Results 1 to 10 of about 62,807 (212)

Expression of a multigene mushroom luciferin biosynthesis pathway as a pseudo-polycistron in plants [PDF]

Scientific Reports
Mushroom bioluminescence is based on a luciferin/luciferase cycle that includes four catalytic enzymes and a post-translational modifier phosphopantetheinyl-transferase (NpgA).
David Samson, Natalie S. Thompson, Vijay R. Sheri, Sairam V. Rudrabhatla, Wayne R. Curtis   +4 more
doaj   +2 more sources

A luciferin analogue generating near-infrared bioluminescence achieves highly sensitive deep-tissue imaging

Nature Communications, 2016
D-luciferin is the standard bioluminescent substrate for in vitro and in vivo imaging. Here the authors introduce AkaLumine-HCl, a soluble luciferin analogue with a near-infrared emission maximum, which allows deep tissue imaging at lower concentrations ...
Takahiro Kuchimaru, Satoshi Iwano, Masahiro Kiyama   +2 more
exaly   +2 more sources

Biochemical basis of endogenous bioluminescent springtail Lobella sauteri (Collembola) [PDF]

Biology Open
Manabu Bessho-Uehara, Takumi Kato, Atsuko Ohira, Taizo Nakamori, Yuichi Oba   +4 more
doaj   +2 more sources

Luciferase‐free Luciferin Electrochemiluminescence

Angewandte Chemie International Edition, 2022
AbstractLuciferin is one of Nature's most widespread luminophores, and enzymes that catalyze luciferin luminescence are the basis of successful commercial “glow” assays for gene expression and metabolic ATP formation. Herein we report an electrochemical method to promote firefly's luciferin luminescence in the absence of its natural biocatalyst ...
Mattia Belotti, Mohsen M. T. El‐Tahawy, Li‐Juan Yu, Isabella C. Russell, Nadim Darwish, Michelle L. Coote, Marco Garavelli, Simone Ciampi   +7 more
openaire   +4 more sources

Biosynthesis of firefly luciferin in adult lantern: decarboxylation of L-cysteine is a key step for benzothiazole ring formation in firefly luciferin synthesis. [PDF]

PLoS ONE, 2013
Bioluminescence in fireflies and click beetles is produced by a luciferase-luciferin reaction. The luminescence property and protein structure of firefly luciferase have been investigated, and its cDNA has been used for various assay systems.
Yuichi Oba, Naoki Yoshida, Shusei Kanie, Makoto Ojika, Satoshi Inouye   +4 more
doaj   +1 more source

Biosensing firefly luciferin synthesis in bacteria reveals a cysteine-dependent quinone detoxification route in Coleoptera

Scientific Reports, 2022
Luciferin biosynthetic origin and alternative biological functions during the evolution of beetles remain unknown. We have set up a bioluminescent sensing method for luciferin synthesis from cysteine and benzoquinone using E.
Daniel Rangel de Souza, Jaqueline Rodrigues Silva, Ariele Moreira, Vadim R. Viviani   +3 more
doaj   +1 more source

Sustained Effect of Hyaluronic Acid in Subcutaneous Administration to the Cochlear Spiral Ganglion. [PDF]

PLoS ONE, 2016
The spatiotemporal distribution of drugs in the inner ear cannot be precisely evaluated because of its small area and complex structure. In the present study, we used hyaluronic acid (HA)-dispersed luciferin to image transgenic mice and to determine the ...
Yozo Inagaki, Masato Fujioka, Sho Kanzaki, Kotaro Watanabe, Naoki Oishi, Go Itakura, Akimasa Yasuda, Shinsuke Shibata, Masaya Nakamura, Hirotaka James Okano, Hideyuki Okano, Kaoru Ogawa   +11 more
doaj   +1 more source

New luciferin-based probe substrates for human CYP26A1

Biochemistry and Biophysics Reports, 2020
Activity of human CYP26A1 towards six proluciferin probe substrates and their ester derivatives was monitored. These included three monofluorobenzyl ether isomers and three five-membered heterocycles.
Shishir Sharma, Jingyao Liu, Xue Zhang, Sangeeta Shrestha Sharma, Erik J. Sorensen, Matthias Bureik   +5 more
doaj   +1 more source

Chemistry in Fungal Bioluminescence: Theoretical Studies on Biosynthesis of Luciferin from Caffeic Acid and Regeneration of Caffeic Acid from Oxidized Luciferin

Journal of Fungi, 2023
Fungal bioluminescence is widely distributed in the terrestrial environment. At a specific stage of growth, luminescent fungi shine green light at the fruiting body or mycelium.
Xiayu Liu, Mingyu Wang, Yajun Liu
doaj   +1 more source

Transcriptome analysis reveals candidate genes involved in luciferin metabolism in Luciola aquatilis (Coleoptera: Lampyridae) [PDF]

PeerJ, 2016
Bioluminescence, which living organisms such as fireflies emit light, has been studied extensively for over half a century. This intriguing reaction, having its origins in nature where glowing insects can signal things such as attraction or defense, is ...
Wanwipa Vongsangnak, Pramote Chumnanpuen, Ajaraporn Sriboonlert   +2 more
doaj   +2 more sources