Results 101 to 110 of about 1,164,667 (298)
Frontiers in Cellular and Infection MicrobiologyBackgroundNumerous bacteria are involved in the etiology of bacterial vaginosis (BV). Yet, current tests only focus on a select few. We therefore designed a new test targeting 22 BV-relevant species.MethodsUsing 946 stored vaginal samples, a new qPCR ...
Ayodeji B. Oyenihi +7 more
doaj +1 more source
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
EJNMMI Research, 2017 Background Mitochondrial dysfunction is one of the main causes of non-alcohol fatty liver disease (NAFLD). [18F]-BMS-747158-02 (18F-BMS) which was originally developed as a myocardial perfusion imaging agent was reported to bind mitochondrial complex-1 ...
Takemi Rokugawa +5 more
doaj +1 more source
AIM-Harvard/foundation-cancer-image-biomarker: v1
<h2>What's Changed</h2> <ul> <li>Added autopublish workflow by @surajpaib in https://github.com/AIM-Harvard/foundation-cancer-image-biomarker/pull/281</li> <li>Update code for additions - rev1 by @surajpaib in https ...
Ibrahim Hadzic, Suraj Pai, actions-user
core +1 more source
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
EBioMedicine, 2018 Immunotherapeutic agents have demonstrated encouraging signs of clinical utility in non-Hodgkin lymphoma. The goal of this study is to analyze the immune characteristics of Chinese patients with diffuse large B-cell lymphoma (DLBCL) to inform the ...
Peng-peng Xu +17 more
doaj +1 more source
AIM-Harvard/foundation-cancer-image-biomarker: v1.0
<h2>What's Changed</h2> <ul> <li>Added autopublish workflow by @surajpaib in https://github.com/AIM-Harvard/foundation-cancer-image-biomarker/pull/281</li> <li>Update code for additions - rev1 by @surajpaib in https ...
Ibrahim Hadzic, Suraj Pai, actions-user
core +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Molecular characterization of breast cancer CTCs associated with brain metastasis
Nature Communications, 2017 Characterization of CTCs derived from breast cancer patients with brain metastasis (BCBM) may allow for early diagnosis of brain metastasis and/or help for treatment choice and its efficacy.
Debasish Boral +10 more
doaj +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source