Results 11 to 20 of about 67,421 (349)

Genomic and experimental data provide new insights into luciferin biosynthesis and bioluminescence evolution in fireflies

Scientific Reports, 2020
Fireflies are among the most charismatic insects for their spectacular bioluminescence, but the origin and evolution of bioluminescence remain elusive.
Ru Zhang, Jinwu He, Zhiwei Dong, Guichun Liu, Yuan Yin, Xinying Zhang, Qi Li, Yandong Ren, Yongzhi Yang, Wei Liu, Xianqing Chen, Wenhao Xia, Kang Duan, Fei Hao, Zeshan Lin, Jie Yang, Zhou Chang, Ruoping Zhao, Wenting Wan, Sihan Lu, Yanqiong Peng, Siqin Ge, Wen Wang, Xueyan Li   +23 more
doaj   +2 more sources

New Zealand glowworm (Arachnocampa luminosa) bioluminescence is produced by a firefly-like luciferase but an entirely new luciferin

Scientific Reports, 2018
The New Zealand glowworm, Arachnocampa luminosa, is well-known for displays of blue-green bioluminescence, but details of its bioluminescent chemistry have been elusive.
Oliver C. Watkins, Miriam L. Sharpe, Nigel B. Perry, Kurt L. Krause   +3 more
doaj   +2 more sources

Synthesis and Luminescence Properties of Near-Infrared N-Heterocyclic Luciferin Analogues for In Vivo Optical Imaging [PDF]

Bulletin of the Chemical Society of Japan, 2019
As a means of achieving highly sensitive bioluminescence imaging of deep tissues utilizing the firefly luciferin-luciferase (L-L) reaction, we previously reported a luciferin analogue, AkaLumine, which exhibits high cell-permeability and emits near ...
Masahiro Kiyama, Rika Obata, Ryohei Saito, Satoshi Iwano, Shijia W. Lu, Shinae Kizaka-Kondoh, Shojiro A. Maki, Shoko Higashi, Takahiro Kuchimaru, Takashi Hirano   +9 more
core   +3 more sources

Chemistry in Fungal Bioluminescence: A Theoretical Study from Luciferin to Light Emission.

Journal of Organic Chemistry, 2021
As the only genetically encodable bioluminescent system among eukaryotes to date, bioluminescent fungi can unceasingly emit green light for days.
Ming-yu Wang, Yajun Liu
semanticscholar   +1 more source

How to Select Firefly Luciferin Analogues for In Vivo Imaging

International Journal of Molecular Sciences, 2021
Bioluminescence reactions are widely applied in optical in vivo imaging in the life science and medical fields. Such reactions produce light upon the oxidation of a luciferin (substrate) catalyzed by a luciferase (enzyme), and this bioluminescence ...
Ryohei Saito-Moriya, J. Nakayama, Genta Kamiya, Nobuo Kitada, R. Obata, S. Maki, H. Aoyama   +6 more
semanticscholar   +1 more source

Effects of pentoxifylline on canine platelet aggregation

Veterinary Medicine and Science, 2021
Background Pentoxifylline can decrease platelet function in humans, but the anti‐platelet effects of pentoxifylline in dogs is unknown. The addition of a luciferin–luciferase reagent during platelet aggregometry can induce a dose‐dependent potentiation ...
John M. Thomason, Todd M. Archer, Robert W. Wills, Andrew J. Mackin   +3 more
doaj   +1 more source

Bioluminescent Sensors for Ca++ Flux Imaging and the Introduction of a New Intensity-Based Ca++ Sensor

Frontiers in Bioengineering and Biotechnology, 2021
Sensitive detection of biological events is a goal for the design and characterization of sensors that can be used in vitro and in vivo. One important second messenger is Ca++ which has been a focus of using genetically encoded Ca++ indicators (GECIs ...
Jie Yang, Carl Hirschie Johnson
doaj   +1 more source

Multicomponent Bioluminescence Imaging with a π-Extended Luciferin.

Journal of the American Chemical Society, 2020
Bioluminescence imaging with luciferase-luciferin pairs is commonly used for monitoring biological processes in cells and whole organisms. Traditional bioluminescent probes are limited in scope, though, as they cannot be easily distinguished in ...
Zi Yao, Brendan S Zhang, Rachel C. Steinhardt, J. Mills, Jennifer A. Prescher   +4 more
semanticscholar   +1 more source

Label-free phenotypic profiling identified D-luciferin as a GPR35 agonist. [PDF]

PLoS ONE, 2012
Fluorescent and luminescent probes are essential to both in vitro molecular assays and in vivo imaging techniques, and have been extensively used to measure biological function.
Haibei Hu, Huayun Deng, Ye Fang
doaj   +1 more source

Analysis of the Anticipatory Behavior Formation Mechanism Induced by Methamphetamine Using a Single Hair

Cells, 2023
While the suprachiasmatic nucleus (SCN) coordinates many daily rhythms, some circadian patterns of expression are controlled by SCN-independent systems. These include responses to daily methamphetamine (MAP) injections.
Riku Sato, Megumi Kanai, Yukina Yoshida, Shiori Fukushima, Masahiro Nogami, Takeshi Yamaguchi, Norio Iijima, Kenneth Sutherland, Sanae Haga, Michitaka Ozaki, Kazuko Hamada, Toshiyuki Hamada   +11 more
doaj   +1 more source