Results 61 to 70 of about 5,433,801 (311)

Thermal Migration in Biological Transport?

open access: yesBiophysical Journal, 1965
It is shown by thermodynamic arguments and by semiquantitative considerations that the contribution of thermal migration to biological transport is likely to be small.
openaire   +2 more sources

A multiscale description of growth and transport in biological tissues [PDF]

open access: yesTheoretical and Applied Mechanics, 2007
We study a growing biological tissue as an open biphasic mixture with mass exchange between phases. The solid phase is identified with the matrix of a porous medium, while the fluid phase is comprised of water, together with all the dissolved chemical ...
Grillo A.   +5 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Biological solutions to transport network design [PDF]

open access: yesProceedings of the Royal Society B: Biological Sciences, 2007
Transport networks are vital components of multicellular organisms, distributing nutrients and removing waste products. Animal and plant transport systems are branching trees whose architecture is linked to universal scaling laws in these organisms.
Bebber, D   +4 more
openaire   +2 more sources

Improvements in the utilization of calcium carbonate in promoting sustainability and environmental health

open access: yesFrontiers in Chemistry
Calcium carbonate (CaCO3) is an incredibly abundant mineral on Earth, with over 90% of it being found in the lithosphere. To address the CO2 crisis and combat ocean acidification, it is essential to produce more CaCO3 using various synthetic methods ...
Jackson Comes   +4 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Phylogeny and chemistry of biological mineral transport

open access: yesBone, 2020
Three physiologically mineralizing tissues - teeth, cartilage and bone - have critical common elements and important evolutionary relationships. Phylogenetically the most ancient densely mineralized tissue is teeth. In jawless fishes without skeletons, tooth formation included epithelial transport of phosphates, a process echoed later in bone ...
Paul H, Schlesinger   +7 more
openaire   +3 more sources

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