Results 51 to 60 of about 1,815,049 (345)

Quantitative biology: where modern biology meets physical sciences [PDF]

, 2014
Quantitative methods and approaches have been playing an increasingly important role in cell biology in recent years. They involve making accurate measurements to test a predefined hypothesis in order to compare experimental data with predictions ...
Fai, Thomas G., Mazutis, Linas, Podolski, Marija, Sgro, Allyson E., Shekhar, Shashank, Zhu, Lian   +5 more
core   +2 more sources

Biological Toxins as the Potential Tools for Bioterrorism

International Journal of Molecular Sciences, 2019
Biological toxins are a heterogeneous group produced by living organisms. One dictionary defines them as “Chemicals produced by living organisms that have toxic properties for another organism”. Toxins are very attractive to terrorists for use in acts of
Edyta Janik, Michal Ceremuga, Joanna Saluk-Bijak, M. Bijak   +3 more
semanticscholar   +1 more source

Colib'read on galaxy : a tools suite dedicated to biological information extraction from raw NGS reads [PDF]

, 2016
Background: With next-generation sequencing (NGS) technologies, the life sciences face a deluge of raw data. Classical analysis processes for such data often begin with an assembly step, needing large amounts of computing resources, and potentially ...
Alves-Carvalho, Susete, Andrieux, Alexan, Cazaux, Bastien, Collin, Olivier, El Aabidine, Amal Zine, Lacroix, Vincent, Le Bras, Yvan, Lemaitre, Claire, Marchet, Camille, Miele, Vincent, Monjeaud, Cyril, Peterlongo, Pierre, Rivals, Eric, Sacomoto, Gustavo, Salmela, Leena, Uricaru, Raluca   +15 more
core   +3 more sources

Community development, implementation, and assessment of a NIBLSE bioinformatics sequence similarity learning resource.

PLoS ONE, 2021
As powerful computational tools and 'big data' transform the biological sciences, bioinformatics training is becoming necessary to prepare the next generation of life scientists. Furthermore, because the tools and resources employed in bioinformatics are
Adam J Kleinschmit, Elizabeth F Ryder, Jacob L Kerby, Barbara Murdoch, Sam Donovan, Nealy F Grandgenett, Rachel E Cook, Chamindika Siriwardana, William Morgan, Mark Pauley, Anne Rosenwald, Eric Triplett, William Tapprich   +12 more
doaj   +1 more source

Application of Graph Theory and Automata Modeling for the Study of the Evolution of Metabolic Pathways with Glycolysis and Krebs Cycle as Case Studies

Computation, 2023
Today, graph theory represents one of the most important modeling techniques in biology. One of the most important applications is in the study of metabolic networks. During metabolism, a set of sequential biochemical reactions takes place, which convert
Carlos De Las Morenas Mateos, Rafael Lahoz-Beltra   +1 more
doaj   +1 more source

Nano-imaging and its applications to biomedicine [PDF]

, 2011
Nanotechnology tools, such as Atomic Force Microscopy (AFM), are now becoming widely used in life sciences and biomedicine. AFM is a versatile technique that allows studying at the nanoscale the morphological, dynamic, and mechanical properties of ...
Adya, Ashok K., Canetta, Elisabetta
core   +2 more sources

Deep-tissue focal fluorescence imaging with digitally time-reversed ultrasound-encoded light. [PDF]

, 2012
Fluorescence imaging is one of the most important research tools in biomedical sciences. However, scattering of light severely impedes imaging of thick biological samples beyond the ballistic regime.
Dimarzio, Charles A, Judkewitz, Benjamin, Wang, Ying Min, Yang, Changhuei   +3 more
core   +3 more sources

Detecting periodicity in experimental data using linear modeling techniques [PDF]

, 1998
Fourier spectral estimates and, to a lesser extent, the autocorrelation function are the primary tools to detect periodicities in experimental data in the physical and biological sciences.
C. S. Burrus, G. Schwarz, H. Akaike, H. Tong, J. Rissanen, J. Theiler, J. Theiler, K. Judd, Kevin Judd, L. Aguirre, M. Small, M. Small, Michael Small, N. Nicholls, P. J. Brusil, V. Haggan   +15 more
core   +2 more sources

Developing ABEmax-NG with Precise Targeting and Expanded Editing Scope to Model Pathogenic Splice Site Mutations In Vivo

iScience, 2019
Summary: RNA splicing is related to many human diseases; however, lack of efficient genetic approaches to modulate splicing has prevented us from dissecting their functions in human diseases.
Shisheng Huang, Zhaodi Liao, Xiangyang Li, Zhen Liu, Guanglei Li, Jianan Li, Zongyang Lu, Yu Zhang, Xiajun Li, Xu Ma, Qiang Sun, Xingxu Huang   +11 more
doaj   +1 more source

Computational Tools for Discovering and Engineering Natural Product Biosynthetic Pathways

iScience, 2020
Natural products (NPs), also known as secondary metabolites, are produced in bacteria, fungi, and plants. NPs represent a rich source of antibacterial, antifungal, and anticancer agents.
Hengqian Ren, Chengyou Shi, Huimin Zhao
doaj   +1 more source