Results 1 to 10 of about 1,725,821 (256)
Haptoglobin as a Biomarker [PDF]
Biochemistry (Moscow), Supplement Series B: Biomedical Chemistry, 2021 Haptoglobin (Hp) is a blood plasma glycoprotein that binds free hemoglobin (Hb) and plays a critical role in tissue protection and the prevention of oxidative damage. In addition, it has a number of regulatory functions. Haptoglobin is an acute phase protein, its concentration in plasma changes in pathology, and the test for its concentration is ...
Naryzny, S. N., Legina, O. K.
openaire +4 more sources
Heart Failure Clinics, 2012 Biomarkers are characteristics objectively measured and evaluated as indicators of: normal biologic processes, pathogenic processes, or pharmacologic response(s) to a therapeutic intervention. In environmental research and risk assessment, biomarkers are frequently referred to as indicators of human or environmental hazards.
Harmony, Larson +3 more
+7 more sources
Biomarkers of Cholestasis [PDF]
Biomarkers in Medicine, 2021 Cholestasis is a major pathological manifestation, often resulting in detrimental liver conditions, which occurs in a variety of indications collectively termed cholestatic liver diseases. The frequent asymptomatic character and complexity of cholestasis, together with the lack of a straightforward biomarker, hampers early detection and treatment of ...
Pieters, Alanah +5 more
openaire +4 more sources
Scientific Reports, 2022 Cellular profiling with multiplexed immunofluorescence (MxIF) images can contribute to a more accurate patient stratification for immunotherapy. Accurate cell segmentation of the MxIF images is an essential step.
Wenchao Han +3 more
doaj +1 more source
Immune microenvironment characteristics in multiple myeloma progression from transcriptome profiling
Frontiers in Oncology, 2022 Multiple myeloma (MM) is characterized by clonal expansion of malignant plasma cells in the bone marrow (BM). Despite the significant advances in treatment, relapsed and refractory MM has not yet been completely cured due to the immune dysfunction in the
Jin Wang +6 more
doaj +1 more source
An Empirical Biomarker-based Calculator for Autosomal Recessive Polycystic Kidney Disease - The Nieto-Narayan Formula [PDF]
, 2016 Autosomal polycystic kidney disease (ARPKD) is associated with progressive enlargement of the kidneys fuelled by the formation and expansion of fluid-filled cysts.
Goldberg, Itzhak D. +3 more
core +18 more sources
Biomarker profiles of acute heart failure patients with a mid-range ejection fraction [PDF]
, 2017 OBJECTIVES: In this study, the authors used biomarker profiles to characterize differences between patients with acute heart failure with a midrange ejection fraction (HFmrEF) and compare them with patients with a reduced (heart failure with a ...
Bloomfield, Daniel M +16 more
core +7 more sources
Breast Cancer Research, 2021 Background The extent of cellular heterogeneity in breast cancer could have potential impact on diagnosis and long-term outcome. However, pathology evaluation is limited to biomarker immunohistochemical staining and morphology of the bulk cancer.
Alison Min-Yan Cheung +8 more
doaj +1 more source
Imaging Biomarkers or Biomarker Imaging? [PDF]
Pharmaceuticals, 2014 Since biomarker imaging is traditionally understood as imaging of molecular probes, we highly recommend to avoid any confusion with the previously defined term “imaging biomarkers” and, therefore, only use “molecular probe imaging (MPI)” in that context. Molecular probes (MPs) comprise all kinds of molecules administered to an organism which inherently
Markus Mitterhauser, Wolfgang Wadsak
openaire +3 more sources
Early and strong antibody responses to SARS-CoV-2 predict disease severity in COVID-19 patients
Journal of Translational Medicine, 2022 Background Antibody response to SARS-CoV-2 is a valuable biomarker for the assessment of the spread of the virus in a population and evaluation of the vaccine candidates. Recent data suggest that antibody levels also may have a prognostic significance in
Jānis Plūme +5 more
doaj +1 more source