EDUCATION [PDF]
The article considers the main psychological and pedagogical tools of the teacher in the field of fundamental training of applicants for higher medical education in the discipline “Medical and Biological Physics”.
Volodymyr I. Fediv+2 more
doaj +1 more source