Results 71 to 80 of about 113,231 (318)

Immunogenicity of targeted lentivectors [PDF]

, 2014
To increase the safety and possibly efficacy of HIV-1 derived lentivectors (LVs) as an anti-cancer vaccine, we recently developed the Nanobody (Nb) display technology to target LVs to antigen presenting cells (APCs).
Adotévi, Bennett, Bevan, Bhardwaj, Bhardwaj, Bhardwaj, Blander, Bonehill, Bonehill, Breckpot, Breckpot, Breckpot, Charleston, Chuah, Collins, Collins, Collins, Collins, Cosset, Diebold, Donckier, Eggermont, Enk, Figdor, Gajewski, Garcia, Groettrup, Inaba, Kast, Lahoutte, Lévy, McCullough, Medzhitov, Melief, Mellman, Mortha, Moser, Moser, Munn, Naldini, Neyns, Noguiez-Hellin, Nussenzweig, Palena, Raes, Reis e Sousa, Reiser, Reiser, Richardson, Romani, Roncarolo, Sakuma, Schroyens, Semesyuk, Song, Storm, Thielemans, Thielemans, Thielemans, Thielemans, Torretta, Turk, Van Kooyk, Wang, Wang, Yamaguchi, Yewdell, Yu   +67 more
core   +3 more sources

Intrinsically Disordered Protein‐Inspired Nanovector‐Based Coacervates for the Direct Cytosolic Transport of Biomacromolecules

Advanced Materials, EarlyView.
Intrinsically disordered protein‐inspired nanovectors (IDP‐NVs) form stable nanocoacervates (NCs) with diverse biomacromolecules. In situ conformational changes confer stability and adaptability to NCs under dynamically changing physiological conditions.
Soyeong Jin, Hyemin Park, Seuk‐Min Ryu, Dagyeong Guk, Jaeeun Lee, Seongeon Jin, Changjoon Keum, Jinyoung Park, Myoung‐Hwan Park, Chaekyu Kim, Hojun Kim, Jaegeun Noh, Kwan Hyi Lee, Ja‐Hyoung Ryu, Youngdo Jeong   +14 more
wiley   +1 more source

A method for capturing images of Collembola bioluminescence using a smartphone camera

Soil Organisms
Although bioluminescence in Collembola has been known since 1851, photographic evidence remains sparse. Photographs serve as essential evidence to confirm bioluminescence and facilitate further investigations into this phenomenon.
Atsuko Ohira, Taizo Nakamori
doaj   +1 more source

Voluntary exercise can strengthen the circadian system in aged mice [PDF]

, 2013
Consistent daily rhythms are important to healthy aging according to studies linking disrupted circadian rhythms with negative health impacts. We studied the effects of age and exercise on baseline circadian rhythms and on the circadian system's ability ...
A Davidson, A Power, A Watanabe, AA Kondratova, AC King, AJ Davidson, AJ Davidson, B Rusak, C Castillo, CJ Guenthner, DE Kolker, DF Swaab, DJ Buysse, DJ Dijk, DJ Foley, DJ Foley, E Satinoff, E. Zimmerman, EK Baehr, F Aujard, G. S. Lall, GJ Tranah, GS Passos, H Albus, H Li, H. Queenan, HT vanderLeest, I. Song, IN Karatsoreos, J Schaap, K Cho, KJ Reid, M Asai, M Harrington, M Münch, M Nagano, M Palomba, M. E. Harrington, MA Grandner, MJ Duncan, MJ Duncan, MU Gillette, MW Greene, MW Marlatt, N Mrosovsky, O Castanon-Cervantes, P. C. Molyneux, PC Yannielli, RD Nebes, S Ancoli-Israel, S Benloucif, S Farajnia, S Kiessling, S Yamazaki, S Yamazaki, S Yamazaki, S. M. Biello, SH Yoo, SJ Aton, SM Biello, T Deboer, T Yoshikawa, T. L. Leise, TA Bedrosian, TA Martino, TA Martino, TJ Nakamura, TL Leise, U Abraham, U Albrecht, VS Valentinuzzi, W Nakamura, Y Tahara, Y Zhang, Y Zhang   +74 more
core   +2 more sources

Sculpting the Future of Bone: The Evolution of Absorbable Materials in Orthopedics

Advanced Materials, EarlyView.
This review summarizes the current status of polymeric, ceramic, and metallic absorbable materials in orthopedic applications, and highlights several innovative strategies designed to enhance mechanical performance, control degradation, and promote bioactivity. We also discuss the progress and translational potential of absorbable materials in treating
Zhao Wang, Zehui Lv, Xuejie Cai, Yingjie Wang, Bo Peng, Haojing Xu, Hualuo Pang, Xingdong Yang, Jiawei Xu, Yixin Bian, Bin Feng, Peng Wen, Yufeng Zheng, Xisheng Weng   +13 more
wiley   +1 more source

Controlled Release of Vancomycin and Tigecycline from an Orthopaedic Implant Coating Prevents Staphylococcus aureus Infection in an Open Fracture Animal Model. [PDF]

, 2019
Introduction:Treatment of open fractures routinely involves multiple surgeries and delayed definitive fracture fixation because of concern for infection.
Bernthal, NM, Hegde, V, Loftin, AH, Niska, J, Segura, T, Stavrakis, AI, Weixian, X, Zhu, S   +7 more
core  

Mathematical model of the Lux luminescence system in the terrestrial bacterium Photorhabdus luminescens. [PDF]

, 2009
A mathematical model of the Lux luminescence system, governed by the operon luxCDABE in the terrestrial bacterium Photorhabdus luminescens, was constructed using a set of coupled ordinary differential equations.
Stekel, Dov J, Welham, Patricia A
core   +1 more source

Mitochondria‐Targeted Nanomotor: H2S‐Driven Cascade Therapy for Hepatocellular Carcinoma

Advanced Materials, EarlyView.
A mitochondrial‐targeted nanomotor integrates photodynamic therapy, mild photothermal therapy, and enzyme dynamic therapy into a self‐amplifying cascade through H2S‐driven metabolic reprogramming. Abstract Despite advances in combination therapies for cancer treatment, most strategies rely on modular‐additive designs that lack dynamic molecular cues to
Chengcheng Li, Xiaodong Ma, Shiji Fang, Biao Chen, Xinru Wang, Lingyun He, Xin Yang, Yuanqiang Li, Jessica M. Rosenholm, Zhongwei Zhao, Jiansong Ji, Hongbo Zhang   +11 more
wiley   +1 more source

Focal Spot, Spring 2009 [PDF]

, 2009
https://digitalcommons.wustl.edu/focal_spot_archives/1111/thumbnail ...

core   +1 more source

Phase transitions in single neurons and neural populations: Critical slowing, anesthesia, and sleep cycles [PDF]

, 2010
The firing of an action potential by a biological neuron represents a dramatic transition from small-scale linear stochastics (subthreshold voltage fluctuations) to gross-scale nonlinear dynamics (birth of a 1-ms voltage spike). In populations of neurons
Sleigh, James W., Steyn-Ross, D. Alistair, Steyn-Ross, Moira L., Wilson, Marcus T.   +3 more
core   +2 more sources