Results 241 to 250 of about 6,926,142 (285)
Novel NanoLuc substrates enable bright two-population bioluminescence imaging in animals
Nature Methods, 2020 Sensitive detection of two biological events in vivo has long been a goal in bioluminescence imaging. Antares, a fusion of the luciferase NanoLuc to the orange fluorescent protein CyOFP, has emerged as a bright bioluminescent reporter with orthogonal ...
Yichi Su +2 more
exaly +2 more sources
Some of the next articles are maybe not open access.
Related searches:
Related searches:
Advanced Functional Materials, 2021
Optical imaging has played a pivotal role in deciphering in vivo bioinformatics but is limited by shallow penetration depth and poor imaging performance owing to interfering tissue autofluorescence induced by concurrent photoexcitation.
Xiaozhen Li +4 more
semanticscholar +1 more source
Optical imaging has played a pivotal role in deciphering in vivo bioinformatics but is limited by shallow penetration depth and poor imaging performance owing to interfering tissue autofluorescence induced by concurrent photoexcitation.
Xiaozhen Li +4 more
semanticscholar +1 more source
In Vivo Molecular Bioluminescence Imaging: New Tools and Applications
Trends in Biotechnology, 2017 Laura Mezzanotte +2 more
exaly +2 more sources
ACS Nano, 2019
Inflammation is an immunological response involved in various inflammatory disorders ranging from neurodegenerative diseases to cancers. Luminol has been reported to detect myeloperoxidase (MPO) activity in an inflamed area through a light-emitting ...
Zhifei Dai, Renfa Liu, Yunxue Xu
exaly +2 more sources
Inflammation is an immunological response involved in various inflammatory disorders ranging from neurodegenerative diseases to cancers. Luminol has been reported to detect myeloperoxidase (MPO) activity in an inflamed area through a light-emitting ...
Zhifei Dai, Renfa Liu, Yunxue Xu
exaly +2 more sources
Red-shifted luciferase–luciferin pairs for enhanced bioluminescence imaging
Nature Methods, 2017 Red-shifted bioluminescence reporters are desirable for biological imaging. We describe the development of red-shifted luciferins based on synthetic coelenterazine analogs and corresponding mutants of NanoLuc that enable bright bioluminescence.
Huiwang Ai, Hsien Wei Yeh
exaly +2 more sources
Recent achievements of bioluminescence imaging based on firefly luciferin-luciferase system.
European journal of medicinal chemistry, 2020Bioluminescence imaging (BLI) is a newly developed noninvasive visual approach which facilitates the understanding of a plethora of biological processes in vitro and in vivo due to the high sensitivity, resolution and selectivity, low background signal ...
Shufeng Li +3 more
semanticscholar +1 more source
Bioluminescent Imaging in Bone
2008Monitoring gene expression in vitro and in vivo, is crucial when analyzing osteogenesis and developing effective bone gene therapy protocols. Until recently, molecular analytical tools were only able to detect protein expression either in vitro or in vivo.
Yoram, Zilberman +4 more
openaire +2 more sources
Bioluminescence imaging in living organisms
Current Opinion in Biotechnology, 2005Luciferase enzymes catalyze the emission of light from a substrate -- a phenomenon known as bioluminescence -- and have been employed as reporters of many biological functions. Luminescent reporters are much dimmer than fluorescent reporters, and therefore provide relatively modest spatial and temporal resolution. Yet, they are generally more sensitive
David K, Welsh, Steve A, Kay
openaire +2 more sources
Bioorthogonal chemistry in bioluminescence imaging
Drug Discovery Today, 2018Bioorthogonal chemistry has developed significant over the past few decades, to the particular benefit of molecular imaging. Bioluminescence imaging (BLI) along with other imaging modalities have significantly benefitted from this chemistry. Here, we review bioorthogonal reactions that have been used to signific antly broaden the application range of ...
Aurélien Godinat +2 more
openaire +3 more sources
In Vivo Imaging of Bioluminescent Leptospires
2020The study of pathological processes is often limited to in vitro or ex vivo assays, while understanding pathogenesis of an infectious disease requires in vivo analysis. The use of pathogens, genetically modified to express with luminescent enzymes, combined to charge-coupled device (CCD) cameras, constitutes a major technological advance for assessing ...
Vernel-Pauillac, Frédérique +1 more
openaire +3 more sources