Results 61 to 70 of about 2,458,031 (313)

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Robust model-based analysis of single-particle tracking experiments with Spot-On. [PDF]

open access: yes, 2018
Single-particle tracking (SPT) has become an important method to bridge biochemistry and cell biology since it allows direct observation of protein binding and diffusion dynamics in live cells.
Darzacq, Xavier   +5 more
core   +2 more sources

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

NEW SILK: Studying experimental touchpoints between material science, synthetic biology, design and art

open access: yesTemes de Disseny, 2018
This article presents a study in which new materials are developed through experimental knowledge construction and knowledge exchange between different disciplines. The New Silk research project (2017-2020) is the building block for the research.
Kirsi Niinimäki   +2 more
doaj   +3 more sources

Relationship between the Working Methods and Lower Secondary School Students’ Performance and Attitudes towards Biology

open access: yesLUMAT, 2013
The contribution of different working methods and learning environments to grade nine students’ performance in biology as well as their attitudes towards biology as school subject were studied.
Anna Uitto   +2 more
doaj   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

Designing and Implementation of the Blended Instructional Model Based on Reigeluth, Merrill, Keller and the Investigation of Its Effect on Students’ Learning in Biology Course [PDF]

open access: yesInterdisciplinary Journal of Virtual Learning in Medical Sciences, 2015
Introduction Instruction and learning play an important role in the twenty-first century which has been named the knowledge society and knowledge economy.
Mohammad Shahalizadeh   +2 more
doaj   +1 more source

Improving empirical competence for students in high school in Vietnam

open access: yesTạp chí Khoa học, 2023
Improving experimental competence for students is an essential mission in general education nowadays, helping students initially establish scientific research capacity and is a part of cognitive capacity of scientific knowledge, especially in the study ...
PHAM Thi Huong, PHAM Nhu Quynh
doaj   +1 more source

Proceedings of the COST SUSVAR/ECO-PB Workshop on organic plant breeding strategies and the use of molecular markers [PDF]

open access: yes, 2005
In many countries,national projects are in progress to investigate the sustainable low-input approach.In the present COST network,these projects are coordinated by means of exchange of materials,establishing common methods for assessment and statistical ...

core  

ProbCD: enrichment analysis accounting for categorization uncertainty [PDF]

open access: yes, 2007
As in many other areas of science, systems biology makes extensive use of statistical association and significance estimates in contingency tables, a type of categorical data analysis known in this field as enrichment (also over-representation or ...
A Lewin   +22 more
core   +5 more sources

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