Results 51 to 60 of about 19,142,092 (295)

Typology and specificity of biology philosophical problems

Семиотические исследования, 2023
The article examines a new complexity problem of ontology brought to life by technical interventions in living systems. The object is the philosophical problems of biology, the subject of the research is to identify the specifics and typology of the ...
Valentina E. Rednikina, Natalya А. Yastreb   +1 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Molecular Biology

, 2023
This course covers a detailed analysis of the biochemical mechanisms that control the maintenance, expression, and evolution of prokaryotic and eukaryotic genomes. The topics covered in lectures and readings of relevant literature include gene regulation,
Faculty, Biology Department
core  

Relationship between the Working Methods and Lower Secondary School Students’ Performance and Attitudes towards Biology

LUMAT, 2013
The contribution of different working methods and learning environments to grade nine students’ performance in biology as well as their attitudes towards biology as school subject were studied.
Anna Uitto, Pirkko Kärnä, Riikka Hakonen   +2 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

EXPERIMENTAL METHODS

, 2022
Experimental Methods, Scaling Laws, DIC (Digital Image Correlation), Hydrodynamic of Flexible Structures, Wave-in-deck, Hybride model testing, Vibrations, Fatigue testing, Large scale impact testing, Corrosion testing, Full-scale iced load measurements,
Murayama, H., Michailidis, C., Kaeding, Patrick, Ehlers, Sören, Abdussamie, N., Fu, S., Kolari, K., Hoogeland, M., Seo, J.K., Branner, K., Lara, P., Rizzo, C.M.   +11 more
core  

Functional Genomics, Proteomics, Metabolomics and Bioinformatics for Systems Biology [PDF]

, 2013
peer reviewedThis chapter introduces systems biology, its context, aims, concepts and strategies. It then describes approaches and methods used for collection of high-dimensional structural and functional genomics data, including epigenomics ...
Nitin Baliga, Reinhard Schneider, KOLODKIN, Alexey, Nikos Vlassis, Ballereau, S., SCHNEIDER, Reinhard, VLASSIS, Nikos, GLAAB, Enrico, Hassan Ahmed, Charles Auffray, Amphun Chaiboonchoe, Johann Pellet, Leroy Hood, Enrico Glaab, HOOD, Leroy, BIRYUKOV, Maria, Stéphane Ballereau, Ahmed, H., BALLING, Rudi, Rudi Balling, Baliga, N., Alexei Kolodkin, Auffray, C., Chaiboonchoe, A., Pellet, J., Maria Biryukov   +25 more
core   +1 more source

NEW SILK: Studying experimental touchpoints between material science, synthetic biology, design and art

Temes de Disseny, 2018
This article presents a study in which new materials are developed through experimental knowledge construction and knowledge exchange between different disciplines. The New Silk research project (2017-2020) is the building block for the research.
Kirsi Niinimäki, Camilla Groth, Pirjo Kääriäinen   +2 more
doaj   +3 more sources

Mitigation of aging-related plasticity decline through taurine supplementation and environmental enrichment

Scientific Reports
Aging-related biochemical changes in nerve cells lead to dysfunctional synapses and disrupted neuronal circuits, ultimately affecting vital processes such as brain plasticity, learning, and memory.
Aleksandra Gawryluk, Anita Cybulska-Klosowicz, Agata Charzynska, Renata Zakrzewska, Alicja Sobolewska, Malgorzata Kossut, Monika Liguz-Lecznar   +6 more
doaj   +1 more source