Results 31 to 40 of about 231,796 (189)

Expression of TIM3/VISTA checkpoints and the CD68 macrophage-associated marker correlates with anti-PD1/PDL1 resistance: implications of immunogram heterogeneity. [PDF]

, 2020
Although immunotherapies have achieved remarkable salutary effects among subgroups of advanced cancers, most patients do not respond. We comprehensively evaluated biomarkers associated with the "cancer-immunity cycle" in the pan-cancer setting in order ...
Dressman, Devin, Eskander, Ramez, Glenn, Sean T, Goodman, Aaron, Ikeda, Sadakatsu, Kato, Shumei, Kumaki, Yuichi, Kurzrock, Razelle, Lee, Suzanna, Lenzo, Felicia L, Morrison, Carl, Nikanjam, Mina, Okamura, Ryosuke, Papanicolau-Sengos, Antonios   +13 more
core   +1 more source

Biomarkers of tumor invasiveness in proteomics (Review)

International Journal of Oncology, 2020
Over the past two decades, quantitative proteomics has emerged as an important tool for deciphering the complex molecular events involved in cancers. The number of references involving studies on the cancer metastatic process has doubled since 2010, while the last 5 years have seen the development of novel technologies combining deep proteome coverage ...
Pouliquen, Daniel, L., Boissard, Alice, Coqueret, Olivier, Guette, Catherine   +3 more
openaire   +7 more sources

MiRNAs as Potential Prognostic Biomarkers for Metastasis in Thin and Thick Primary Cutaneous Melanomas. [PDF]

, 2019
Background/Aim: The identification of novel prognostic biomarkers for melanoma metastasis is essential to improve patient outcomes. To this aim, we characterized miRNA expression profiles in relation to metastasis in melanoma and correlated miRNAs ...
Bucalo, Agostino, Calvieri, Stefano, Donati, Pietro, Frascione, Pasquale, Gaggiano, Emanuela, Grassi, Sara, Ottini, Laura, Richetta, Antonio Giovanni, Rizzolo, Piera, Silvestri, Valentina, Soda, Giuseppe, Valentini, Virginia, Zelli, Veronica   +12 more
core   +1 more source

Exosome as potential biomarkers for gastrointestinal tumors

Medicine, 2021
Abstract Introduction: Exosomes are polyvesicles that are formed by invagination of intracellular lysosomal particles, and are released into the extracellular matrix after the fusion of polyvesicular outer membrane and cell membrane.
Jinlong Zhang, Shudan Fu, Wenshuo Chen, Haijin Chen   +3 more
openaire   +3 more sources

Investigating the benefits of molecular profiling of advanced non-small cell lung cancer tumors to guide treatments. [PDF]

, 2018
In this study we utilized data on patient responses to guided treatments, and we evaluated their benefit for a non-small cell lung cancer cohort. The recommended therapies used were predicted using tumor molecular profiles that involved a range of ...
Alifrangis, C, Belluz, LDB, Carter, P, Cereser, B, Chandrasinghe, P, Krell, J, Lim, E, Moderau, N, Poyia, F, Stebbing, J, Tabassum, N, Zhang, H   +11 more
core   +2 more sources

Biomarkers for Wilms Tumor: A Systematic Review [PDF]

Journal of Urology, 2016
Wilms tumor is the most common childhood renal malignancy and the fourth most common childhood cancer. Many biomarkers have been studied but there has been no comprehensive summary. We systematically reviewed the literature on biomarkers in Wilms tumor to quantify the prognostic implications of the presence of individual tumor markers.We searched for ...
Cone, Eugene B, Dalton, Stewart S, Van Noord, Megan, Tracy, Elizabeth T, Rice, Henry E, Routh, Jonathan C   +5 more
openaire   +5 more sources

Epigenetics in diagnosis, prognostic assessment and treatment of cancer:An update [PDF]

, 2014
Cancer cells contain multiple genetic and epigenetic changes. The relative specificity of many epigenetic changes for neoplastic cells has allowed the identification of diagnostic, prognostic and predictive biomarkers for a number of solid tumors and ...
Briasoulis, Evangelos, Crook, Tim, Hatzimichael, Eleftheria, Lagos, Konstantinos, Sim, Van Ren   +4 more
core   +4 more sources

Salivary Biomarkers for Oral Squamous Cell Carcinoma Diagnosis and Follow-Up: Current Status and Perspectives [PDF]

, 2019
Oral cancer is the sixth most common cancer type in the world, and 90% of it is represented by oral squamous cell carcinoma (OSCC). Despite progress in preventive and therapeutic strategies, delay in OSCC diagnosis remains one of the major causes of high
Campisi, Giuseppina, Cristaldi, Marta, Di Fede, Olga, Giuliana, Giovanna, Mauceri, Rodolfo, Panzarella, Vera   +5 more
core   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Biomarkers of Pineal Region Tumors: A Review [PDF]

Ochsner Journal, 2019
Background: The pineal gland, a small, pinecone-shaped organ deep within the brain, is responsible for producing melatonin. The gland consists of pineal parenchymal cells and glial cells that can form neoplasms. Pineal region neoplasms can also arise from germ cells and adjacent structures.
Carr, Christopher, O'Neill, Brannan E., Hochhalter, Christian B., Strong, Michael J., Ware, Marcus L.   +4 more
openaire   +3 more sources