Results 91 to 100 of about 1,154,039 (314)
Oral Effects of Biological Therapies
, 2017 This thesis describes the oral effects of biological agents which can be used to treat autoimmune conditions - having both a positive and negative effect on the periodontal and oral health.
Patel, Hemmali Rajesh
core
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Exploring the effectiveness of past-life therapy [PDF]
, 2000 Plan BThe concept of “Past-Life Therapy” (PLT) probably conjures up quizzical, or more likely, quite skeptical reactions in most people, particularly among professionals in the health care industry.
Christopher, Eric J.
core
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Biologic drugs induced vitiligo: case reports and review of literature
Frontiers in ImmunologyBiological drugs are extensively used to treat various inflammatory diseases, including psoriasis, atopic dermatitis (AD), and rheumatoid arthritis. While generally effective and safe, these therapies have been increasingly associated with secondary ...
Xinyi Shao +5 more
doaj +1 more source
BIOLOGICS IN DERMATOLOGIC THERAPY - AN UPDATE
Indian Journal of Dermatology, 2009 Biologics are protein molecules which are used in various diseases to target the specific points in the immunopathogenesis of the diseases. The molecules are produced by recombinant DNA technology. The molecules bind to the specific targets without interfering wtih rest of the pathogenetic pathways.
openaire +3 more sources
Biological therapy of pathological disorders [PDF]
, 2011 Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of Pharmacology and Toxicology Title of diploma thesis: Biological therapy of pathological disorders Author: Iva Libichová Supervisor: PharmDr. Marie Vopršálová, CSc.
Libichová, Iva
core
Biological Therapy and Risk of Malignancies: A Literature Review
, 2013 Data from literature show that the overall risk of cancer does not as a result from treatment with these drugs. The only cancer for which various authors have reported an increased risk, in some cases, are skin cancers, different from melanoma and ...
SANDRI, Gilda +2 more
core +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Biological strategies in rotator cuff repair: a clinical application and molecular background
EFORT Open ReviewsConventional repair of rotator cuff tears bears a variable but significant risk of incomplete healing. Biological therapies that accompany surgical rotator cuff repair include platelet-rich plasma, stem cells of different origins, and biological ...
Maciej Pawlak +2 more
doaj +1 more source