Results 191 to 200 of about 2,113,927 (314)

Mitochondria and Neuromast Tagging With Fluorescent Gallium‐Triapine Analogues: In Cellulo MP FLIM and Zebrafish Live Imaging

Advanced Science, EarlyView.
Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green, Michael W. Jones, Merissa Saleem, Haobo Ge, Melita Tvardauskaite, Julia Dudzic, Fernando Cortezon‐Tamarit, Rory L. Arrowsmith, Charareh Pourzand, Gabriele Kociock‐Kohn, Nicholas H. Rees, Jonathan R. Dilworth, Stephen Faulkner, Stanley W. Botchway, David Gurevich, Sofia I. Pascu   +15 more
wiley   +1 more source

Tumor Mutational Landscape and Its Correlation With Histopathological Characteristics in Breast Cancer. [PDF]

Cancer Genomics Proteomics
Papadopoulou E, Stathoulopoulou M, Matiatou M, Karathanasis P, Xenakis X, Pesmatzoglou G, Fyssas I, Louis K, Maniatis D, Ekmektzoglou A, Alexandrou D, Kalivopoulos C, Kanistras C, Katsiakis N, Konstantiadou I, Kavazis C, Kokolakis A, Papaioannou N, Sachoulidou A, Sfakianakis E, Triantafyllidou S, Filippidou S, Damaskos C, Lazaridis G, Koinis F, Biziota E, Koutras A, Kotsori A, Venizelos V.   +28 more
europepmc   +1 more source

Combating Inflammation and Promoting Anabolism in Osteoarthritic Cartilage Defect With an MMP13‐Sensing Dual‐Drug Scaffold

Advanced Science, EarlyView.
ABSTRACT Osteoarthritis (OA) is a widespread degenerative joint condition marked by progressive cartilage breakdown, and a chronic inflammatory microenvironment, where conventional therapies largely fail to halt disease progression. To address this unmet need, an intra‐articularly implantable, disease‐responsive scaffold was developed for combinatorial
Zhen Zhang, Bangheng Liu, Yulei Mu, Huiqun Zhou, Liang Ma, Chenjie Xu, Dong‐An Wang   +6 more
wiley   +1 more source

Multi-Omics-Enabled Precision Strategies for Overcoming CAR-T Therapy Limitations in Gastrointestinal Malignancies. [PDF]

Biofactors
Su K, Tan Z, Li H, You K, Xiao S, Chen H, Li D, Liu X, Du X, Hu J, He K, Xu Y, Chen J, Han Y.   +13 more
europepmc   +1 more source

Chemoproteomic Identification of AKT2 as a Paclitaxel‐Binding Protein via C─C Bond‐Linked Probe PTX‐4 in Paclitaxel‐Resistant Breast Cancer

Advanced Science, EarlyView.
ABSTRACT Breast cancer remains one of the most prevalent malignancies among women, and taxane‐based chemotherapies such as paclitaxel and docetaxel are central to standard treatment regimens. However, drug resistance in breast cancer limits therapeutic efficacy and contributes to recurrence and metastasis.
Kai Wang, Yuqing Yuan, Wei Shen, Xiuxiu Yang, Xiaokang Wu, Haihua Zhou, Yi Hu, Qing Zhu   +7 more
wiley   +1 more source

Recent advancement in inflammatory biomarkers for cervical cancer diagnosis and therapy. [PDF]

Front Oncol
Sahu U, Singh S, Jain S, Samant M, Khare P.   +4 more
europepmc   +1 more source

Evaluation of circulating tumor DNA as a biomarker for gynecological tumors

Chinese Medical Journal, 2020
Kang-Sheng Liu, Hua Tong, Tai-Ping Li, Ya-Jun Chen, Yan-Jie Yin, Xiu-Yuan Hao   +5 more
openaire   +3 more sources

Single‐Cell Dissection of Therapy‐Induced Remodeling Uncovers a Fibroblast‐Driven Immunosuppressive Niche and Targetable Vulnerabilities in Lethal Prostate Cancer

Advanced Science, EarlyView.
Single‐cell longitudinal profiling reveals that androgen‐deprivation therapy induces a DPT+ fibroblast‐complement axis that suppresses macrophage inflammation and drives CD8+ T cell exhaustion in prostate cancer. Concurrently, resistant epithelial subpopulations persist and engage TSPAN1‐ and NRXN1‐mediated programs promoting CRPC and neuroendocrine ...
Yang Chen, Dandan Dong, Jinling Liao, Naikai Liao, Mengqi Liu, Qin Zhang, Siting Chen, Qi Liu, Ying Lu, Tianyu Li, Chunlin Zou, Qiong Song, Qiuyan Wang, Jian Liang, Qiji Xie, Chengyang Li, Mengyun Wang, Jiwen Cheng, Zengnan Mo, Gong‐Hong Wei   +19 more
wiley   +1 more source

Special Issue "Epigenetic Genes, Biomarkers and Immunotherapy in Cancers". [PDF]

Int J Mol Sci
Oleksiewicz U.
europepmc   +1 more source

Metabolite biomarkers for tumors [PDF]

Analytical Chemistry, 2005
openaire   +1 more source