Robust, automated sleep scoring by a compact neural network with distributional shift correction. [PDF]
, 2019 Studying the biology of sleep requires the accurate assessment of the state of experimental subjects, and manual analysis of relevant data is a major bottleneck.
Barger, Zeke +4 more
core +1 more source
Research-driven education: An introductory course to systems and synthetic biology
Frontiers in Systems Biology, 2022 Systems and Synthetic Biology are complementary fields emerging side-by-side into mainstream scientific research. Whilst systems biologists focus on understanding natural systems, synthetic biologists wish to modify, adapt and re-purpose biological ...
Robert W. Smith +5 more
doaj +1 more source
Critical assessment of methods of protein structure prediction: Progress and new directions in round XI [PDF]
, 2016 Modeling of protein structure from amino acid sequence now plays a major role in structural biology. Here we report new developments and progress from the CASP11 community experiment, assessing the state of the art in structure modeling. Notable points
Fidelis, Krzysztof +4 more
core +1 more source
Approximate parameter inference in systems biology using gradient matching: a comparative evaluation [PDF]
, 2016 Background: A challenging problem in current systems biology is that of parameter inference in biological pathways expressed as coupled ordinary differential equations (ODEs).
Filippone, Maurizio +4 more
core +1 more source
Data Management and Modeling in Plant Biology
Frontiers in Plant Science, 2021 The study of plant-environment interactions is a multidisciplinary research field. With the emergence of quantitative large-scale and high-throughput techniques, amount and dimensionality of experimental data have strongly increased.
Maria Krantz +6 more
doaj +1 more source
Novel developments in SBGN-ED and applications [PDF]
, 2011 Systems Biology Graphical Notation (SBGN, http://sbgn.org) [1] is an emerging standard for graphical representations of biochemical and cellular processes studied in systems biology.
Anja Hartmann +5 more
core +2 more sources
Hierarchical community structure in complex (social) networks [PDF]
, 2014 The investigation of community structure in networks is a task of great importance in many disciplines, namely physics, sociology, biology and computer science where systems are often represented as graphs.
Bagnoli, Franco, Massaro, Emanuele
core +2 more sources
Reproducible chemostat cultures to minimize eukaryotic viruses from fecal transplant material
iScienceSummary: Recent studies indicate an important role of bacteriophages for successful fecal microbiota transplantation (FMT). However, wider clinical applications of FMT are hampered by to donor variability and concerns of infection risks by bacteria and ...
Signe Adamberg +5 more
doaj +1 more source
Quantitative biology: where modern biology meets physical sciences [PDF]
, 2014 Quantitative methods and approaches have been playing an increasingly important role in cell biology in recent years. They involve making accurate measurements to test a predefined hypothesis in order to compare experimental data with predictions ...
Fai, Thomas G. +5 more
core +2 more sources
Multiplexed CRISPR gene editing in primary human islet cells with Cas9 ribonucleoprotein
iScienceSummary: Successful genome editing in primary human islets could reveal features of the genetic regulatory landscape underlying β cell function and diabetes risk.
Romina J. Bevacqua +6 more
doaj +1 more source