Results 91 to 100 of about 4,020,279 (308)
Mutual Mobile Membranes with Timers
, 2009 A feature of current membrane systems is the fact that objects and membranes are persistent. However, this is not true in the real world. In fact, cells and intracellular proteins have a well-defined lifetime.
Bogdan Aman +4 more
core +2 more sources
Bounding the Equilibrium Distribution of Markov Population Models [PDF]
, 2010 Arguing about the equilibrium distribution of continuous-time Markov chains can be vital for showing properties about the underlying systems. For example in biological systems, bistability of a chemical reaction network can hint at its function as a ...
Dayar, Tugrul +3 more
core +2 more sources
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Microbial Cell Factories, 2018 Background Beyond pathway engineering, the metabolic state of the production host is critical in maintaining the efficiency of cellular production. The biotechnologically important yeast Saccharomyces cerevisiae adjusts its energy metabolism based on the
Maren Wehrs +7 more
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
On modeling approaches for the predictive simulation of living systms dymamics
Ontare, 2015 ONTARE. REVISTA DE INVESTIGACIÓN DE LA FACULTAD DE INGENIERÍA This research paper describes two main approaches that are currently available for modelling and simulating the evolution of dynamic living systems, namely the continuous-deterministic one,
Ivan Mura
doaj +1 more source
Abstract Interpretation for Probabilistic Termination of Biological Systems
, 2009 In a previous paper the authors applied the Abstract Interpretation approach for approximating the probabilistic semantics of biological systems, modeled specifically using the Chemical Ground Form calculus.
Francesca Levi +2 more
core +2 more sources
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
On the impact of hidden modeling assumptions on living systems- predictive dynamics
Ontare, 2015 ONTARE. REVISTA DE INVESTIGACIÓN DE LA FACULTAD DE INGENIERÍA This paper aims at showing the predictive modeling of living systems, particularly some commonly structured modeling assumptions which simplify the behavior of living systems.
Ivan Mura
doaj +1 more source