Results 71 to 80 of about 507,580 (307)
e-science and the semantic web: A symbiotic relationship [PDF]
, 2006 e-Science is scientific investigation performed through distributed global collaborations between scientists and their resources, and the computing infrastructure that enables this. Scientific progress increasingly depends on pooling know-how and results;
De Roure, David +16 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Interfacial Dynamics of Adsorption Layers as Supports for Biomedical Research and Diagnostics
Colloids and Interfaces, 2022 The input of chemical and physical sciences to life sciences is increasingly important. Surface science as a complex multidisciplinary research area provides many relevant practical tools to support research in medicine.
Eva Santini +8 more
doaj +1 more source
Interactive Computer Simulations as Pedagogical Tools in Biology Labs
, 2018 Student learning in biology may be impaired by instructional environments that emphasize technical methodology over analysis. We hypothesized that time gained by experimenting with accurate computer simulations could be used to engage students in ...
Bustos, Mauricio +3 more
core +1 more source
Tools and Principles for Microbial Gene Circuit Engineering [PDF]
, 2015 Synthetic biologists aim to construct novel genetic circuits with useful applications through rational design and forward engineering. Given the complexity of signal processing that occurs in natural biological systems, engineered microbes have the ...
Bradley, RW +6 more
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Annals of the Entomological Society of America, 2020 AbstractGlobal ecosystem functions, services, and commodities are increasingly threatened by biological invasions. As a result, there is an urgent need to manage invasive species through global collaborative research. We propose an ‘applied empirical framework’ (AEF) to aggressively confront the current global biological invasion crisis. The AEF builds
Gwylim S Blackburn +11 more
openaire +1 more source
iScience, 2018 Summary: The growing appetite of behavioral neuroscience for automated data production is prompting the need for new computational standards allowing improved interoperability, reproducibility, and shareability.
Jose Espinosa-Carrasco +5 more
doaj +1 more source
Soft X-ray Microscopy Techniques for Medical and Biological Imaging at TwinMic—Elettra
Applied Sciences, 2021 Progress in nanotechnology calls for material probing techniques of high sensitivity and resolution. Such techniques are also used for high-impact studies of nanoscale materials in medicine and biology.
Alessandra Gianoncelli +7 more
doaj +1 more source
BMS651: Bioinformatics / Faculty of Applied Sciences [PDF]
, 2020 This course is designed to equip students with the necessary theoretical knowledge and practical skills in bioinformatics. Students will be introduced to 3 major concepts in bioinformatics namely the resources, databases and tools. In resources, students
UiTM, Faculty of Applied Sciences
core