Results 31 to 40 of about 67,421 (349)
Bioluminescence imaging in mice with synthetic luciferin analogues.
Luciferase enzymes from bioluminescent organisms can be expressed in mice, enabling these rodents to glow when treated with a corresponding luciferin substrate.
Xincai Ji, Spencer T. Adams, S. Miller
semanticscholar +1 more source
Electrochemically Generated Luminescence of Luminol and Luciferin in Ionic Liquids
Electrochemiluminescence (ECL) is the generation of light triggered by an electrochemical reaction. ECL has been extensively studied in solvent‐based electrolytes, but there is a lack of data on using electrode reactions to populate an excited‐state ...
Mattia Belotti +4 more
doaj +1 more source
Cyclodextrins are well-characterized, barrel-shaped molecules that can solubilize organic small molecules in aqueous solution via host–guest interactions. As such, cyclodextrins are used as excipients for experimental therapeutics in vivo.
Jeyan S. Kumar MSc +3 more
doaj +1 more source
Synthesis of N-peptide-6-amino-D-luciferin Conjugates
A general strategy for the synthesis of N-peptide-6-amino-D-luciferin conjugates has been developed. The applicability of the strategy was demonstrated with the preparation of a known substrate, N-Z-Asp-Glu-Val-Asp-6-amino-D-luciferin (N-Z-DEVD-aLuc).
Anita K. Kovács +8 more
doaj +1 more source
Isolation of Taxol and Flavin-like fluorochrome from Endophytic Fungi of Mangifera indica
Scouting for novel and plant-derived biomolecules from endophytic microbial sources draws greater focus on the discovery of novel bioactive metabolites.
Enthai Ganeshan Jagan +3 more
doaj +1 more source
Core-modified coelenterazine luciferin analogues, synthesis and chemiluminescence properties.
In our work on the design and studies of luciferins related to the blue-hued coelenterazine, we undertook the synthesis of heterocyclic analogues susceptible to produce a photon, possibly at a different wavelength.
Glwadys Gagnot +8 more
semanticscholar +1 more source
Influence of Bioluminescence Imaging Dynamics by D-Luciferin Uptake and Efflux Mechanisms
Bioluminescence imaging (BLI) detects light generated by luciferase-mediated oxidation of substrate and is used widely for evaluating transgene expression in cell-based assays and in vivo in relevant preclinical models.
Yimao Zhang +3 more
doaj +1 more source
First Record of Bioluminescence in a Sipunculan Worm
During a search for bioluminescent marine annelids around the island of Carrie Bow Cay, Belize, we discovered bioluminescence in the sipunculan worm Nephasoma pellucidum. The identification of N. pellucidum was verified by DNA barcoding of ∼650 bp of the
Anderson G. Oliveira +3 more
doaj +1 more source
Circadian disturbance of clock gene expression is a risk factor of diseases like obesity, cancer and sleep disorder. For the study of these diseases, it is necessary to monitor and analyze the expression rhythm of clock genes in the whole body for a long
Kanako Nakajima +8 more
semanticscholar +1 more source
Bioluminescence Imaging of Potassium Ion Using a Sensory Luciferin and an Engineered Luciferase
Bioluminescent indicators are power tools for studying dynamic biological processes. In this study, we present the generation of novel bioluminescent indicators by modifying the luciferin molecule with an analyte-binding moiety.
Shengyu Zhao +5 more
semanticscholar +1 more source

