Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Self‐Assembled Supramolecular Materials for Substrate Transport by External Stimuli
Macromolecular Materials and EngineeringSubstrate transport within biological tissues is diverse, with the most fundamental process being transport across cell membranes, which plays a crucial role in sustaining life.
Xue Li +3 more
doaj +1 more source
Confined gas transport in low-dimensional materials
International Journal of Smart and Nano MaterialsGas transport under confinement exhibits a plethora of physical and chemical phenomena that differ from those observed in bulk media, owing to the deviations of continuum description at the molecular level.
Hongwei Duan +4 more
doaj +1 more source
Effect of a 2-HP-β-Cyclodextrin Formulation on the Biological Transport and Delivery of Chemotherapeutic PLGA Nanoparticles. [PDF]
Drug Des Devel Ther, 2021 Zheng K +10 more
europepmc +1 more source
How the asymmetry of internal potential influences the shape of I-V characteristic of nanochannels
, 2006 Ion transport in biological and synthetic nanochannels is characterized by such phenomena as ion current fluctuations, rectification, and pumping. Recently, it has been shown that the nanofabricated synthetic pores could be considered as analogous to ...
Cole K. +9 more
core +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Ecological aspects of using biological diesel oil in railway transport [PDF]
Transport, 2008 The number of various transport facilities used in Europe is rapidly growing. They release a big amount of pollutants into the atmosphere. Therefore, environment protection from these pollutants ejected by internal combustion engines is a key problem ...
L. P. Lingaitis, S. Pukalskas
doaj +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Savremena saznanja o molekulskim mehanizmima regulacije homeostaze gvožđa [PDF]
Vojnosanitetski Pregled, 2002 Popović Petar +2 more
doaj +1 more source