Results 31 to 40 of about 1,186,089 (258)

PCR-based profiling of transcription factor activity in vivo by a virus-based reporter battery

iScience, 2022
Summary: Understanding the molecular mechanisms of gene regulation is pivotal for understanding how cells establish and modify their identities and functions.
Hitomi Abe, Kentaro Abe
doaj   +1 more source

Specificity and efficiency of tamoxifen-mediated Cre induction is equivalent regardless of age

iScience, 2023
Summary: Temporally controlling Cre recombination through tamoxifen (Tam) induction has many advantages for biomedical research. Most studies report early post-natal/juvenile (12 m.o.).
Collyn M. Kellogg, Kevin Pham, Sunghwan Ko, Jillian E.J. Cox, Adeline H. Machalinski, Michael B. Stout, Amanda L. Sharpe, Michael J. Beckstead, Ana J. Chucair-Elliott, Sarah R. Ocañas, Willard M. Freeman   +10 more
doaj   +1 more source

A NEW METHOD FOR THE GENERATION AND USE OF FOCUSED ULTRASOUND IN EXPERIMENTAL BIOLOGY [PDF]

Journal of General Physiology, 1942
1. An efficient generator of focused ultrasound has been designed, built, and successfully operated. 2. The generator has been used to produce focal heating in the centers of paraffin blocks, and in a similar manner, focal areas of destruction were obtained deep in fresh liver tissue with minimal effects at the surface and no effects on ...
J G, Lynn, R L, Zwemer, A J, Chick, A E, Miller   +3 more
openaire   +2 more sources

Fabrication of a new all-in-one microfluidic dielectrophoresis integrated chip and living cell separation

iScience, 2022
Summary: Microfluidic dielectrophoresis (DEP) technology has been applied to many devices to perform label-free target cell separation. Cells separated by these devices are used in laboratories, mainly for medical research.
Kyoichi Oshiro, Yoshikazu Wakizaka, Masayo Takano, Takayuki Itoi, Hiroki Ohge, Kazumi Koba, Kyoko Yarimizu, So Fujiyoshi, Fumito Maruyama   +8 more
doaj   +1 more source

Computer-Animation on NCE Students’ Academic Performance in Vertebrate Anatomy and Physiology in Colleges of Education

Indonesian Journal of Educational Research and Review, 2022
The low ability of students causes students to have difficulty understanding some Biology concepts. In addition, the time given for biology practicum is still limited.
N. A. Ala, A. M. Ishyaku, S. B. Adamu, A. O. Onojah   +3 more
doaj   +1 more source

InVision: An optimized tissue clearing approach for three-dimensional imaging and analysis of intact rodent eyes

iScience, 2021
Summary: The mouse eye is used to model central nervous system development, pathology, angiogenesis, tumorigenesis, and regenerative therapies. To facilitate the analysis of these processes, we developed an optimized tissue clearing and depigmentation ...
Akshay Gurdita, Philip E.B. Nickerson, Neno T. Pokrajac, Arturo Ortín-Martínez, En Leh Samuel Tsai, Lacrimioara Comanita, Nicole E. Yan, Parnian Dolati, Nobuhiko Tachibana, Zhongda C. Liu, Joel D. Pearson, Danian Chen, Rod Bremner, Valerie A. Wallace   +13 more
doaj   +1 more source

Research-driven education: An introductory course to systems and synthetic biology

Frontiers in Systems Biology, 2022
Systems and Synthetic Biology are complementary fields emerging side-by-side into mainstream scientific research. Whilst systems biologists focus on understanding natural systems, synthetic biologists wish to modify, adapt and re-purpose biological ...
Robert W. Smith, Luis Garcia-Morales, Luis Garcia-Morales, Vitor A. P. Martins dos Santos, Vitor A. P. Martins dos Santos, Edoardo Saccenti   +5 more
doaj   +1 more source

Data Management and Modeling in Plant Biology

Frontiers in Plant Science, 2021
The study of plant-environment interactions is a multidisciplinary research field. With the emergence of quantitative large-scale and high-throughput techniques, amount and dimensionality of experimental data have strongly increased.
Maria Krantz, David Zimmer, Stephan O. Adler, Anastasia Kitashova, Edda Klipp, Timo Mühlhaus, Thomas Nägele   +6 more
doaj   +1 more source

Reproducible chemostat cultures to minimize eukaryotic viruses from fecal transplant material

iScience
Summary: Recent studies indicate an important role of bacteriophages for successful fecal microbiota transplantation (FMT). However, wider clinical applications of FMT are hampered by to donor variability and concerns of infection risks by bacteria and ...
Signe Adamberg, Torben Sølbeck Rasmussen, Sabina Brigitte Larsen, Xiaotian Mao, Dennis Sandris Nielsen, Kaarel Adamberg   +5 more
doaj   +1 more source

Multiplexed CRISPR gene editing in primary human islet cells with Cas9 ribonucleoprotein

iScience
Summary: Successful genome editing in primary human islets could reveal features of the genetic regulatory landscape underlying β cell function and diabetes risk.
Romina J. Bevacqua, Weichen Zhao, Emilio Merheb, Seung Hyun Kim, Alexander Marson, Anna L. Gloyn, Seung K. Kim   +6 more
doaj   +1 more source