Results 241 to 250 of about 105,850 (272)

Innovative γ‐Oryzanol and KC2 Based Lipid Nanoparticles: OryKL Platform Provides Safe and Efficient In Vivo mRNA Delivery

Small, EarlyView.
Identified through multi‐stage selection process, a formulation combining γ‐oryzanol and DLin‐KC2‐DMA, termed as OryKL, demonstrates unique nano‐structural features, highly efficient mRNA transfection and functional integrity during long‐term storage, enables broad biodistribution and distinct cell tropism following intravenous administration with no ...
Pengkai Shi, Haikun Liu, Ahmed Refaat, Hung Nguyen, Anne Nguyen, Kaiting Miao, Yuyang Song, Sylvain Trépout, Rico F. Tabor, Liliana de Campo, Karlheinz Peter, Mark Louis P. Vidallon, Xiaowei Wang   +12 more
wiley   +1 more source

Synthetic Multidomain Proteins Containing Unstructured and α‑Helical Linkers Reveal a Differential Impact of Molecular Crowding on Catalytic Activity and Conformation. [PDF]

ACS Omega
Sultana A, Geethakumari AM, Ahmed WS, Biswas KH.   +3 more
europepmc   +1 more source

Single-gene knockout of RNLS or HIVEP2 are insufficient to protect β-cell spheroids from allo- and xeno-rejection. [PDF]

Front Immunol
Karaoglu IC, Odabas A, Önder T, Kizilel S.   +3 more
europepmc   +1 more source

Integrating optical coherence tomography and bioluminescence with predictive modeling for quantitative assessment of methicillin-resistant <i>S. aureus</i> biofilms. [PDF]

J Biomed Opt
Demidov VV, Jackson OP, Demidova N, Gunn JR, Gitajn IL, Elliott JT.   +5 more
europepmc   +1 more source

Rhabdoid tumors as a novel target for PSMA-directed CAR T cell therapy. [PDF]

Mol Ther Oncol
Mitra A, Zhou T, Wu J, Nguyen T, Yu C, Barua A, Huang L, Jiang X, Venkatramani R, Jin MM, He B, Feng Q.   +11 more
europepmc   +1 more source

PolyA tail segmentation improves the stability of the template DNA and increases the translatability of in vitro transcribed mRNA. [PDF]

Nucleic Acids Res
Spiewla T, Czubak K, Pilch Z, Baranowski MR, Krawczyk PS, Affek K, Antczak W, Szulc-Gasiorowska M, Chmielinski S, Mroczek S, Brouze M, Nowis D, Golab J, Dziembowski A, Jemielity J, Kowalska J.   +15 more
europepmc   +1 more source

Bioluminescence

, 1969
openaire   +1 more source

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Bioluminescence-Optogenetics

2021
In this chapter, we introduce a relatively new, emerging method for molecular neuromodulation-bioluminescence-optogenetics. Bioluminescence-optogenetics is mediated by luminopsin fusion proteins-light-sensing opsins fused to light-emitting luciferases.
Ken, Berglund, Matthew A, Stern, Robert E, Gross   +2 more
openaire   +2 more sources

BIOLUMINESCENCE

Annual Review of Cell and Developmental Biology, 1998
▪ Abstract  Bioluminescence has evolved independently many times; thus the responsible genes are unrelated in bacteria, unicellular algae, coelenterates, beetles, fishes, and others. Chemically, all involve exergonic reactions of molecular oxygen with different substrates (luciferins) and enzymes (luciferases), resulting in photons of visible light ...
T, Wilson, J W, Hastings
openaire   +2 more sources

Chemi- and bioluminescence: Bioluminescence

2023
This chapter give examples of theoretical and computational investigations for a better understanding of bioluminescent systems. In bioluminescent systems, the oxidation of substrate inside a protein leads to a product (a light emitter) in its first excited state. Light is emitted with the radiative relaxation of the light emitter.
openaire   +2 more sources