Results 101 to 110 of about 8,094,321 (309)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Application of Irreversible Thermodynamics to Biological Membrane Transport Phenomena

, 1973
An application of Onsager's Theory is made to biological transport phenomena. By transforming the coefficient matrix (the Onsager L matrix) to the diagonal form we obtain a new relation between the entropy production and the state parameters (flows or ...
Lau, Ying Tung
core  

Organization of two kinesins in a two-dimensional microtubule network.

PLoS ONE
In intracellular active transport, molecular motors are responsible for moving biological cargo along networks of microtubules that serve as scaffolds. Cargo dynamics can be modified by different features of microtubule networks such as geometry, density,
Jesús M Bergues, Fernando Falo
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source

The road less travelled

, 2015
Fewer Australian children walking or cycling to school today than ever before, according to this report. ACTIVE TRANSPORT – WHAT? HOW? AND WHY? When moving from place to place, people can get to where they are going using either passive transport (e.g.
Active Healthy Kids Australia
core  

Oscillatory active Brownian motion: a minimal model for sperm dynamics

New Journal of Physics
Active biological microswimmers typically combine persistent self-propulsion with cyclic motion generated by flagellar or ciliary beating. However, standard active Brownian motion (ABM) does not explicitly account for these intrinsic oscillations.
Adrian Pacheco-Pozo, Arturo Matamoros Volante, Pilar Ameijeiras, Mariano G Buffone, Diego Krapf   +4 more
doaj   +1 more source

Bioinks in systems biology: integrating biomaterial design with cellular network modelling for predictive biofabrication

Frontiers in Bioengineering and Biotechnology
Bioinks facilitate patient-relevant tissue models by merging living cells with a programmable matrix whose composition, mechanics, and transport properties can be altered in three dimensions and tracked over time.
Inamul Hasan Madar, Jayant Pawar, Punitha Muruganantham, Syed Suhaib Ahmed, Vansh Vohra, Janakiraman Velayudam   +5 more
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source