Results 101 to 110 of about 73,680 (292)

Tyrosinase Driven‐Intracellular Polymerization of a Porphyrin Derivative Induced Immunogenic Death of Melanoma Cells and Strengthened Photodynamic Therapy

open access: yesAdvanced Science, EarlyView.
This study uses tyrosinase, which is highly expressed in melanoma, to drive porphyrins to polymerize and self‐assemble within tumor cells to form retented microstructures. This process induces immunogenic death and activates immune responses (M1 macrophages, dendritic cells, CD8+T cells), turning “cold” tumors into “hot” tumors.
Mian Tang   +9 more
wiley   +1 more source

High-pressure bioluminescence system.

open access: yes, 2013
(A) Photography of the high-pressure bioluminescence system and (B) schematic section diagram of the high-pressure bioluminescence tank. PMT: photomultiplier tube; OF: optical fiber; CU: photomultiplier counting unit; T: high-pressure temperature sensor;
Christian Tamburini (278059)   +8 more
core   +1 more source

Bacterial bioluminescence is an important regulator of multitrophic interactions in the soil

open access: yesCell Reports
Summary: Enormous efforts have been made to understand the functions of bioluminescence; however, its relevance in soil ecosystems has barely been investigated.
Arthur Muller   +10 more
doaj   +1 more source

Scalable Engineering of Bio‐Manufactured Extracellular Vesicles for Selective Delivery in Ovarian Cancer Patient‐Derived Models

open access: yesAdvanced Science, EarlyView.
Engineered extracellular vesicles displaying Ephrin‐B2 selectively target Ephrin‐B4–expressing ovarian cancer cells, enabling precise delivery in patient‐derived models. This scalable bio‐manufacturing platform reveals a versatile strategy to exploit Ephrin signaling for highly specific therapeutic payload delivery and motivates exploration of tailored
Nihar Godbole   +17 more
wiley   +1 more source

Allosteric DNAzyme‐Enabled Sensitive and Multiplex Detection of Biomarkers for Rapid Diagnosis of Urinary Tract Infections

open access: yesAdvanced Science, EarlyView.
A catalytic allosteric DNAzyme assay (SMART) is developed by engineering DNAzyme into a unimolecular biosensor, enabling highly sensitive and multiplex detection of small molecules and nucleic acids. SMART enables extraction‐free, one‐pot, one‐step, isothermal, and cost‐effective detection of biological markers, achieving >95% accuracy for rapid ...
Yanzhe Shen   +12 more
wiley   +1 more source

"Classical" applications of chemiluminescence and bioluminescence

open access: yes, 2010
Chemiluminescence and bioluminescence are powerful detection techniques used in such widely different areas as molecular biology, drug discovery, clinical diagnosis, food and hygiene control, environmental and forensic analysis.
RODA, ALDO   +2 more
core  

Cancer‐Associated Fibroblast‐Derived Sphingosine‐1‐Phosphate Activates a MALL–SDC4 Axis to Facilitate Perineural Invasion in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
CAF‐derived S1P activates the S1PR3‐JNK‐Jun signaling pathway, thereby transcriptionally upregulating MALL expression in cancer cells. MALL increases the cell‐surface abundance of SDC4 by promoting its recycling and restricting its lysosomal degradation, which in turn enhances RhoA‐p‐MLC2‐dependent amoeboid invasion and SDC4‐PTN axis‐mediated cancer ...
Wang Peng   +16 more
wiley   +1 more source

Bioluminescence of sharks a case study, Etmopterus spinax

open access: yes, 2008
Bioluminescence arose independently in a wide range of species, from bacteria to fishes, which are the only luminous vertebrates. Consequently, luminescent species demonstrate a great diversity in the structure, in the control, as well as in the function
Mallefet, Jérôme   +2 more
core  

Bioluminescence physiological regulation through photo-perception: an unexpected functional convergent evolution

open access: yes, 2022
Bioluminescence is defined as the production of visible light by a living organism [1] . To fulfil its ecological role (i.e. defense, offense, or communication), bioluminescence needs to be finely controlled.
Duchatelet, Laurent   +4 more
core  

A High‐Throughput Live Imaging Platform to Investigate Circuit‐Dependent Regulation of Circadian Rhythms in Brain Tissue

open access: yesAdvanced Science, EarlyView.
Biological rhythms coordinate physiology, from genes to behavior. Study of circadian rhythms in brain tissue is constrained by limited throughput and spatial and temporal information quality. A new platform for high‐throughput, long‐term multiplexed fluorescent live imaging of circadian rhythms in brain slices is introduced.
Marco Ferrari   +3 more
wiley   +1 more source

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