Results 81 to 90 of about 44,745 (290)

Generation of bright autobioluminescent bacteria by chromosomal integration of the improved lux operon ilux2

Scientific Reports, 2022
The bacterial bioluminescence system enables the generation of light by living cells without the requirement of an external luciferin. Due to the relatively low light emission, many applications of bioluminescence imaging would benefit from an increase ...
Carola Gregor
doaj   +1 more source

Bioluminescent imaging of Trypanosoma cruzi infection [PDF]

International Journal for Parasitology, 2008
Chagas disease, caused by infection with the protozoan parasite Trypanosoma cruzi, is a major public health problem in Central and South America. The pathogenesis of Chagas disease is complex and the natural course of infection is not completely understood. The recent development of bioluminescence imaging technology has facilitated studies of a number
Kenneth V, Hyland, Sofya H, Asfaw, Cheryl L, Olson, Melvin D, Daniels, David M, Engman   +4 more
openaire   +2 more sources

Inhibition of SIRT7 Overcomes Radioresistance in Pancreatic Neuroendocrine Tumors by Reactivating MEN1 Expression

Advanced Science, EarlyView.
Pancreatic neuroendocrine tumors frequently silence MEN1 through epigenetic mechanisms. Here, SIRT7 recruits DNMT1 to the MEN1 promoter, drives hypermethylation, and enhances DNA repair. Inhibiting SIRT7 restores MEN1, reduces MRN complex abundance, impairs double‐strand break repair, and sensitizes PanNET models to radiation, supporting SIRT7 as a ...
Jianyun Jiang, Yan Wang, Yi Qin, Luohai Chen, Xiaowu Xu, Guixiong Fan, Desheng Jing, Miaoyan Wei, Xianjun Yu, Junfeng Xu, Shunrong Ji, Jie Chen   +11 more
wiley   +1 more source

In Vivo Visualization and Monitoring of Viable Neural Stem Cells Using Noninvasive Bioluminescence Imaging in the 6-Hydroxydopamine-Induced Mouse Model of Parkinson Disease

Molecular Imaging, 2013
Transplantation of neural stem cells (NSCs) has been proposed as a treatment for Parkinson disease (PD). The aim of this study was to monitor the viability of transplanted NSCs expressing the enhanced luciferase gene in a mouse model of PD in vivo.
Hyung-Jun Im, Do Won Hwang, Han Kyu Lee, Jaeho Jang, Song Lee, Hyewon Youn, Yeona Jin, Seung U. Kim, E. Edmund Kim, Yong Sik Kim, Dong Soo Lee   +10 more
doaj   +1 more source

Bioluminescent imaging of Trypanosoma cruzi infection in Rhodnius prolixus

Parasites & Vectors, 2012
Background Usually the analysis of the various developmental stages of Trypanosoma cruzi in the experimentally infected vertebrate and invertebrate hosts is based on the morphological observations of tissue fragments from animals and insects.
Henriques Cristina, Castro Daniele P, Gomes Leonardo HF, Garcia Eloi S, de Souza Wanderley   +4 more
doaj   +1 more source

Comparison of Image Restoration Methods for Bioluminescence Imaging [PDF]

, 2008
Bioluminescence imaging is a recent modality to visualize biological effects, especially for small animals. However, the acquired images are degraded by diffusion and absorption phenomena from the tissue and by the acquisition system itself. In this paper, we use restoration methods to enhance the quality of bioluminescence images.
Smaïl Akkoul, Roger Lédée, Remy Leconge, Christophe Léger, Rachid Harba, Sabrina Pesnel, Stéphanie Lerondel, Alain Lepape, Luis Vilcahuaman   +8 more
openaire   +1 more source

Optimisation of acquisition time in bioluminescence imaging

, 2015
Decreasing the acquisition time in bioluminescence imaging (BLI) and bioluminescence tomography (BLT) will enable animals to be imaged within the window of stable emission of the bioluminescent source, a higher imaging throughput and minimisation of the ...
Glinton, Sophie, Iain B. Styles, Styles, Iain B.; id_orcid, Mark Cobbold, Suzannah K. G. Mason, Taylor, Shelley L., Sophie Glinton, Dehghani, Hamid; id_orcid, Shelley L. Taylor, Hamid Dehghani, Cobbold, Mark, Mason, Suzannah K. G.   +11 more
core   +1 more source

Tumor‐Derived LAMB3 Drives Immunosuppressive LRRC15+ Fibroblast Formation During Pancreatic Ductal Adenocarcinoma Development

Advanced Science, EarlyView.
A single‐cell atlas of pancreatic ductal adenocarcinoma development reveals progressive ductal‐fibroblast‐immune crosstalk. Tumor‐derived LAMB3 drives the formation of immunosuppressive LRRC15+ fibroblasts through the ITGB1/FAK/MAPK/FOSL2 signaling. Glycolytic reprogramming upregulates LAMB3 and correlates with LRRC15+ fibroblast enrichment.
Xuqing Shi, Hangqi Liu, Jianru Sun, Xiaoding Liu, Xinping Jv, Longyun Chen, Yuhan Zhang, Hui Zhang, Xudong Xing, Ruiyu Li, Xinyi Ke, Jun Wang, Xianglin Yin, Bohan Liu, Qixian Liu, Yuan Wang, Junliang Lu, Shiyi Liu, Junyi Pang, Yumeng Cai, Menghua Dai, Fan Bai, Huanwen Wu, Zhiyong Liang   +23 more
wiley   +1 more source

Identification of the control region of pancreatic expression of Bmp4 in vitro and in vivo. [PDF]

PLoS ONE, 2013
Bone morphogenetic protein 4 (Bmp4) was recently shown to be related to glucose homeostasis in mouse adult pancreas through the regulation of insulin production.
Mayu Yasunaga, Eiji Masui, Asami Oji, Atsumi Soma, Mitsuhiko Osaki, Tomoko Nakanishi, Kenzo Sato   +6 more
doaj   +1 more source

Bioluminescence imaging tools for visualizing cellular processes

, 2023
Bioluminescence is a sensitive technique for imaging biological features over time. This technique relies on the oxidation of a small molecule luciferin by a luciferase enzyme to produce light.
Navarro, Mariana Xotchitl
core