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Bronchiectasis is a heterogeneous disease with multiple aetiologies and diverse clinical features. There is a general consensus that optimal treatment requires precision medicine approaches focused on specific treatable disease characteristics, known as treatable traits.
Johnson, Emma+2 more
openaire +4 more sources
The Challenges of Tumor Mutational Burden as an Immunotherapy Biomarker.
D. Jardim+3 more
semanticscholar +1 more source
Epigenetics of colorectal cancer: biomarker and therapeutic potential
G. Jung+4 more
semanticscholar +1 more source
Biomarker definitions and their applications
R. Califf
semanticscholar +1 more source
Biomarker selection in R: the BioMark package [PDF]
BioMark is an R package implementing two meta-strategies for finding biomarkers. For two-class discrimination problems, Higher Criticism is available, an approach to define optimal cutoffs for methods like t testing for high-dimensional data. In this work, HC has been extended to multivariate methods, allowing, e.g., selection of biomarkers based on ...
Wehrens, Herman Ronald Maria Johan+1 more
openaire +2 more sources
The current state of imaging biomarker development and evaluation. [PDF]
Halligan S, Mallett S.
europepmc +1 more source
Circular RNA is enriched and stable in exosomes: a promising biomarker for cancer diagnosis
Yan Li+9 more
semanticscholar +1 more source