Results 71 to 80 of about 1,765,133 (301)
A method for molecular dynamics on curved surfaces [PDF]
, 2016 Dynamics simulations of constrained particles can greatly aid in understanding the temporal and spatial evolution of biological processes such as lateral transport along membranes and self-assembly of viruses.
Kusters, Remy, Paquay, Stefan
core +2 more sources
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Frontiers in ChemistryCalcium carbonate (CaCO3) is an incredibly abundant mineral on Earth, with over 90% of it being found in the lithosphere. To address the CO2 crisis and combat ocean acidification, it is essential to produce more CaCO3 using various synthetic methods ...
Jackson Comes +4 more
doaj +1 more source
An Energetic Variational Approach for ion transport
, 2014 The transport and distribution of charged particles are crucial in the study of many physical and biological problems. In this paper, we employ an Energy Variational Approach to derive the coupled Poisson-Nernst-Planck-Navier-Stokes system.
Liu, Chun, Sheng, Ping, Xu, Shixin
core +2 more sources
Weak ergodicity breaking of receptor motion in living cells stemming from random diffusivity [PDF]
, 2015 Molecular transport in living systems regulates numerous processes underlying biological function. Although many cellular components exhibit anomalous diffusion, only recently has the subdiffusive motion been associated with nonergodic behavior.
Lapeyre Jr., Gerald J. +5 more
core +4 more sources
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Nanomaterials Designed for Antiviral Drug Delivery Transport across Biological Barriers
Pharmaceutics, 2020 Viral infections are a major global health problem, representing a significant cause of mortality with an unfavorable continuously amplified socio-economic impact.
Florina-Daniela Cojocaru +9 more
doaj +1 more source
A thermodynamic paradigm for solution demixing inspired by nuclear transport in living cells
, 2017 Living cells display a remarkable capacity to compartmentalize their functional biochemistry. A particularly fascinating example is the cell nucleus. Exchange of macromolecules between the nucleus and the surrounding cytoplasm does not involve traversing
Elbaum, Michael +2 more
core +1 more source
Thermal Migration in Biological Transport?
Biophysical Journal, 1965 It is shown by thermodynamic arguments and by semiquantitative considerations that the contribution of thermal migration to biological transport is likely to be small.
openaire +2 more sources