Results 231 to 240 of about 19,142,092 (295)

Detection of schistosome cercariae in water: A systematic review of traps and attractants. [PDF]

PLoS Negl Trop Dis
Rupp A, Templeton MR, Sioné L, Pitol-Garcia A, Braun L.   +4 more
europepmc   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Statistical methods to evaluate discrete Boolean mathematical models from systems biology experimental data sets

IFAC-PapersOnLine
Antonio Bensussen, J. Arturo Arciniega-González, Rosario Pacheco-Marín, Elena R. Álvarez-Buylla, Juan Carlos Martínez-García   +4 more
openaire   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Quantitative logics for directed evolution of an asexual population. [PDF]

PLoS One
Park K.
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

PumpKin: A machine-learning pipeline for automatically tracking localized kinematics in freely moving C. elegans. [PDF]

PLoS Comput Biol
Shappell E, Buggs D, Walcott J, Lu H.
europepmc   +1 more source

Identifying DNA mutations in Sepia, White, Yellow, and Vestigial genes in D. melanogaster - Integrating inquiry-based experiential learning into undergraduate Genetics Laboratory curriculum. [PDF]

PLoS One
Rentachintala KK, Bricker CAK, Jain PR, Nanjundan M.   +3 more
europepmc   +1 more source