Results 81 to 90 of about 1,154,039 (314)

LONG-TERM RETENTION RATE OF CERTOLIZUMAB PEGOL IN PATIENTS WITH AXIAL SPONDYLOARTHRITIS: DATA FROM THE TURKBIO REGISTRY

Rheumatology Quarterly
Aim: Selecting the most effective treatment plan for a patient represents one of the most challenging issues in contemporary rheumatology. Clinicians must consider the long-term retention rate and the reasons for discontinuing candidate drugs.This study ...
Ahmet Karataş, Yavuz Pehlivan, Servet Akar, Soner Şenel, Aslıhan Avanoğlu Güler, Özgül Soysal Gündüz, Ayten Yazıcı, Sema Yılmaz, Rabia Pişkin Sağır, Nevsun İnanç, Gözde Yıldırım Çetin, Mehmet Pamir Atagündüz, Fatoş Önen   +12 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Tratamento da arterite de Takayasu Takayasu’s arteritis treatment

Revista Brasileira de Reumatologia, 2006
A arterite de Takayasu (AT) é uma vasculite granulomatosa crônica que envolve a aorta e seus principais ramos. A monitoração da atividade da doença e o melhor esquema terapêutico ainda têm sido um desafio para todos os que tratam estes pacientes ...
Alexandre Wagner Silva de Souza, Raissa Maria Sampaio Neves, Kathia Regina Oliveira, Emília Inoue Sato   +3 more
doaj   +1 more source

Developmental trends in targeted radionuclide therapy : Biological aspects

, 2008
Targeted radionuclide therapy of hematopoietic malignancies in the clinical setting has been achieved and similar successes with solid tumors and cells disseminated from them are likely within reach.
Carlsson, Jörgen,
core  

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Dynamics of body composition indicators in patients with early rheumatoid arthritis during therapy with methotrexate and biological drugs (pilot study)

Научно-практическая ревматология
Aim – to evaluate the parameters of body composition in patients with early rheumatoid arthritis on the background of anti-inflammatory therapy after 24 weeks of follow-up.Material and methods.
Yu. N. Gorbunova, L. V. Kondratyeva, T. V. Popkova, N. V. Demin, A. V. Smirnov, E. L. Nasonov   +5 more
doaj   +1 more source

The Danish National Registry for Biological Therapy in Inflammatory Bowel Disease

, 2016
Lone Larsen,1 Michael Dam Jensen,2 Michael Due Larsen,3 Rasmus Gaardskær Nielsen,4 Niels Thorsgaard,5 Ida Vind,6 Signe Wildt,7 Jens Kjeldsen8 1Department of Gastroenterology and Hepatology, Aalborg University Hospital, Aalborg,2Department of ...
Larsen MD, Wildt S, Kjeldsen J, Nielsen RG, Thorsgaard N, Jensen MD, Larsen L, Vind I   +7 more
core  

Gene therapy for inherited retinal and optic nerve degenerations

, 2017
Introduction: The eye is a target for investigational gene therapy due to the monogenic nature of many inherited retinal and optic nerve degenerations (IRD), its accessibility, tight blood-ocular barrier, the ability to non-invasively monitor for ...
Ciulla, Thomas A., Morral, Nuria, Nuria Morral, Thomas A. Ciulla, Bracha, Peter, Peter Bracha, Moore, Nicholas A., Nicholas A. Moore   +7 more
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Recommendations for the treatment of axial spondyloarthritis: An analysis of the updated ASAS/EULAR 2022 clinical guidelines

Научно-практическая ревматология
The article discusses the 2022 updated version of the collaborative ASAS/EULAR (Assessment in SpondyloArthritis international Society/European Alliance of Associations for Rheumatology) recommendations for the treatment of axial spondyloarthritis.
Sh. F. Erdes, T. V. Dubinina
doaj   +1 more source