Biomarkers in solid organ transplantation: establishing personalized transplantation medicine. [PDF]
, 2011 Technological advances in molecular and in silico research have enabled significant progress towards personalized transplantation medicine. It is now possible to conduct comprehensive biomarker development studies of transplant organ pathologies ...
Khatri, Purvesh +3 more
core +3 more sources
Evaluation of Treatment Effect Modification by Biomarkers Measured Pre- and Post-randomization in the Presence of Non-monotone Missingness [PDF]
arXiv, 2017 In vaccine studies, investigators are often interested in studying effect modifiers of clinical treatment efficacy by biomarker-based principal strata, which is useful for selecting biomarker study endpoints for evaluating treatments in new trials, exploring biological mechanisms of clinical treatment efficacy, and studying mediators of clinical ...
arxiv
Frontiers in Cellular and Infection MicrobiologyBackgroundNumerous bacteria are involved in the etiology of bacterial vaginosis (BV). Yet, current tests only focus on a select few. We therefore designed a new test targeting 22 BV-relevant species.MethodsUsing 946 stored vaginal samples, a new qPCR ...
Ayodeji B. Oyenihi +7 more
doaj +1 more source
Genomic biomarkers in prostate cancer. [PDF]
, 2018 Prostate cancer is the most common non-cutaneous cancer among men in the United States. In the last decade there has been a rapid expansion in the field of biomarker assays for diagnosis, prognosis, and treatment prediction in prostate cancer.
Cooperberg, Matthew R +3 more
core
Differential Proteomic Analysis of Human Saliva using Tandem Mass Tags Quantification for Gastric Cancer Detection. [PDF]
, 2016 Novel biomarkers and non-invasive diagnostic methods are urgently needed for the screening of gastric cancer to reduce its high mortality. We employed quantitative proteomics approach to develop discriminatory biomarker signatures from human saliva for ...
Cao, Cheng-Xi +9 more
core +2 more sources
The Vegetation Red Edge Spectroscopic Feature as a Surface Biomarker [PDF]
arXiv, 2002 The search for Earth-like extrasolar planets is in part motivated by the potential detection of spectroscopic biomarkers. Spectroscopic biomarkers are spectral features that are either consistent with life, indicative of habitability, or provide clues to a planet's habitability. Most attention so far has been given to atmospheric biomarkers, gases such
arxiv
Efficient Principally Stratified Treatment Effect Estimation in Crossover Studies with Absorbent Binary Endpoints [PDF]
, 2019 Suppose one wishes to estimate the effect of a binary treatment on a binary endpoint conditional on a post-randomization quantity in a counterfactual world in which all subjects received treatment.
Luedtke, Alex, Wu, Jiacheng
core +1 more source
Efficient screening of predictive biomarkers for individual treatment selection [PDF]
arXiv, 2019 The development of molecular diagnostic tools to achieve individualized medicine requires identifying predictive biomarkers associated with subgroups of individuals who might receive beneficial or harmful effects from different available treatments.
arxiv
Inferring food intake from multiple biomarkers using a latent variable model [PDF]
arXiv, 2020 Metabolomic based approaches have gained much attention in recent years due to their promising potential to deliver objective tools for assessment of food intake. In particular, multiple biomarkers have emerged for single foods. However, there is a lack of statistical tools available for combining multiple biomarkers to infer food intake.
arxiv
The identification of a TNBC liver metastasis gene signature by sequential CTC‐xenograft modeling
Molecular Oncology, 2019 Triple‐negative breast cancer (TNBC) liver metastasis is associated with poor prognosis and low patient survival. It occurs when tumor cells disseminate from primary tumors, circulate in blood/lymph [circulating tumor cells (CTCs)], and acquire distinct ...
Monika Vishnoi +6 more
doaj +1 more source