Results 121 to 130 of about 27,882,966 (366)

Biological basis and treatment of frailty and sarcopenia.

Cardiovascular Research
In an ageing society, the importance of maintaining healthy life expectancy has been emphasized. As a result of age-related decline in functional reserve, frailty is a state of increased vulnerability and susceptibility to adverse health outcomes with a ...
Ryosuke Sato, M. Vatic, Guilherme Wesley Peixoto da Fonseca, Stefan D. Anker, S. von Haehling   +4 more
semanticscholar   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Annual Report - Marine Biological Laboratory, 2002

, 2003
Annual report of the Marine Biological Laboratory in Woods Hole. 2002.
Marine Biological Laboratory (Woods Hole MA)
core  

NUP37 promotes the proliferation and invasion of glioma cells through DNMT1-mediated methylation

Cell Death Discovery
Nuclear regulation has potential in cancer therapy, with the nuclear pore complex (NPC) serving as a critical channel between the nucleus and cytoplasm, playing a role in regulating various biological processes and cancer.
Yongqiang Lv, Chaolian Wang, Ruoyu Liu, Shaoxian Wu, Junjun Chen, Xiao Zheng, Tianwei Jiang, Lujun Chen   +7 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Annual Report - Marine Biological Laboratory, 1950

, 1951
Annual report of the Marine Biological Laboratory in Woods Hole. 1950.
Marine Biological Laboratory (Woods Hole MA)
core  

Physico-Chemical and Biological Treatment of Olive Mill Wastewater by Rotating Biological Contactor (RBC) Reactors [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 2006
The removal performance of total poly phenols and orthodiphenols (o-diphenols) content in olive mill waste (OMW) was investigated with a three stages cross flow laboratory scale rotating biological contactor (RBC) in the present study.
Iran Alemzadeh, Alireza Nazemi
doaj  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Annual Report - Marine Biological Laboratory, 1941

, 1942
Annual report of the Marine Biological Laboratory in Woods Hole. 1941.
Marine Biological Laboratory (Woods Hole MA)
core  

Cx43 hemichannel-mediated paracrine involves in the promotion of MSCs on skin wound healing

Stem Cell Research & Therapy
Background Mesenchymal stem cells (MSCs) exhibit therapeutic potential in wound healing, primarily through their paracrine effects. However, the specific mechanisms underlying these effects remain ambiguous.
Xiangya Dou, Yaping Zhang, Xuezhou Yang, Yinbo Niu, Dong-En Wang, Huiyun Xu   +5 more
doaj   +1 more source