Results 51 to 60 of about 1,312,400 (160)
Imaging biomarker roadmap for cancer studies
Nature Reviews Clinical Oncology, 2016 Imaging biomarkers (IBs) are integral to the routine management of patients with cancer. IBs used daily in oncology include clinical TNM stage, objective response and left ventricular ejection fraction.
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Infection & Chemotherapy, 2014 Sepsis remains a leading cause of death in critically ill patients, despite efforts to improve patient outcome. Thus far, no magic drugs exist for severe sepsis and septic shock. Instead, early diagnosis and prompt initial management such as early goal-directed therapy are key to improve sepsis outcome. For early detection of sepsis, biological markers
Jung-Hyun Choi, Sung-Yeon Cho
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International Journal of Ophthalmology, 2020 Retinoblastoma (RB) is the most common intraocular malignancy of childhood caused by inactivation of the Rb genes. The prognosis of RB is better with an earlier diagnosis. Many diagnostic approaches and appropriate clinical treatments have been developed to improve clinical outcomes. However, limitations exist when utilizing current methods.
Qing Shao +4 more
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Revisiting biomarker discovery by plasma proteomics
Molecular Systems Biology, 2017 Clinical analysis of blood is the most widespread diagnostic procedure in medicine, and blood biomarkers are used to categorize patients and to support treatment decisions.
Philipp E. Geyer +3 more
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Analytical and Bioanalytical Chemistry, 2011 Boguslaw, Buszewski, Jochen, Schubert
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Wearable chemical sensors for biomarker discovery in the omics era
Nature Reviews Chemistry, 2022 J. Sempionatto +4 more
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Exosomal tRNA-derived small RNA as a promising biomarker for cancer diagnosis
Molecular Cancer, 2019 tRNA-derived small RNA (tsRNA) is a novel regulatory small non-coding RNA and participates in diverse physiological and pathological processes. However, the presence of tsRNAs in exosome and their diagnostic potential remain unclear.
Lei Zhu +11 more
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Blood GFAP as an emerging biomarker in brain and spinal cord disorders
Nature Reviews Neurology, 2022 A. Abdelhak +13 more
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Locus coeruleus imaging as a biomarker for noradrenergic dysfunction in neurodegenerative diseases
Brain : a journal of neurology, 2019 The locus coeruleus is the site of the earliest pathological changes in many neurodegenerative diseases. Betts et al. describe how in vivo locus coeruleus imaging can be used as a biomarker for noradrenergic dysfunction in neurodegenerative diseases, and
M. Betts +41 more
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Critical Reviews in Clinical Laboratory Sciences, 2013 Sepsis is an unusual systemic reaction to what is sometimes an otherwise ordinary infection, and it probably represents a pattern of response by the immune system to injury. A hyper-inflammatory response is followed by an immunosuppressive phase during which multiple organ dysfunction is present and the patient is susceptible to nosocomial infection ...
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