Results 91 to 100 of about 1,333,897 (299)
MicroorganismsThe type III secretion system (T3SS) is a nano-machine that allows Gram-negative bacteria to alter eukaryotic host biology by directly delivering effector proteins from the bacterial cytoplasm. Protein delivery based on the bacterial T3SS has been widely used in research in biology. This review explores recent advancements in the structure and function
Liyu Jia, Lihua Zhu
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Revista de Ensino de Bioquímica, 2017 A disciplina de bioquímica no geral é considerada de alto grau de dificuldade. Contudo, a aplicação de jogos lúdicos como metodologia de ensino vem se disseminando em várias disciplinas. “METABOLIC RIDE” é uma ferramenta de avaliação conceitual e de percepção para o ensino de bioquímica, visando rever conceitos difundidos em sala de aula, promovendo um
Gaeta, Henrique Hessel +6 more
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
On the context and presuppositions of Searle’s philosophy of society [PDF]
, 2018 In this article, I deal with Searle’s philosophy of society, the last step to complete his philosophical system. This step, however, requires an examination of the context and presuppositions, or default positions, that make possible the key concepts of ...
González, Rodrigo
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Data-driven modelling of biological multi-scale processes
, 2015 Biological processes involve a variety of spatial and temporal scales. A holistic understanding of many biological processes therefore requires multi-scale models which capture the relevant properties on all these scales.
Hasenauer, Jan +3 more
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Strong between-site variation in New Caledonian crows' use of hook-tool-making materials [PDF]
, 2016 The study was funded through a BBSRC David Phillips Fellowship (grants BB/G023913/1 and BB/G023913/2 to CR) and doctoral studentships from the BBSRC (BK), JASSO (SS), and the School of Biology, University of St Andrews (JvdW).Functional tool use requires
Klump, Barbara Christina +4 more
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COMPARISON OF BIG DATA ANALYTICS TOOLS: A BIOINFORMATICS CASE STUDY
FUUAST Journal of Biology, 2021 Due to the exponential growth of genomic sequence in the field of biological science, it becomes the immense challenge for biomedical practitioners and researchers to access and analyze it.
MUHAMMAD SHAHZAD, KAMRAN AHSAN
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The Relevance of Evolutionary Science For Economic Theory and Policy [PDF]
NSF’s “Dear Colleague Letter” reflects the widely perceived need to go beyond current economic theory in the formulation of public policy. At the same time, there is a profound lack of unity among the disciplines that comprise the behavioral, social, and
David Sloan Wilson, John M. Gowdy
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