Results 31 to 40 of about 403,971 (148)
In vitro transport of methotrexate by Drosophila Multidrug Resistance-associated Protein. [PDF]
PLoS ONE, 2018 Methotrexate (MTX) is a widely used chemotherapeutic agent, immune suppressant and antimalarial drug. It is a substrate of several human ABC proteins that confer multidrug resistance to cancer cells and determine compartmentalization of a wide range of ...
Agnes Karasik +2 more
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Guanine-based amphiphiles: synthesis, ion transport properties and biological activity
Bioorganic & Medicinal Chemistry, 2015 Novel amphiphilic guanine derivatives, here named Gua1 and Gua2, have been prepared through few, simple and efficient synthetic steps. In ion transport experiments through phospholipid bilayers, carried out to evaluate their ability to mediate H(+) transport, Gua2 showed high activity.
MUSUMECI, DOMENICA +5 more
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Overcrowding induces fast colloidal solitons in a slowly rotating potential landscape
Nature Communications, 2023 Collective particle transport across periodic energy landscapes is ubiquitously present in many condensed matter systems spanning from vortices in high-temperature superconductors, frictional atomic sliding, driven skyrmions to biological and active ...
Eric Cereceda-López +4 more
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RSC Advances, 2021 A series of squaramido-tethered bisbenzimidazoles were synthesized and found to exhibit moderate anion transport and cytotoxicity.
Zhong-Kun Wang +4 more
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Membranes, 2022 Proteins transporting ions or other molecules across the membrane, whose proper concentration is required to maintain homeostasis, perform very sophisticated biological functions.
Irena Roterman +2 more
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206 An artificial active DNA transporter from biological building blocks [PDF]
Journal of Biomolecular Structure and Dynamics, 2013 The selective transport of molecules across membrane pores is an essential biological process that occurs in all living organisms. Examples include the chaperone of proteins and mRNA in and out the cell nucleus mediated by the nuclear pore complex and the transport of specific molecules across a biological membrane mediated by active and passive ...
Lorenzo Franceschini +2 more
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Physical Review Research, 2021 Evidence suggests that the transport rate of a passive particle at long time scales is enhanced due to interactions with the surrounding active ones in a size- and composition-dependent manner.
Efe Ilker +2 more
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InstrumentsMaintaining physiologically controlled conditions during the transport of biological experiments remains a long-standing but under-addressed challenge in spaceflight operations. Pre-launch thermal or mechanical stress induce artefacts that compromise the
Sebastian Feles +2 more
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Evolutionary ancestry and novel functions of the mammalian glucose transporter (GLUT) family
BMC Evolutionary Biology, 2010 Background In general, sugar porters function by proton-coupled symport or facilitative transport modes. Symporters, coupled to electrochemical energy, transport nutrients against a substrate gradient.
Patron Nicola +2 more
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Learning to control active matter
Physical Review Research, 2021 The study of active matter has revealed novel non-equilibrium collective behaviors, illustrating their potential as a new materials platform. However, most work treat active matter as unregulated systems with uniform microscopic energy input, which we ...
Martin J. Falk +3 more
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