Results 31 to 40 of about 19,142,092 (295)

Two Years Later: Journals Are Not Yet Enforcing the ARRIVE Guidelines on Reporting Standards for Pre-Clinical Animal Studies [PDF]

, 2014
There is growing concern that poor experimental design and lack of transparent reporting contribute to the frequent failure of pre-clinical animal studies to translate into treatments for human disease.
Sandra Amor (506326), Lidster, K., Baker, David, Amor, Sandra, Sottomayor, A, Baker David, Sottomayor, Ana, Amor, S., David Baker (11642), Sottomayor, A., Lidster, Katie, Ana Sottomayor, Lidster Katie, Baker, D., Baker, D, Lidster, K, Amor, S, Amor Sandra, Katie Lidster, Sandra Amor, Katie Lidster (479714), David Baker, Sottomayor Ana, Ana Sottomayor (506325)   +23 more
core   +1 more source

Research-driven education: An introductory course to systems and synthetic biology

Frontiers in Systems Biology, 2022
Systems and Synthetic Biology are complementary fields emerging side-by-side into mainstream scientific research. Whilst systems biologists focus on understanding natural systems, synthetic biologists wish to modify, adapt and re-purpose biological ...
Robert W. Smith, Luis Garcia-Morales, Luis Garcia-Morales, Vitor A. P. Martins dos Santos, Vitor A. P. Martins dos Santos, Edoardo Saccenti   +5 more
doaj   +1 more source

Philosophical issues in experimental biology [PDF]

, 2006
Introduction: Traditionally, studies in the philosophy of biology have been strongly centered on evolutionary biology and systematics. To be sure, during the last four decades the field of molecular biology has been subject to substantial philosophical ...
Brigandt, Ingo
core   +1 more source

Data Management and Modeling in Plant Biology

Frontiers in Plant Science, 2021
The study of plant-environment interactions is a multidisciplinary research field. With the emergence of quantitative large-scale and high-throughput techniques, amount and dimensionality of experimental data have strongly increased.
Maria Krantz, David Zimmer, Stephan O. Adler, Anastasia Kitashova, Edda Klipp, Timo Mühlhaus, Thomas Nägele   +6 more
doaj   +1 more source

Biological invasions in agricultural settings: insights from evolutionary biology and population genetics [PDF]

, 2011
Invasion biology and agriculture are intimately related for several reasons and in particular because many agricultural pest species are recent invaders. In this article we suggest that the reconstruction of invasion routes with population genetics-based
Thomas Guillemaud, Ciosi, Marc, Lombaert, Eric, Ciosi, M., Éric Lombaert, Estoup, Arnaud, Guillemaud, T., Estoup, A., Guillemaud, Thomas, Marc Ciosi, Arnaud Estoup, Guillemaud, Thomas,, Lombaert, E.   +12 more
core   +1 more source

Reproducible chemostat cultures to minimize eukaryotic viruses from fecal transplant material

iScience
Summary: Recent studies indicate an important role of bacteriophages for successful fecal microbiota transplantation (FMT). However, wider clinical applications of FMT are hampered by to donor variability and concerns of infection risks by bacteria and ...
Signe Adamberg, Torben Sølbeck Rasmussen, Sabina Brigitte Larsen, Xiaotian Mao, Dennis Sandris Nielsen, Kaarel Adamberg   +5 more
doaj   +1 more source

Multiplexed CRISPR gene editing in primary human islet cells with Cas9 ribonucleoprotein

iScience
Summary: Successful genome editing in primary human islets could reveal features of the genetic regulatory landscape underlying β cell function and diabetes risk.
Romina J. Bevacqua, Weichen Zhao, Emilio Merheb, Seung Hyun Kim, Alexander Marson, Anna L. Gloyn, Seung K. Kim   +6 more
doaj   +1 more source

Through the looking glass : attempting to predict future opportunities and challenges in experimental biology

, 2023
To celebrate its centenary year, Journal of Experimental Biology (JEB) commissioned a collection of articles examining the past, present and future of experimental biology.
Franklin, Craig E.,, Patek, Sheila N., McHenry, Matthew J., Wright, Patricia A.,, Schulte, Patricia M.,, Patek, Sheila N.,, Gilmour, Kathleen M., McHenry, Matthew J.,, Terblanche, John S., Sane, Sanjay P., Wright, Patricia A., Daley, Monica A., Gilmour, Kathleen M.,, Terblanche, John S.,, Egginton, Stuart, Kelber, Almut,, Sane, Sanjay P.,, Schulte, Patricia M., Daley, Monica A.,, Kelber, Almut, Egginton, Stuart,, Franklin, Craig E., Lund University.   +22 more
core   +1 more source

Present Impact of AlphaFold2 Revolution on Structural Biology, and an Illustration With the Structure Prediction of the Bacteriophage J-1 Host Adhesion Device

Frontiers in Molecular Biosciences, 2022
In 2021, the release of AlphaFold2 - the DeepMind’s machine-learning protein structure prediction program - revolutionized structural biology. Results of the CASP14 contest were an immense surprise as AlphaFold2 successfully predicted 3D structures of ...
Adeline Goulet, Christian Cambillau, Christian Cambillau   +2 more
doaj   +1 more source

Myosin VI depletion delays neuromuscular junction maturation and exacerbates muscle performance

Scientific Reports
Unconventional myosin VI (MVI) is an ATP-dependent actin-binding molecular motor that participates in numerous cellular and tissue functions, including striated muscle physiology.
Jolanta Nowak, Paloma Alvarez-Suarez, Tomasz Włodarczyk, Renata Zakrzewska, Paweł Marek Boguszewski, Maria Jolanta Rędowicz, Marta Gawor   +6 more
doaj   +1 more source