Results 121 to 130 of about 73,680 (292)

Amplification of Endoplasmic Reticulum Stress via Inhibiting Lipid Droplet Formation to Enhance Chemodynamic Immunotherapy

Advanced Science, EarlyView.
An endoplasmic reticulum (ER)‐targeted chemodynamic nanoagent (TCBQ/iLD‐ER NPs) comprising •OH‐generating tetrachloro‐1,4‐benzoquinone (TCBQ) and lipid droplets (LDs) formation inhibitor (iLD) is developed for chemodynamic immunotherapy of tumors. After ingestion by cancer cells, TCBQ/iLD‐ER NPs preferentially accumulate in the ER and react with ER ...
Huilan Cai, Shaoru Zhuang, Yang Zhu, Rujiang Ao, Meili Yu, Tingting Cui, Jun Wang, Xuegang Niu, Hongwei Huang, Shanshan Peng, Yu He, Lisen Lin, Huanghao Yang   +12 more
wiley   +1 more source

Decoding the Bioluminescent and Non-Bioluminescent Traits of Panellus stipticus: A Genomic and Phenotypic Perspective

Journal of Fungi
The species Panellus stipticus presents a unique situation whereby some geographic strains are bioluminescent while others are not. This study investigates the factors affecting the bioluminescence of P. stipticus, focusing on culture media optimization,
Roel C. Rabara, Xianfa Xie
doaj   +1 more source

Asymmetrically Coordinated Dual‐Atom Manganese Contrast Agents Enabling High‐Efficiency T1 Enhanced MRI for Precise Tumor Visualization

Advanced Science, EarlyView.
A novel dual‐atom manganese MRI contrast agent (Mn‐BN) with a unique asymmetric coordination geometry provided a promising platform for sensitive and specific tumor imaging. In mice model, Mn‐BN nanoparticles precisely functioned as both a primary tumor‐specific enhancer in subcutaneous models and a hepatocyte‐specific agent in liver metastases models ...
Ding Yang, Qing‐Yang Li, Jianli Liang, Gengyou Li, Nan Sun, Qianqian Song, Haitao Zhu, Xiaoting Li, Zechuan Li, Jiankai Dong, Weisheng Guo, Yafang Xiao, Chun‐Sing Lee, Ying‐Shi Sun   +13 more
wiley   +1 more source

Induction of bioluminescence via tamoxifen.

, 2015
To examine the duration of serial injections of tamoxifen free base on joint-specific bioluminescence, we treated mice for 0–5 days via intraperitoneal injection. (A) There is an increase at 3 days (p = 0.004) and from 3 to 5 days (p = 0.01).
Ronald K. June (534844), Ella R. Wardwell (766687), Justin R. Prigge (534842), Sarah E. Mailhiot (766685), Donald L. Zignego (766686), Edward E. Schmidt (248121)   +5 more
core   +1 more source

BCMA‐Engineered Dendritic Cell‐Derived Exosomes as Bi‐Functional Therapeutics Orchestrating Cytokine Sequestration and Immune Activation for Multiple Myeloma

Advanced Science, EarlyView.
A dual‐function cell‐free therapeutic based on DC2.4 cell‐derived exosomes engineered to display BCMA. (Left) Soluble Ligand Sequestration (Decoy Function): DB Exo act as molecular decoys that predominantly sequester soluble APRIL with partial BAFF attenuation, effectively disrupting the NF‐κB survival signaling axis and suppressing myeloma cell ...
Yuqing Zeng, Chao He, Zhibin He, Hongbo Chen, Fang Cheng, Yongjiang Zheng   +5 more
wiley   +1 more source

Bioluminescence as a tool in molecular biology

, 2017
Bioluminescence has been studied for many years by scientists. There are numerous mechanisms of that phenomenon; among them bacterial bioluminescence is the most frequently found in nature.
Katarzyna Pajor, Ilona Bednarek, Daniel Sypniewski   +2 more
core   +1 more source

The Mechanics of Bioluminescence [PDF]

Proceedings of the National Academy of Sciences, 1944
W D, McElroy, R, Ballentine
openaire   +2 more sources

Targeting PLD3 Reverses the Immunosuppressive Niche by Reprogramming Tumor‐Associated Macrophages and Potentiates Antitumor Immunity

Advanced Science, EarlyView.
PLD3 activates the lysosomal‐AKT‐NF‐κB axis to drive cellular senescence in macrophages, establishing an immunosuppressive TME by limiting the infiltration of cytotoxic T, NK, and NKT cells, which confers resistance to anti‐PD‐1 therapy. Abrine inhibits PLD3 expression, restoring antitumor immunity and synergizing with anti‐PD‐1 treatment.
Xingtu Qin, Qiong Li, Xuemei Xu, Yuhan Wu, Yin Zhu, Jieqiong Wu, Yuan Fang, Qiubei Chen, Shuyang Wang, Jiang Yu, Yaping Ye, Hongli Jiao   +11 more
wiley   +1 more source

International Society for Bioluminescence and Chemiluminescence

Scientific organization for the study of bioluminescence and chemiluminescence in all life forms. Promotes application of luminescent chemistry as a biotechnology and analytical tool. Reports society purpose, meetings and membership.

core  

BIOLUMINESCENCE AND CHEMILUMINESCENCE [PDF]

Photochemistry and Photobiology, 1976
J W, Hastings, T, Wilson
openaire   +2 more sources