Results 51 to 60 of about 2,295,331 (380)

Biomarkers of coronary endothelial health: correlation with invasive measures of collateral function, flow and resistance in chronically occluded coronary arteries and the effect of recanalization [PDF]

, 2016
Objectives: In the presence of a chronically occluded coronary artery, the collateral circulation matures by a process of arteriogenesis; however, there is considerable variation between individuals in the functional capacity of that collateral network ...
Alamgir, Farquad, Cunnington, Michael S., Ettelaie, Camille, Hoye, Angela, Ladwiniec, Andrew, Rossington, Jennifer, Thackray, Simon   +6 more
core   +1 more source

Blood-brain barrier breakdown is an early biomarker of human cognitive dysfunction

Nature Network Boston, 2018
Vascular contributions to cognitive impairment are increasingly recognized1–5 as shown by neuropathological6,7, neuroimaging4,8–11, and cerebrospinal fluid biomarker4,12 studies.
D. Nation, Melanie D. Sweeney, Axel Montagne, A. Sagare, Lina M. D’Orazio, M. Pachicano, F. Sepehrband, Amy R. Nelson, David P. Buennagel, M. Harrington, T. Benzinger, A. Fagan, J. Ringman, L. Schneider, J. Morris, H. Chui, Meng Law, A. Toga, B. Zlokovic   +18 more
semanticscholar   +1 more source

miR-21: a non‐specific biomarker of all maladies

Biomarker Research, 2021
miRNA-21 is among the most abundant and highly conserved microRNAs (miRNAs) recognized. It is expressed in essentially all cells where it performs vital regulatory roles in health and disease.
A. Jenike, M. Halushka
semanticscholar   +1 more source

Patient-derived organoids as a predictive biomarker for treatment response in cancer patients

npj Precision Oncology, 2021
Effective predictive biomarkers are needed to enable personalized medicine and increase treatment efficacy and survival for cancer patients, thereby reducing toxic side effects and treatment costs.
G. Wensink, S. Elias, J. Mullenders, M. Koopman, S. Boj, O. Kranenburg, J. Roodhart   +6 more
semanticscholar   +1 more source

Quantitative Comparison of Conventional and t-SNE-guided Gating Analyses

Frontiers in Immunology, 2019
Dimensionality reduction using the t-Distributed Stochastic Neighbor Embedding (t-SNE) algorithm has emerged as a popular tool for visualizing high-parameter single-cell data.
Shadi Toghi Eshghi, Amelia Au-Yeung, Chikara Takahashi, Christopher R. Bolen, Maclean N. Nyachienga, Sean P. Lear, Cherie Green, W. Rodney Mathews, William E. O'Gorman   +8 more
doaj   +1 more source

‘Long-COVID’: a cross-sectional study of persisting symptoms, biomarker and imaging abnormalities following hospitalisation for COVID-19

Thorax, 2020
Large numbers of people are being discharged from hospital following COVID-19 without assessment of recovery. In 384 patients (mean age 59.9 years; 62% male) followed a median 54 days post discharge, 53% reported persistent breathlessness, 34% cough and ...
S. Mandal, J. Barnett, S. Brill, Jeremy S. Brown, E. Denneny, S. Hare, M. Heightman, T. Hillman, J. Jacob, H. Jarvis, M. Lipman, S. Naidu, A. Nair, J. Porter, G. Tomlinson, J. Hurst   +15 more
semanticscholar   +1 more source

The tale of TILs in breast cancer: A report from The International Immuno-Oncology Biomarker Working Group

npj Breast Cancer, 2021
The advent of immune-checkpoint inhibitors (ICI) in modern oncology has significantly improved survival in several cancer settings. A subgroup of women with breast cancer (BC) has immunogenic infiltration of lymphocytes with expression of programmed ...
K. El Bairi, H. R. Haynes, E. Blackley, S. Fineberg, J. Shear, Sophia Turner, Juliana Ribeiro de Freitas, Daniel G Sur, L. C. Amendola, M. Gharib, A. Kallala, I. Arun, Farid Azmoudeh-Ardalan, L. Fujimoto, L. Sua, Shiwei Liu, H. Lien, Pawan Kirtani, M. Balancin, Hicham El Attar, Prerna Guleria, Wenxian Yang, Emad Shash, I. Chen, V. Bautista, Jose Fernando Prado Moura, B. Rapoport, C. Castañeda, E. Spengler, Gabriela Acosta-Haab, I. Frahm, Joselyn Sanchez, Miluska Castillo, Najat Bouchmaa, R. R. Md Zin, R. Shui, T. Onyuma, Wentao Yang, Z. Husain, K. Willard-Gallo, A. Coosemans, E. Perez, E. Provenzano, P. G. Ericsson, E. Richardet, R. Mehrotra, Sandra Sarancone, A. Ehinger, D. Rimm, J. Bartlett, G. Viale, C. Denkert, A. Hida, C. Sotiriou, S. Loibl, S. Hewitt, S. Badve, W. Symmans, Rim S. Kim, G. Pruneri, S. Goel, P. Francis, G. Inurrigarro, R. Yamaguchi, H. García-Rivello, H. Horlings, S. Afqir, R. Salgado, S. Adams, M. Kok, M. Dieci, S. Michiels, S. Demaria, S. Loi, The International Immuno-Oncology Biomarker Working Group   +74 more
semanticscholar   +1 more source

Smell dysfunction: a biomarker for COVID‐19

International Forum of Allergy and Rhinology, 2020
Severe acute respiratory syndrome‐coronavirus‐2 (SARS‐CoV‐2), the virus that causes coronavirus disease 2019 (COVID‐19), is responsible for the largest pandemic since the 1918 influenza A virus subtype H1N1 influenza outbreak.
S. T. Moein, S. Hashemian, Babak Mansourafshar, Ali Khorram-Tousi, P. Tabarsi, R. Doty   +5 more
semanticscholar   +1 more source

Toward a Topology-Based Therapeutic Design of Membrane Proteins: Validation of NaPi2b Topology in Live Ovarian Cancer Cells

Frontiers in Molecular Biosciences, 2022
NaPi2b is a sodium-dependent phosphate transporter that belongs to the SLC34 family of transporters which is mainly responsible for phosphate homeostasis in humans.
Leisan Bulatova, Daria Savenkova, Alsina Nurgalieva, Daria Reshetnikova, Arina Timonina, Vera Skripova, Mikhail Bogdanov, Mikhail Bogdanov, Ramziya Kiyamova   +8 more
doaj   +1 more source

A network analysis to compare biomarker profiles in patients with and without diabetes mellitus in acute heart failure [PDF]

, 2017
Aims: It is unclear whether distinct pathophysiological processes are present among patients with acute heart failure (AHF), with and without diabetes.
Bloomfield, Daniel M., Cleland, John G.F., Cotter, Gad, Davison, Beth A., Demissei, Biniyam G., Dittrich, Howard, Ezekowitz, Justin A., Givertz, Michael M., Hillege, Hans L., Khan, Mohsin A.F., Metra, Marco, O'Connor, Christopher M., Ponikowski, Piotr, Sharma, Abhinav, Teerlink, John R., Tromp, Jasper, van Veldhuisen, Dirk J., Voors, Adriaan A.   +17 more
core   +2 more sources