Results 131 to 140 of about 2,113,927 (314)

Newsletter: A Report to the Physicians of Texas

, 1980
Quarterly newsletter from the University of Texas System Cancer Center, M.D. Anderson Hospital and Tumor Institute discussing cancer care and research to inform physicians of recent developments in the ...
McBurney, Marcia K., M.D. Anderson Hospital and Tumor Institute   +1 more
core  

Histopathological, Immunohistochemical, Molecular and Genetic Biomarkers in Differentiated Thyroid Cancer

Differentiated thyroid cancer (DTC) is the most prevalent endocrine malignancy in the world. Accurate diagnosis and prognostication are essential for optimizing its treatment and improving patient outcomes.
Dunia Aburizeg, Bilal Azab, Hala Alzaghloul, Ali M. Alabbadi, Mousa A. Al-Abbadi, Ayman Mismar, Omar Sqour, Malik Eid Juweid, Tala Qudisat, Husam Abuawad   +9 more
core   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

A novel approach to generate enzyme-free single cell suspensions from archived tissues for miRNA sequencing

SLAS Technology
Obtaining high-quality omics data at the single-cell level from archived human tissue samples is crucial for gaining insights into cellular heterogeneity and pushing the field of personalized medicine forward.
Stefan Scheuermann, Sarah Hücker, Annika Engel, Nicole Ludwig, Philipp Lebhardt, Jens Langejürgen, Stefan Kirsch   +6 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Frequency Ranking of Imaging Biomarkers for Lung Cancer Risk Stratification Using a Hybrid Elastic Net Method

Lung cancer remains the leading cause of cancer-related mortality worldwide, emphasizing the critical need for novel and robust biomarkers to improve prognostication and guide precision oncology.
Stevens, Emmy, Nezamoddin N. Kachouie, Mohamed Jaber, Emmy Stevens, Jaber, Mohamed, Kachouie, Nezamoddin N.   +5 more
core   +1 more source

Maintenance therapy in hormone receptor-positive and human epidermal growth factor receptor 2-positive metastatic breast cancer: a real-world multicenter retrospective study

Frontiers in Oncology
IntroductionThe optimal choice of maintenance therapy after standard first-line treatment for hormone receptor (HR)-and human epidermal growth factor receptor 2 (HER2)-positive metastatic breast cancer (MBC) remains uncertain. Therefore, we evaluated the
Shengnan Bao, Jia Chen, Yongmei Yin, Yongmei Yin   +3 more
doaj   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Quality control for biomarker determination in oncology: the experience of the Italian Network for Quality Assessment of Tumor Biomarkers (INQAT)

, 2002
Biomarker analysis and evaluation in oncology is the product of a number of processes (including managerial, technical and interpretation steps) which need to be monitored and controlled to prevent and correct errors and guarantee a satisfactory level of
QUERZOLI P, PLEBANI, MARIO, DE PAOLA F, NENCI I, ORLANDO C, Plebani M, E. MARUBINI, MOTTOLESE M, VOLPE S, BEVILACQUA, GENEROSO, AMADORI D, SILVESTRINI R, ITALIAN NETWORK FOR QUALITY ASSESSMENT OF TUMOR BIOMARKERS, NENCI, Italo, MARCHETTI A, SARAGONI L, DITTADI R, MARUBINI E, BEVILACQUA G, MEDRI L, MARCHETTI, ANTONIO, VERDERIO P, A. PARADISO, DAIDONE MG, A. MARCHETTI, QUERZOLI, Patrizia, R. SILVESTRINI, PARADISO A, COSTA A, IACOBACCI A, GION M   +30 more
core   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source