Results 61 to 70 of about 5,448,839 (367)
Approximate parameter inference in systems biology using gradient matching: a comparative evaluation [PDF]
, 2016 Background: A challenging problem in current systems biology is that of parameter inference in biological pathways expressed as coupled ordinary differential equations (ODEs).
Filippone, Maurizio +4 more
core +1 more source
iScience, 2022 Summary: In vivo quantitative assessment of structural and functional biomarkers is essential for characterizing the pathophysiology of congenital disorders.
Tanveer Teranikar +9 more
doaj
, 2012 Increasingly complex applications involve large datasets in combination with non-linear and high dimensional mathematical models. In this context, statistical inference is a challenging issue that calls for pragmatic approaches that take advantage of ...
Box GEP +4 more
core +1 more source
Robust, automated sleep scoring by a compact neural network with distributional shift correction. [PDF]
, 2019 Studying the biology of sleep requires the accurate assessment of the state of experimental subjects, and manual analysis of relevant data is a major bottleneck.
Barger, Zeke +4 more
core +1 more source
Multiplexed protein profiling reveals spatial subcellular signaling networks
iScience, 2022 Summary: Protein-protein interaction networks are altered in multi-gene dysregulations in many disorders. Image-based protein multiplexing sheds light on signaling pathways to dissect cell-to-cell heterogeneity, previously masked by the bulk assays ...
Shuangyi Cai +7 more
doaj
Experimental design for parameter estimation of gene regulatory networks. [PDF]
PLoS ONE, 2012 Systems biology aims for building quantitative models to address unresolved issues in molecular biology. In order to describe the behavior of biological cells adequately, gene regulatory networks (GRNs) are intensively investigated.
Bernhard Steiert +3 more
doaj +1 more source
Bonds and Bytes: the Odyssey of Structural Biology [PDF]
arXiv, 2023 Characterizing structural and dynamic properties of proteins and large macromolecular assemblies is crucial to understand the molecular mechanisms underlying biological functions. In the field of Structural Biology, no single method comprehensively reveals the behavior of biological systems across various spatio-temporal scales.
arxiv
Estimation methods for heterogeneous cell population models in systems biology
Journal of the Royal Society Interface, 2018 Heterogeneity among individual cells is a characteristic and relevant feature of living systems. A range of experimental techniques to investigate this heterogeneity is available, and multiple modelling frameworks have been developed to describe and ...
S. Waldherr
semanticscholar +1 more source
Empowering statistical methods for cellular and molecular biologists. [PDF]
, 2019 We provide guidelines for using statistical methods to analyze the types of experiments reported in cellular and molecular biology journals such as Molecular Biology of the Cell.
Pollard, Daniel A +2 more
core
Evaluating the origin and spread of spotted lanternfly (Lycorma delicatula) in Japan
Population Ecology, Volume 67, Issue 2, Page 162-179, April 2025.The invasive spotted lanternfly (Lycorma delicatula) is native to China and is a serious economic pest in the Republic of Korea and the United States, though it is not considered a pest in Japan. We established a distribution map of L. delicatula in Japan through a comprehensive review of published literature and citizen science reports and analyzed ...
Matthew T. Kamiyama +5 more
wiley +1 more source