Results 41 to 50 of about 403,971 (148)

Methodological advances in imaging intravital axonal transport [version 1; referees: 3 approved]

F1000Research, 2017
Axonal transport is the active process whereby neurons transport cargoes such as organelles and proteins anterogradely from the cell body to the axon terminal and retrogradely in the opposite direction.
James N. Sleigh, Alessio Vagnoni, Alison E. Twelvetrees, Giampietro Schiavo   +3 more
doaj   +1 more source

Synthesis and Biological Evaluation of Dihydromotuporamine Derivatives in Cells Containing Active Polyamine Transporters [PDF]

Journal of Medicinal Chemistry, 2005
Dihydromotuporamine C (4) and its 4,4-triamine analogue (5) were synthesized in good yield using ring-closing metathesis (RCM) methods. Comparison of their biological activities (Ki determinations in L1210 cells and IC50 determinations in L1210, CHO, and CHO-MG cells) revealed that the motuporamine derivatives do not use the polyamine transporter (PAT)
Navneet, Kaur, Jean-Guy, Delcros, Bénédicte, Martin, Otto, Phanstiel   +3 more
openaire   +3 more sources

Hydrodynamic Fluidic Pump Empowered Sensitive Recognition and Active Transport of Hydrogen Peroxide in 1D Channels

Advanced Science
Through synthetic chemistry, the development of molecular devices for the precise selective recognition and active transport of small molecules stands as one of the most ambitious objectives in extensive medical, environmental, and biological ...
Shuya Liu, Yongxian Guo, Yanjun Gong, Yanze Wei, Qiongzheng Hu, Li Yu   +5 more
doaj   +1 more source

Two-Species Active Transport along Cylindrical Biofilaments is Limited by Emergent Topological Hindrance

Physical Review X, 2018
Active motion of molecules along filamentous structures is a crucial feature of cell biology and is often modeled with the paradigmatic asymmetric simple exclusion process.
Patrick Wilke, Emanuel Reithmann, Erwin Frey   +2 more
doaj   +1 more source

Hydrodynamics of a Granular Gas in a Heterogeneous Environment

Entropy, 2017
We analyze the transport properties of a low density ensemble of identical macroscopic particles immersed in an active fluid. The particles are modeled as inelastic hard spheres (granular gas).
Francisco Vega Reyes, Antonio Lasanta
doaj   +1 more source

Hijacking Endocytosis and Autophagy in Extracellular Vesicle Communication: Where the Inside Meets the Outside

Frontiers in Cell and Developmental Biology, 2021
Extracellular vesicles, phospholipid bilayer-membrane vesicles of cellular origin, are emerging as nanocarriers of biological information between cells. Extracellular vesicles transport virtually all biologically active macromolecules (e.g., nucleotides,
Giona Pedrioli, Giona Pedrioli, Paolo Paganetti, Paolo Paganetti   +3 more
doaj   +1 more source

Biological and Medical Aspects of Active Heal Transport of Bile Acids

Annals of Medicine, 1991
The active transport of conjugated bile acids by the ileum is responsible for the enterohepatic circulation of bile acids, a physiological process that ensures an ample supply to the intestine of these key biological surfactants, irrespective of the rate of their biosynthesis from cholesterol.
A F, Hofmann, C D, Schteingart, J, Lillienau   +2 more
openaire   +2 more sources

Taming membranes: functional immobilization of biological membranes in hydrogels. [PDF]

PLoS ONE, 2011
Single molecule studies on membrane proteins embedded in their native environment are hampered by the intrinsic difficulty of immobilizing elastic and sensitive biological membranes without interfering with protein activity.
Ilja Kusters, Nobina Mukherjee, Menno R de Jong, Sander Tans, Armağan Koçer, Arnold J M Driessen   +5 more
doaj   +1 more source

Biological activity of synthetic ionophores: ion transporters as prospective drugs?

Chemical Science, 2013
The control of ion transport and homeostasis is a critical function of living organisms. In this perspective, an overview of different synthetic systems capable of facilitating the transmembrane transport of ions along with the biological activity exerted by these compounds is presented.
Ignacio Alfonso, Roberto Quesada
openaire   +1 more source

Transport in cellular aggregates described by fluctuating hydrodynamics

Physical Review Research
Biological functionality of cellular aggregates is largely influenced by the activity and displacements of individual constituent cells. From a theoretical perspective this activity can be characterized by hydrodynamic transport coefficients of ...
Subhadip Chakraborti, Vasily Zaburdaev
doaj   +1 more source